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  1. 437621
    “…This study described and quantified the prescribing of strong opioids, comorbidities and other overdose risk factors among those prescribed strong opioids, and factors associated with high/very high opioid dosage in a regional health authority in Scotland as part of a wider service improvement exercise. …”
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    Quantifying prescribed high dose opioids in the community and risk of overdose
  2. 437622
    “…DNA was extracted and the v1–v9 regions of 16S rRNA were amplified. Subsequently, PacBio sequencing and bioinformatic analyses were performed for microbiome identification. …”
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    The impact of caries status on supragingival plaque and salivary microbiome in children with mixed dentition: a cross-sectional survey
  3. 437623
    “…BACKGROUND: Aedes albopictus is a very invasive mosquito, which has recently colonized tropical and temperate regions worldwide. Of concern is its role in the spread of emerging or re-emerging mosquito-borne diseases. …”
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    Aedes albopictus diversity and relationships in south-western Europe and Brazil by rDNA/mtDNA and phenotypic analyses: ITS-2, a useful marker for spread studies
  4. 437624
    “…Reductions in the GABAergic neurotransmitter system exist across multiple brain regions in schizophrenia and encompass both pre- and postsynaptic components. …”
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    Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia
  5. 437625
    “…Virus-specific primers were derived from conserved regions among randomly selected representatives considering viral genomic diversity. …”
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    One-step real-time multiplex reverse transcription-polymerase chain reaction assay with melt curve analysis for detection of potato leafroll virus, potato virus S, potato virus X, and potato virus Y
  6. 437626
    “…SNPs within ±250kb flanking regions of the transcription start site of 64 genes were examined. …”
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    Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity
  7. 437627
    “…RESULTS: A collection of 118 male sterile rice lines and 13 conventional breeding lines from the major rice growing regions of China was evaluated and screened against the photosensitive (pms3) and temperature sensitive male sterility (tms5) genes. …”
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    Genetic relationships and identification of core germplasm among rice photoperiod- and thermo-sensitive genic male sterile lines
  8. 437628
    “…METHODS: An economic evaluation alongside a 12-month cluster-randomised (1:1) controlled trial conducted between 2017 and 2018 in 25 primary healthcare centres from seven Spanish regions. The study took societal and healthcare provider perspectives. …”
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    Cost-effectiveness analysis of a multiple health behaviour change intervention in people aged between 45 and 75 years: a cluster randomized controlled trial in primary care (EIRA study)
  9. 437629
    “…Epi-cblC disease has accounted for about 13% of cblC cases diagnosed by newborn screening in the Tuscany and Umbria regions since November 2001. Comparative analysis showed that clinical phenotype of epi-cblC patients is similar to that of canonical cblC patients. …”
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    PRDX1 gene-related epi-cblC disease is a common type of inborn error of cobalamin metabolism with mono- or bi-allelic MMACHC epimutations
  10. 437630
    “…While volumetric Magnetic Resonance Imaging scan did not show volume loss in frontotemporal areas, the hybrid scan showed regionally specific deficit in FD-Glucose Positron Emission Tomography affecting medial superior frontal, insula, inferior temporal, thalamus, and anterior cingulate cortex consistent with behavioral variant frontotemporal dementia. …”
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    Schizophrenia syndrome due to C9ORF72 mutation case report: a cautionary tale and role of hybrid brain imaging!
  11. 437631
    “…Furthermore, governance interventions that target entire regions across districts and states combined with decentralised planning are needed. …”
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    An intersectional analysis of the composite index of anthropometric failures in India
  12. 437632
    “…A well-maintained web platform with features such as an encrypted discussion forum, community resource listing, calendar of events, and semi-annual CHN conferences were suggested methods for creating an inter-regional, formal CoP. CONCLUSION: The study findings recognise the presence of an informal CoP within the studied CHN cohort. …”
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    Needs assessment for the creation of a community of practice in a community health navigator cohort
  13. 437633
    “…Besides, Children live in Afar, Amhara, Benishangul-Gumuz, Gambella, SNNPR and Dire Dawa regions had higher incidence of childhood diarrhea. …”
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    Factors associated with childhood diarrheal in Ethiopia; a multilevel analysis
  14. 437634
    “…The distribution of c.615+5G>A and c.1638_1660dup between the 2 provinces, as well as all 4 prevalent mutations among different geographic regions within the 2 provinces, did not differed significantly. …”
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    Molecular epidemiologic study of citrin deficiency by screening for four reported pathogenic SLC25A13 variants in the Shaanxi and Guangdong provinces, China
  15. 437635
    “…Here, we conducted an integrated multi-omics-analysis to unveil the venom-transcriptomic and venomic profiles in a same group of spine-bellied sea snakes (Hydrophis curtus) from the South China Sea, where the snake is a widespread species and might generate regionally-specific venom potentially harmful to human activities. …”
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    Venom-gland transcriptomic, venomic, and antivenomic profiles of the spine-bellied sea snake (Hydrophis curtus) from the South China Sea
  16. 437636
    “…However, all the polymorphic regions in Ethiopian isolates were located away from DARC, responsible for junction formation. …”
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    Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates
  17. 437637
    “…The results emphasize the need for gender-specific analyses as well as an increased attention to the heterogeneity of needs of people with cognitive impairments related to specific wards, settings and regions where they are admitted. Our results indicate also that people with cognitive impairments represent a high proportion of older patients in acute hospital care. …”
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    Describing people with cognitive impairment and their complex treatment needs during routine care in the hospital – cross-sectional results of the intersec-CM study
  18. 437638
    “…Two consecutive steps were identified to effectively use the framework for operational and system planning: (i) development of a ‘module’ outlining the responsibilities and requirements to be delivered at each tier; and (ii) assessment of services provided at the health care facility against those described in the module, alignment to a specific tier, identification of gaps at the local, regional and provincial level, and implementation of quality improvement initiatives to effectively address the gaps. …”
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    Development of the Tiers of Service framework to support system and operational planning for children’s healthcare services
  19. 437639
    “…The presence of ORFs in all three protein-coding regions along with identical 5’ and 3’ LTRs (long terminal repeats) indicate this is a very recent germline acquisition. …”
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    A novel class III endogenous retrovirus with a class I envelope gene in African frogs with an intact genome and developmentally regulated transcripts in Xenopus tropicalis
  20. 437640
    “…RESULTS: We adapted the fitDNM statistical model to work in noncoding regions and tested enhancers for excess of DNVs in families with autism. …”
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    Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism
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