“…To understand this postulate, one must jettison isolationist or reductionist ideas of chemoreceptor and baroreceptor functions of the carotid body or sinus, respectively, and consider their interaction and interdependence both locally and centrally where some of its efferents merge. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We focus our message upon the reductionist use of two forms of phase separation as biochemical assays to study how LC domains might function in living cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To date, most observations have been made in reductionist cell culture systems, or as snapshots from patient cohorts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The low number of antimicrobial active extracts and compounds suggests that antibacterial and antimycobacterial drug discovery needs to have a fresh look at ethnobotanical information, diverting from too reductionist an approach and better taking into account that the descriptions of symptoms and concepts of underlying diseases are different in traditional African and modern Western medicine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This technical progression has enabled increasingly deep insights into the regulation of perception and behavior with remarkable precision. The capacity of reductionist approaches to identify the function of isolated circuits is undeniable but many behaviors require rapid integration of diverse inputs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To decipher this, we used a reductionist approach with well-defined micropatterns functionalized with immunoglobulins mimicking immune complexes at planar interfaces and bacteriamimetic microbeads. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Stress response helps microorganisms survive extreme environmental conditions and host immunity, making them more virulent or drug resistant. Although both reductionist approaches investigating specific genes and systems approaches analyzing individual stress conditions are being used, less is known about gene networks involved in multiple stress responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Within the complex milieu of a cell, which comprises a large number of different biomolecules, interactions are critical for function. In this post-reductionist era of biochemical research, the ‘holy grail’ for studying biomolecular interactions is to be able to characterize them in native environments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Within this scenario of increasing data availability, Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. …”
Enlace del recurso
Enlace del recurso

“…Simplified, reductionist approaches to curriculum design and delivery are pervasive in science education. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nutrition research and policy activities were framed mostly within a reductionist paradigm in which foods were analysed as being a collection of their constituent nutrients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The literature suggests that while the traditional reductionist approach remains relevant and yields quicker results, the food matrix approach, which involves engineering food microstructure, is a more complex process that may take longer to implement in developing economies. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nutrition research and policy activities were framed mostly within a reductionist paradigm in which foods were analysed as being a collection of their constituent nutrients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It emphasizes a public health approach for efficient use of resources in a new flexible framework for risk management, reductionist approaches to risk assessment and characterization, increased public involvement, and various methods for managing such public involvement. …”
Enlace del recurso
Enlace del recurso

“…These results suggest a novel role for Mdm2 as well as for p53 sumoylation in the recruitment of p53 to nuclear bodies. The reductionist yeast model that was established and validated in this study will now allow to incrementally study simplified parts of the intricate p53 network, thus helping elucidate the core mechanisms of p53 regulation as well as test novel strategies to counteract p53 malfunctions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It requires moving from a reductionist framework of seeking to destroy aberrant cells and pathways to a transdisciplinary systems biology approach aimed at reversing multiple levels of dysfunction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…By means of the analysis capabilities provided by the web interface, it is possible to overcome the limits of reductionist resources, enabling predictions that can lead to new experiments.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Conceptual bases of many of the PROMs was either restricted or based on reductionist biomedical models. All of the PROMs were found to consist of fixed scales. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Interphase chromatin compaction well above the 30-nm fiber is well documented, but the structural motifs underlying this level of chromatin folding remain unknown. Taking a reductionist approach, we analyzed in mouse embryonic stem (ES) cells and ES-derived fibroblasts and erythroblasts the folding of 10–160-megabase pair engineered chromosome regions consisting of tandem repeats of bacterial artificial chromosomes (BACs) containing ∼200 kilobases of mammalian genomic DNA tagged with lac operator (LacO) arrays. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The focus of this reductionist approach is on the ‘average patient’ in the group being observed rather than the individual patient working with the individual care provider. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso