“…Thus, we argue here that transfers by non-canonical minute quantities of miRNAs must consider the EV carrier effects of functional low levels of exosome transferred miRNA that may not fit conventional reductionist stoichiometric concepts. Accordingly, we have examined traditional stoichiometry vs. systems biology that may be more appropriate for delivered exosome functional responses. …”
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“…Yet, the prevalent research paradigm is reductionist. Focusing on infectious diseases, reductionist and non-reductionist views are here described. …”
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“…Second, we perform a preliminary study that illustrates a top-down approach to potential MQS. In summary, reductionist arguments against MQS are not justifiable. …”
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“…The science of nutrition has long been entrapped in reductionist interpretation of details, a source of great confusion. …”
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“…Here we examine examples of the farming of coevolutionary systems, focusing on the mutually amplifying roles of large-scale psychosocial stress, economic structure, and reductionist interventions in the ecology and evolution of highly adaptive disease organisms. …”
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“…This review will highlight the development of the major assays and methods that have allowed this combined reductionist and comparative approach to be so fruitful. …”
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“…The proportion of individuals who benefit was taken as everyone who would, without treatment, have an MI or stroke (holistic model), rather than limiting the benefit to the proportion calculated from the relative risk reduction (reductionist model), as is current practice. Under the holistic model, 33 % of people who take the polypill from age 50 benefit, gaining, on average, 8 years of life without an MI or stroke (19 % and 14 years under the reductionist model). …”
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“…The aim of this paper is to argue that a strictly reductionist approach to psychiatry represents a theoretical and clinical obstacle to a fruitful synthesis between neurobiological and sociocultural aspects of the sciences of mind. …”
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“…Biology is reaching a convergence point of its historic reductionist and modern holistic approaches to understanding the living system. …”
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“…Two methods were applied: (i) a “reductionist” one, which analyzes each cell type separately, and (ii) a “non-reductionist” method, which estimates multi-cellularity. …”
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“…CONCLUSIONS: Most of Australia’s policy actions to reduce added sugar consumption are reductionist. Preferencing nutrient specific, first-order policy actions could reflect the influence of vested interests, a historically dominant reductionist orientation to nutrition science and policy, and the perceived difficulty of pursuing second- or third-order changes. …”
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“…I also consider theoretical background of the concept of the gene in the ideas of empiricism and experimentalism, as well as reductionist and anti-reductionist narratives on the concept. …”
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“…A reductionist view of mental health tends to give limited results. …”
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“…More relevant indicators may be developed in the future, taking us further toward reconciliation between reductionist and holistic approaches to change assessment and understanding. …”
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“…The author explains to Matin Durrani why he objects to the reductionist world view of particle physicists. (2 pages0…”
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“…I will here pick up on a suggestion made by Greve (2023) in this journal, namely that a proper understanding of lifespan development means defending a non-reductionist psychology taking biological processes seriously, but without reducing psychology to physiology. …”
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“…Systems radiation biology is increasingly gaining ground, but the gap between reductionist and holistic approaches is becoming larger. …”
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“…Systems and molecular reductionist views on organisms were completely opposed to each other. …”
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“…We focus principally on reductionist studies performed using powerful model secretory systems and cell-free reconstitution assays. …”
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“…The successes emanating from the prevailing Western mental model of health and disease focusing on the individual and the reductionist approach to scientific inquiry is unquestioned. …”
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