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  1. 461
    “…Furthering our understanding of this novel ligand-receptor interaction will shed new light on the search of ligands for their cognate receptors, especially those orphan receptors without known ligands, and deepen our knowledge of the fundamental research in membrane receptor biology and the translational application toward the development of precision medicine.…”
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    A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases
  2. 462
    “…There exists solid evidence that endogenous galanin and galanin agonists exert anticonvulsive actions mediated both by galanin 1 receptor (GAL1‐R) and galanin 2 receptor (GAL2‐R). …”
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    Effects of galanin receptor 2 and receptor 3 knockout in mouse models of acute seizures
  3. 463
    “…A major predictor of the efficacy of natural or synthetic cannabinoids is their binding affinity to the cannabinoid type I receptor (CB(1)) in the central nervous system, as the main psychological effects of cannabinoids are achieved via binding to this receptor. …”
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    Receptor Binding Affinities of Synthetic Cannabinoids Determined by Non-Isotopic Receptor Binding Assay
  4. 464
    “…We evaluated redundant and receptor-specific activities of TRADD, RIPK1, and FADD in RIPK3-expressing HeLa cells lacking expression of these proteins or any combination of two of these factors. …”
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    Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling
  5. 465
    “…Receptor kinases (RK) constitute the largest protein kinase family in plants. …”
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    Classification and Interactions of LRR Receptors and Co-receptors Within the Arabidopsis Plasma Membrane – An Overview
  6. 466
    “…Hyperekplexia disease is usually caused by naturally occurring point mutations in glycine receptors (GlyRs). However, the γ-aminobutyric acid type A receptor (GABA(A)R) seems to be also involved regarding the therapeutic basis for hyperekplexia using benzodiazepines, which target GABA(A)Rs but not GlyRs. …”
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    Human Hyperekplexic Mutations in Glycine Receptors Disinhibit the Brainstem by Hijacking GABA(A) Receptors
  7. 467
    “…The histamine H2 receptor (H2R) is a G protein‐coupled receptor that mediates cyclic AMP production, protein kinase A activation, and MAP kinase signaling. …”
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    Phagocytosis by macrophages depends on histamine H2 receptor signaling and scavenger receptor 1
  8. 468
    por Sugiyama, Tetsuya
    Publicado 2018
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    Special Issue for Purinergic Receptors, Particularly P2X(7) Receptor, in the Eye
  9. 469
    “…The glucocorticoid and progesterone receptors (GR and PR) are closely related members of the steroid receptor family. …”
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    The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells
  10. 470
    “…Adenosine and its receptors exert a potent control on the cardiovascular system. …”
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    Adenosine Receptor Profiling Reveals an Association between the Presence of Spare Receptors and Cardiovascular Disorders
  11. 471
    “…Epidermal growth factor receptor expression level was correlated to DDSI diagnostic potential, which was found to be robust to spatial pattern expression variation. …”
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    Diagnostic performance of receptor-specific surgical specimen staining correlates with receptor expression level
  12. 472
    “…GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharmacology, however, remains scarcely understood. …”
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    The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
  13. 473
    “…We identify scavenger receptor B1 (SR-B1) as an EsxA receptor on airway M cells. …”
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    Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis
  14. 474
    por Chung, Man-Kyo, Ro, Jin Y
    Publicado 2020
    “…Several members of the transient receptor potential (TRP) family, such as transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1, also play essential roles in the development of spontaneous pain and mechanical hypersensitivity in craniofacial muscles. …”
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    Peripheral glutamate receptor and transient receptor potential channel mechanisms of craniofacial muscle pain
  15. 475
    Materias: “…Steroid Hormones and Receptors…”
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    OR12-02 When the Glucocorticoid Receptor Meets the Mineralocorticoid Receptor in the Nucleus of Human Cells
  16. 476
    “…Evidence accumulates that the functional plasticity of insulin and insulin-like growth factor signaling in insects could spring, among others, from the multiplicity of insulin receptors (InRs). Their multiple variants may be implemented in the control of insect polyphenism, such as wing or caste polyphenism. …”
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    Complex Evolution of Insect Insulin Receptors and Homologous Decoy Receptors, and Functional Significance of Their Multiplicity
  17. 477
    “…Chimeric antigen receptor (CAR)-T cells have demonstrated significant clinical potential; however, their strong antitumor activity may cause severe adverse effects. …”
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    Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold
  18. 478
    “…Here, we identify compounds capable of rescuing the activity of mutant gonadotropin-releasing hormone receptor or GnRHR which, is sequestered within the cell and if dysfunctional leads to Hypogonadotropic Hypogonadism. …”
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    Rescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity
  19. 479
    “…These plasma membrane receptors belong to large gene/protein families that are not easily classified computationally. …”
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    Computational identification of receptor-like kinases “RLK” and receptor-like proteins “RLP” in legumes
  20. 480
    “…In Alzheimer's disease (AD), decreases in the amount and synaptic localization of AMPA receptors (AMPARs) result in weakened synaptic activity and dysfunction in synaptic plasticity, leading to impairments in cognitive functions. …”
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    Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease
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