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2501por Rahal, Zahraa, El Nemr, Shaza, Sinjab, Ansam, Chami, Hassan, Tfayli, Arafat, Kadara, Humam“…This limitation is further amplified when considering the variable etiologic factors in NSCLC pathogenesis among different regions around the globe. In this review, we present our current knowledge of genomic alterations arising during early stages of smoking-induced lung cancer initiation and progression, including discussing the premalignant airway field of injury induced by smoking. …”
Publicado 2017
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2502
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2503por Psarelis, S., Richards, B.D. Wensley, Kourounis, G., Tabet, P.P., Weinberg, S.E., Johnson, P.Enlace del recurso
Publicado 2015
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2504por Lover, Andrew A., Harvard, Kelly E., Lindawson, Alistair E., Smith Gueye, Cara, Shretta, Rima, Gosling, Roly, Feachem, Richard“…Andrew Lover and colleagues discuss regional malaria initiatives, the strengths and challenges.…”
Publicado 2017
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2505por Cambiaghi, Barbara, Vasques, Francesco, Mörer, Onnen, Ritter, Christian, Mauri, Tommaso, Kunze-Szikszay, Nils, Holke, Karin, Collino, Francesca, Maiolo, Giorgia, Rapetti, Francesca, Schulze-Kalthoff, Elias, Tonetti, Tommaso, Hahn, Günter, Quintel, Michael, Gattinoni, Luciano“…We studied the effects of regional perfusion block in normal lungs and in the lungs that had been conditioned by lavage with 500 ml saline and high V (T) (20 ml kg(−1)) ventilation. …”
Publicado 2017
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2507
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2508por de Faria Santos, Amanda, Fernandes Carrijo, Tiago, Marques Cancello, Eliana, Coletto Morales-Corrêa e Castro, Adriana“…However, biogeographic and phylogeographic information of termites of this region is limited compared to other world geographic regions. …”
Publicado 2017
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2509“…Their genome contains at least one ambisense RNA segment that carries two oppositely oriented reading frames separated by an intergenic region. It is believed that a structural RNA element within the intergenic region is involved in transcription termination. …”
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2511por Nartey, Yvonne, Hill, Philip C., Amo-Antwi, Kwabena, Nyarko, Kofi M., Yarney, Joel, Cox, Brian“…The incidence and mortality rates of cervical cancer increased with age up until the 75 to 79–year age group and began to decrease at older ages. The Greater Accra region had higher overall incidence and mortality rates than the Ashanti region. …”
Publicado 2016
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2512por Bartonicek, N., Clark, M. B., Quek, X. C., Torpy, J. R., Pritchard, A. L., Maag, J. L. V., Gloss, B. S., Crawford, J., Taft, R. J., Hayward, N. K., Montgomery, G. W., Mattick, J. S., Mercer, T. R., Dinger, M. E.“…Unexpectedly, a large proportion of GWAS single nucleotide polymorphisms (SNPs) and associated haplotype blocks are in intronic and intergenic regions, hindering their functional evaluation. While some of these risk-susceptibility regions encompass cis-regulatory sites, their transcriptional potential has never been systematically explored. …”
Publicado 2017
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2513por Tang, Ying, Winkler, Julie A., Viña, Andrés, Liu, Jianguo, Zhang, Yuanbin, Zhang, Xiaofeng, Li, Xiaohong, Wang, Fang, Zhang, Jindong, Zhao, Zhiqiang“…The uncertainty introduced by the choice of baseline climate information used to calibrate a species distribution model and to downscale global climate model (GCM) simulations to a finer spatial resolution is a particular concern for mountainous regions, as the spatial resolution of climate observing networks is often insufficient to detect the steep climatic gradients in these areas. …”
Publicado 2018
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2514“…The impacts of albinism are particularly serious in areas that associate albinism with legend and folklore, leading to stigmatisation and discrimination. In regions of Africa those with albinism may be assaulted and sometimes killed for their body parts for use in witchcraft-related rites or to make ‘lucky’ charms. …”
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2515“…We find that the direct dust–climate feedback is likely in the range of −0.04 to +0.02 Wm (−2) K(−1), such that it could account for a substantial fraction of the total aerosol feedbacks in the climate system. On a regional scale, the direct dust–climate feedback is enhanced by approximately an order of magnitude close to major source regions. …”
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2516por Madsen, Marianne Sloth, Langen, Peter L., Boberg, Fredrik, Christensen, Jens Hesselbjerg“…Here we use a set of CMIP5 models to show that presenting statistics this way results in an overestimation of the projected range leading to physically implausible patterns of change on global but also on regional scales. We point out that similar inconsistencies occur in impact analyses relying on multimodel information extracted using statistics at the regional scale, for example, when a subset of CMIP models is selected to represent regional model spread. …”
Publicado 2017
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2517por Pande, Amit, Brosius, Jürgen, Makalowska, Izabela, Makalowski, Wojciech, Raabe, Carsten A“…Proximal promoter regions (PPR) are heavily transcribed yielding different types of small RNAs. …”
Publicado 2018
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2518por Raheem, O. A., Floyd, M. S., Casey, R. G., Cullen, I. M., Corcoran, M. O., Bredin, H. C., Walsh, K., OʼRiordan, C., McCarthy, P. A., Rogers, E.Enlace del recurso
Publicado 2009
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2520“…The methylation profile differs significantly among genomic regions. The lowest methylation level was observed for promoter regions, while sites from intergenic regions were by average higher methylated. …”
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