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  1. 437961
    “…In vivo and ex vivo UCL imaging and quantitative analysis revealed that distinctive optical signal was observed in the regions of left carotid common arteries (LCCAs) of AS group after injection of VRBP1-UCNPs. …”
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    Dual-modality Imaging of Angiogenesis in Unstable Atherosclerotic Plaques with VEGFR2-Targeted Upconversion Nanoprobes in vivo
  2. 437962
    “…Amplivant was conjugated to two SLPs derived from the two most immunodominant regions of the HPV16 E6 oncoprotein. The vaccine, containing a mix of these two conjugates in watery solution without any other formulation, was injected intradermally three times with a 3-week interval in four dose groups (1, 5, 20 or 50 µg per conjugated peptide). …”
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    Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions
  3. 437963
    “…METHODS: We consecutively enrolled patients on MHD at the Bamenda Regional, and Yaounde General Hospitals over a period of 3 months. …”
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    Functional status and caregiver burden of patients on maintenance haemodialysis in Cameroon: a two-centre cross-sectional study
  4. 437964
    “…Among all participants, several factors were associated with clinically significant LR for P. falciparum infection, including age 10–14 years (positive LR: 3.73), living in the island district of Douala VI (positive LR: 3.41), travel to any of three northern regions (positive LR: 5.11), and high fever > 40 °C at presentation (positive LR: 4.83). …”
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    Clinical characteristics of Plasmodium falciparum infection among symptomatic patients presenting to a major urban military hospital in Cameroon
  5. 437965
    “…Although many studies have focused on understanding bioactive components in specific sugarcane tissues, crucial questions have been left unanswered about the response of metabolites to niche differentiation such as different sugarcane tissues (leaf, stem and root), and soil regions (rhizosphere and bulk) under silicon (Si) amended soils. …”
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    Niche differentiation modulates metabolites abundance and composition in silicon fertilizer amended soil during sugarcane growth
  6. 437966
    “…Reviews published until September 2020 were retrieved from PubMed, ISI Web of Science, Scopus, Regional Library of Medicine (BIREME), and PsycNET, and from the reference list of selected articles. …”
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    Barriers and facilitators of domain-specific physical activity: a systematic review of reviews
  7. 437967
    “…RESULTS: Participants in this study were 8705 Aboriginal and Torres Strait Islander peoples, with a mean age of 48 years, who primarily live in regional Australia (47.3%). The Mayi Kuwayu Family Functioning Measure demonstrated face validity for family functioning and had good internal consistency/reliability (Cronbach’s alpha > 0.90). …”
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    The development and validation of a family functioning measure for Aboriginal and Torres Strait Islander adults
  8. 437968
    “…Efficacy is reported for patients living in Europe and North America (this cohort completed the study approximately 9 months before the remaining group of patients outside these regions); safety is reported for the full safety dataset, comprising patients living in Europe, North America, and Latin America/Australasia. …”
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    Long-term efficacy and safety of inotersen for hereditary transthyretin amyloidosis: NEURO-TTR open-label extension 3-year update
  9. 437969
    “…METHODS: This cross-sectional, descriptive study employed a mixed-methodsquantitative and qualitative design with a sample of 166 patients that were purposely recruited from in-patient oncology units at a regional teaching hospital in southern Taiwan. Study data consisted of patient replies to a 34-item self-report tool, Decisional Balance, Attitudes, Practice Behaviors of ACP (DAP-ACP) and 4 semi-structured questions. …”
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    The decisional balance, attitudes, and practice behaviors, its predicting factors, and related experiences of advance care planning in Taiwanese patients with advanced cancer
  10. 437970
    “…By removing border labels with MorphoLibJ and detecting regions of interest (ROIs) with LabelsToROIs, the Cellpose–MorphoLibJ–LabelsToROIs (CML) method achieves human-level performance on bright-field images of seed coat cells. …”
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    A simple and efficient method to quantify the cell parameters of the seed coat, embryo and silique wall in rapeseed
  11. 437971
    “…Forty-seven DSDMs located at facilities or community-based points in the four regions of Uganda were included in the study, with 653 adults on ART (> 18 years old) enrolled in a DSDM. …”
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    Similar costs and outcomes for differentiated service delivery models for HIV treatment in Uganda
  12. 437972
    por Ssegujja, Eric, Andipatin, Michelle
    Publicado 2022
    “…BACKGROUND: The current global burden of stillbirth disproportionately affects regions such as sub-Saharan Africa, where Uganda is located. …”
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    Examining the variations in the implementation of interventions to address stillbirth from the national to subnational levels: experiences from Uganda
  13. 437973
    “…The finding underlines the need for improved prescribing accuracy by better understanding regional resistance rates and developing improved diagnostic tests.…”
