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  1. 61
    por Hankey, Alex
    Publicado 2012
    “…One consequence is that the world is not necessarily reductionist i.e. based solely on the properties of its tiniest constituents. …”
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    The ontological status of western science and medicine
  2. 62
    “…What has been endangered by the search for (the) ultimate truth? Has the dream of reductionist reason created any monsters? Is big science one such monster? …”
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    Reductionism, emergence and levels of reality: the importance of being borderline
  3. 63
    por Maeda, Hiroshi, Khatami, Mahin
    Publicado 2018
    “…For over six decades reductionist approaches to cancer chemotherapies including recent immunotherapy for solid tumors produced outcome failure-rates of 90% (±5) according to governmental agencies and industry. …”
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    Analyses of repeated failures in cancer therapy for solid tumors: poor tumor-selective drug delivery, low therapeutic efficacy and unsustainable costs
  4. 64
    “…Among evolutionists, selfish gene theory promotes reductionist approaches while multilevel selection theory encourages a context-sensitive approach that appreciates that individuals and groups can both matter. …”
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    Core design principles for nurturing organization-level selection
  5. 65
    “…Some of the most frequently activated oncogenes driving diverse cancers are c-MYC, EGFR, HER2, AKT, KRAS, BRAF, and MEK. Using a reductionist approach, we explored how cellular proteomes are remodeled in isogenic cell lines engineered with or without these driver oncogenes. …”
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    Discovery Proteomics Analysis Determines That Driver Oncogenes Suppress Antiviral Defense Pathways Through Reduction in Interferon-β Autocrine Stimulation
  6. 66
    “…Previous research on MNDs has focused on understanding the pathobiology of a single, specific gene mutation and targeting therapies to that pathobiology. This reductionist approach has yielded therapeutic options for a specific disorder, in this case SMA. …”
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    Biological networks and complexity in early-onset motor neuron diseases
  7. 67
    Publicado 1999
    Tabla de Contenidos: “…/ Nancy Cartwright -- The objections of an unashamed reductionist / Stephen Hawking -- Response / Roger Penrose.…”
    Libro
    The large, the small, and the human mind /
  8. 68
    “…Intentional knowledge, discharging in reductionist therapies, disregards the risk-absorbing background knowledge of the tumor’s living world including the holistic communication processes, which we rely on in every therapy. …”
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    Principles of Modular Tumor Therapy
  9. 69
    “…Using examples obtained from reductionist and community-level approaches, we discuss the fundamental role of microbe-microbe interactions (prokaryotes and micro-eukaryotes) for microbial community structure and plant health. …”
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    Microbial interactions within the plant holobiont
  10. 70
    “…Built on evidence from an array of reductionist and non-reductionist literature, we suggest that food systems researchers and policymakers adapt current methods and theoretical frameworks to appropriately contextualise aquatic animals in broader food systems. …”
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    More Than Fish—Framing Aquatic Animals within Sustainable Food Systems
  11. 71
    “…In order to relate these reductionist experiments to the gene expression responses to feeding on noni fruit itself, we fed rotten noni fruit to adult female D. sechellia and performed RNA-sequencing. …”
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    Genomics analysis of Drosophila sechellia response to Morinda citrifolia fruit diet
  12. 72
    por Tiefer, Leonore
    Publicado 2006
    “…Tiefer highlights key steps in the "creation" of a new diagnosis, female sexual dysfunction, and of the campaign to challenge its reductionist approach to women's sexual problems.…”
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    Female Sexual Dysfunction: A Case Study of Disease Mongering and Activist Resistance
  13. 73
    por Elser, James J, Hamilton, Andrew
    Publicado 2007
    “…There is a call for biological science to move away from the reductionist focus of the past, but there are large-scale integrative efforts already underway; biological stoichiometry provides one such example.…”
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    Stoichiometry and the New Biology: The Future Is Now
  14. 74
    “…Notably, parents do not uncritically adopt or accept (sometimes reductionist) neurobiological and/or psychological knowledge; rather, they reflect on whether and when it is applicable to and relevant for raising their children. …”
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    Neurobiological limits and the somatic significance of love: Caregivers’ engagements with neuroscience in Scottish parenting programmes
  15. 75
    “…We used the previously established reductionist, synthetic approach to identify factors that contribute to the surface binding of S. enterica serovar Typhimurium to leaves of L. sativa by expressing all known adhesive structures by remote control expression system.…”
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    Factors Required for Adhesion of Salmonella enterica Serovar Typhimurium to Lactuca sativa (Lettuce)
  16. 76
    por Kaneko, Kunihiko
    Publicado 2006
    “…This book examines life not from the reductionist point of view, but rather asks the question: what are the universal properties of living systems and how can one construct from there a phenomenological theory of life that leads naturally to complex processes such as reproductive cellular systems, evolution and differentiation? …”
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    Life: An Introduction to Complex Systems Biology
  17. 77
    “…In the first of a two part series, Ahn and colleagues discuss the reductionist approach pervading medicine and explain how a systems approach (as advocated by systems biology) may complement reductionism.…”
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    The Limits of Reductionism in Medicine: Could Systems Biology Offer an Alternative?
  18. 78
    por Noble, Denis
    Publicado 2012
    “…Holistic treatments depend on the same insight and can therefore be successful in practice where reductionist approaches would fail.…”
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    Why integration?
  19. 79
    “…Furthermore, structural constraints imposed by the QOF encouraged reductionist approaches to case-finding for depression in consultations for CHD and diabetes. …”
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    Talking about depression: a qualitative study of barriers to managing depression in people with long term conditions in primary care
  20. 80
    “…We exposed neuronal cultures to pre-determined and clinically relevant pathophysiological levels of tumor necrosis factor-α (TNF), interleukin-6 (IL-6) and interleukin-1β (IL-1β), shown to be present in the inflammatory aftermath of TBI. Data from this reductionist human model were then compared with our in vivo data. …”
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    Elucidating Pro-Inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model
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