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81“…Research within visual cognition has made tremendous strides in uncovering the basic operating characteristics of the visual system by reducing the complexity of natural vision to artificial but well-controlled experimental tasks and stimuli. This reductionist approach has for example been used to assess the basic limitations of visual attention, visual working memory (VWM) capacity, and the fidelity of visual long-term memory (VLTM). …”
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82por Morash, Michael G., Nixon, Jessica, Shimoda, Lori M. N., Turner, Helen, Stokes, Alexander J., Small-Howard, Andrea L., Ellis, Lee D.“…In this paper, we utilize a reductionist approach to identify minimal essential mixtures (MEMs) of these components that are amenable to pharmacological formulation. …”
Publicado 2022
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83por Pismen, Len“…This book is a personal account of some aspects of the emergence of modern science, mostly from the viewpoint of those branches of physics which provided the much needed paradigm shift of "more is different" that heralded the advent of complexity science as an antidote to the purely reductionist approach in fundamental physics. It is also about the humans that have helped to shape these developments, including personal reminiscences and the realization that the so-called exact sciences are inevitably also a social endeavour with all its facets. …”
Publicado 2018
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84“…Also Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. …”
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85“…Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of co-evolving tumor cells and host immunity. …”
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86“…It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. …”
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87por Luis, Elkin O., Akrivou, Kleio, Bermejo-Martins, Elena, Scalzo, Germán, Orón, José Víctor“…Without intending to be reductionist, we believe that these aspects are essential for optimally engaging in IRs and for the personal constitution. …”
Publicado 2022
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88por Beutler, Bruce“…A pure reductionist approach can sometimes be used to solve an exceptionally complicated biologic problem, and sepsis is nothing if not complicated. …”
Publicado 2003
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89por Salcedo Fidalgo, Hernando“…It is with this alternative and a non-reductionist gaze that we intend to present an analysis of the current health crash and the possibilities of structural action on the determinants that have led humanity to the threshold of collapse of the most precious values of modernity.…”
Publicado 2020
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90“…Strengths of the approach include ease, speed, and breadth of analysis, whereas drawbacks include loss of physiological regulation in reductionist systems and indirect assessment of CPT-1 enzymatic activity. …”
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91“…The reductionist concept, based on the ligand–receptor interaction, is not a suitable model for adaptogens, and herbal preparations affect multiple physiological functions, revealing polyvalent pharmacological activities, and are traditionally used in many conditions. …”
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92“…Although tcm is normally implemented as a whole system, recent reductionist research suggests mechanisms for the effects of acupuncture, herbs, and nutrition within the scientific model of biomedicine. …”
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93“…Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency. …”
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94por Sintchenko, Vitali“…The developments in informatics have been critical in boosting the translational science and in supporting both reductionist and integrative research paradigms.…”
Publicado 2009
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95“…The purpose of this perspective is to provide a logical basis for a new approach to classifying human disease that uses conventional reductionism and incorporates the non-reductionist approach of systems biomedicine.…”
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96“…To gain insight in PML-NB function, reductionist and high throughput techniques have been employed to identify PML-NB proteins. …”
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97“…This long accepted IgE/FcεRI/mast cell paradigm, on which the definition of immediate hypersensitivity was based in the Gell and Coomb’s classification, appears too reductionist. Recently accumulated evidence indeed requires that not only IgE but also IgG antibodies, that not only FcεRI but also FcγR of the different types, that not only mast cells and basophils but also neutrophils, monocytes, macrophages, eosinophils, and other myeloid cells be considered as important players in allergy. …”
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98por Schramme, Thomas“…This article discusses the reasonableness of the concept of mental disorder in relation to reductionist and eliminativist strategies in the philosophy of mind. …”
Publicado 2013
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99por Benning, Tony B“…A commitment to an integrative, non-reductionist clinical and theoretical perspective in medicine that honors the importance of all relevant domains of knowledge, not just “the biological,” is clearly evident in Engel’s original writings on the biopsychosocial model. …”
Publicado 2015
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100“…In this Perspective, we articulate the need for model microbiome systems that enable experimentation in both community and reductionist frameworks, with an emphasis on understanding the role of specialized metabolites in microbial communities. …”
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