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61“…Recent studies have shown that during the evolution of African trypanosome species the receptor has diversified in function from a hemoglobin receptor predominantly expressed in the tsetse fly to a haptoglobin–hemoglobin receptor predominantly expressed in the mammalian bloodstream. …”
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62“…A recently reported rapid potentiation of NMDA receptors by Group I metabotropic glutamate receptors (mGluRIs) via a Homer protein link is distinct from the classical, relatively slow inhibitory G-protein-associated signaling triggered by mGluRI activation. …”
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63“…Included in our review are well-established AMPA receptor interactants such as GRIP1 and PICK1, the classical auxiliary subunits TARP and CNIH, and the newest additions to AMPA receptor native complexes.…”
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64por Kamijo, Keiichi“…We herein report a rare case of a 41-year-old woman with painless thyroiditis who was positive for thyrotropin (TSH) receptor-blocking (TBAbs) and receptor-stimulating autoantibodies (TSAbs) in the thyrotoxic phase. …”
Publicado 2019
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65“…Receptology has been complicated with enhancements in our knowledge of G‐protein‐coupled‐receptor (GPCR) biochemistry. This complexity is exemplified by the pharmacology of melatonin receptors. …”
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66por Furmaniak, J., Sanders, J., Sanders, P., Miller-Gallacher, J., Ryder, M. M., Rees Smith, B.“…Studies on the TSH receptor (TSHR) have numerous practical applications in vitro and in vivo. …”
Publicado 2020
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67“…The prolactin receptor (PRLR) signals predominantly through the JAK2-STAT5 pathway regulating multiple physiological functions relating to fertility, lactation, and metabolism. …”
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68por Batishchev, Oleg V., Kuzmina, Natalia V., Mozhaev, Andrey A., Goryashchenko, Alexander S., Mileshina, Ekaterina D., Orsa, Alexander N., Bocharov, Eduard V., Deyev, Igor E., Petrenko, Alexander G.“…The insulin receptor (IR), insulin-like growth factor 1 receptor (IGF-1R), and insulin receptor-related receptor (IRR) form a mini family of predimerized receptor-like tyrosine kinases. …”
Publicado 2021
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70“…Many receptors are able to undergo heteromerisation, leading to the formation of receptor complexes that may have pharmacological profiles distinct from those of the individual receptors. …”
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71“…GLP-1R (glucagon-like peptide-1 receptor) mediates the ‘incretin effect’ and many other anti-diabetic actions of its cognate ligand, GLP-1 (glucagon-like peptide-1). …”
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72“…Second, to clarify whether there is any disparity in hormone receptor status between primary and metastatic or recurrent tumors, we immunohistochemically studied 117 specimens including the above 35 specimens obtained from metastatic or recurrent breast cancer patients using monoclonal anti‐ER and progesterone receptor (PgR) antibodies. …”
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75por Jung, Mi‐Hyang, Lee, Ju‐Hee, Lee, Chan Joo, Shin, Jeong‐Hun, Kang, Si Hyuck, Kwon, Chang Hee, Kim, Dae‐Hee, Kim, Woo‐hyeun, Kim, Hack Lyoung, Kim, Hyue Mee, Cho, In Jeong, Cho, Iksung, Hwang, Jinseub, Ryu, Soorack, Kang, Chaeyeong, Lee, Hae‐Young, Chung, Wook‐Jin, Ihm, Sang‐Hyun, Kim, Kwang Il, Cho, Eun Joo, Sohn, Il‐Suk, Park, Sungha, Shin, Jinho, Ryu, Sung Kee, Rhee, Moo‐Yong, Kang, Seok‐Min, Pyun, Wook Bum, Cho, Myeong‐Chan, Sung, Ki‐ChulMaterias: “…Angiotensin‐receptor Blockers and Cancer…”
Publicado 2021
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76por Schüler-Toprak, Susanne, Skrzypczak, Maciej, Gründker, Carsten, Ortmann, Olaf, Treeck, Oliver“…Both the ovary and endometrium are affected by estrogens and their receptors. The well-known estrogen receptor α (ERα) mediates estrogen effects such as the activation of cell proliferation. …”
Publicado 2023
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77“…As one approach to understand the molecular interactions that support HIV virion binding to human mucosal surfaces, we have examined the distribution of the primary HIV receptor CD4, the alternate HIV receptors heparan sulfate proteoglycan (HS) and galactosyl ceramide (GalCer) and the co-receptors CXCR4 and CCR5 in palatine tonsil. …”
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78por Durum, Scott K., Candèias, Serge, Nakajima, Hiroshi, Leonard, Warren J., Baird, Allison M., Berg, Leslie J., Muegge, Kathrin“…VDJ recombination of T cell receptor and immunoglobulin loci occurs in immature lymphoid cells. …”
Publicado 1998
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79por Lowery, Aoife J, Miller, Nicola, Devaney, Amanda, McNeill, Roisin E, Davoren, Pamela A, Lemetre, Christophe, Benes, Vladimir, Schmidt, Sabine, Blake, Jonathon, Ball, Graham, Kerin, Michael J“…The aims of this study were to identify miRNA signatures that accurately predict the oestrogen receptor (ER), progesterone receptor (PR) and HER2/neu receptor status of breast cancer patients to provide insight into the regulation of breast cancer phenotypes and progression. …”
Publicado 2009
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80“…The first and third extracellular loops (ECL) of G protein-coupled receptors (GPCRs) have been implicated in ligand binding and receptor function. …”
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