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    Impact of suboptimal or inappropriate treatment on healthcare resource use and cost among patients with uncomplicated urinary tract infection: an analysis of integrated delivery network electronic health records
  14. 437974
    “…Each of the three models had four NobelSpeedy Replace implants between the interforaminal regions. The two posterior implants were placed 0, 15, and 45 degrees distally before the mental foramen. …”
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    Biomechanical analysis of stress around the tilted implants with different cantilever lengths in all-on-4 concept
  15. 437975
    “…METHODS: The data was extracted from March 2020 to March 2021 from the regional University of Washington Extracorporeal Life Support database. …”
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    Diagnosis and treatment of right ventricular dysfunction in patients with COVID-19 on veno-venous extra-corporeal membrane oxygenation
  16. 437976
    “…The DNA methylation levels at the promoter, first exon and first intron regions were negatively correlated with the expression level of genes at a whole-genome-wide scale. …”
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    Methylome and transcriptome data integration reveals potential roles of DNA methylation and candidate biomarkers of cow Streptococcus uberis subclinical mastitis
  17. 437977
    “…METHODS: In this study, the DNA methylation status of the promoter regions of six imprinted genes, namely potassium voltage-gated channel subfamily Q member 1 (KCNQ1), maternally expressed gene 3 (MEG3), insulin-like growth factor 2 (IGF-2), KCNQ1 overlapping transcript 1 (KCNQ1OT1), mesoderm specific transcript (MEST), and paternally expressed gene 3 (PEG3), were detected by a next generation sequencing-based multiple methylation-specific polymerase chain reaction analysis of sperm samples obtained from 166 men who sought fertility evaluation in our Reproductive Medicine Center. …”
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    Poor semen parameters are associated with abnormal methylation of imprinted genes in sperm DNA
  18. 437978
    por Sun, Delin, Rakesh, Gopalkumar, Haswell, Courtney C., Logue, Mark, Baird, C. Lexi, O’Leary, Erin N., Cotton, Andrew S., Xie, Hong, Tamburrino, Marijo, Chen, Tian, Dennis, Emily L., Jahanshad, Neda, Salminen, Lauren E., Thomopoulos, Sophia I., Rashid, Faisal, Ching, Christopher R.K., Koch, Saskia B.J., Frijling, Jessie L., Nawijn, Laura, van Zuiden, Mirjam, Zhu, Xi, Suarez-Jimenez, Benjamin, Sierk, Anika, Walter, Henrik, Manthey, Antje, Stevens, Jennifer S., Fani, Negar, van Rooij, Sanne J.H., Stein, Murray, Bomyea, Jessica, Koerte, Inga K., Choi, Kyle, van der Werff, Steven J.A., Vermeiren, Robert R.J.M., Herzog, Julia, Lebois, Lauren A.M., Baker, Justin T., Olson, Elizabeth A., Straube, Thomas, Korgaonkar, Mayuresh S., Andrew, Elpiniki, Zhu, Ye, Li, Gen, Ipser, Jonathan, Hudson, Anna R., Peverill, Matthew, Sambrook, Kelly, Gordon, Evan, Baugh, Lee, Forster, Gina, Simons, Raluca M., Simons, Jeffrey S., Magnotta, Vincent, Maron-Katz, Adi, du Plessis, Stefan, Disner, Seth G., Davenport, Nicholas, Grupe, Daniel W., Nitschke, Jack B., deRoon-Cassini, Terri A., Fitzgerald, Jacklynn M., Krystal, John H., Levy, Ifat, Olff, Miranda, Veltman, Dick J., Wang, Li, Neria, Yuval, De Bellis, Michael D., Jovanovic, Tanja, Daniels, Judith K., Shenton, Martha, van de Wee, Nic J.A., Schmahl, Christian, Kaufman, Milissa L., Rosso, Isabelle M., Sponheim, Scott R., Hofmann, David Bernd, Bryant, Richard A., Fercho, Kelene A., Stein, Dan J., Mueller, Sven C., Hosseini, Bobak, Phan, K. Luan, McLaughlin, Katie A., Davidson, Richard J., Larson, Christine L., May, Geoffrey, Nelson, Steven M., Abdallah, Chadi G., Gomaa, Hassaan, Etkin, Amit, Seedat, Soraya, Harpaz-Rotem, Ilan, Liberzon, Israel, van Erp, Theo G.M., Quidé, Yann, Wang, Xin, Thompson, Paul M., Morey, Rajendra A.
    Publicado 2022
    “…Both ComBat and ComBat-GAM outperformed LME methods in detecting sex differences (X(2)(3) = 9.114, p = 0.028) in regional cortical thickness. ComBat-GAM also led to stronger estimates of age-related declines in cortical thickness (corrected p-values < 0.001 ), stronger estimates of case-related cortical thickness reduction (corrected p-values < 0.001 ), weaker estimates of age-related declines in cortical thickness in cases than controls (corrected p-values < 0.001 ), stronger estimates of cortical thickness reduction in females than males (corrected p-values < 0.001 ), and stronger estimates of cortical thickness reduction in females relative to males in cases than controls (corrected p-values < 0.001 ). …”
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    A comparison of methods to harmonize cortical thickness measurements across scanners and sites
  19. 437979
    “…However, there was evidence of disparities in risk by age and/or sex in some WHO regions and in most countries. CONCLUSIONS: There is no evidence at an aggregate global level of any difference by age or sex in the risk of disruption to TB diagnosis as a result of the COVID-19 pandemic. …”
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    Inequalities in the impact of COVID-19-associated disruptions on tuberculosis diagnosis by age and sex in 45 high TB burden countries
  20. 437980
    “…OBJECTIVE: We sought to describe and compare the causes and outcomes of AKI amongst adult patients in Douala general hospital (DGH) and Buea regional hospital (BRH). METHODS: A hospital-based retrospective cohort analytic study was carried from February to April 2021. …”
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    Causes and outcome of acute kidney injury amongst adults patients in two hospitals of different category in Cameroon; a 5 year retrospective comparative study
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