“…Significant methylation differences between CD cases and control subjects were seen by comparing this cohort in conjunction with previously published control data, including validation of our previously described differentially methylated positions (RPS6KA2 P = 1.2 × 10(-19), SBNO2 = 1.2 × 10(-11)) and regions (TXK [false discovery rate, P = 3.6 × 10(-14)], WRAP73 [false discovery rate, P = 1.9 × 10(-9)], VMP1 [false discovery rate, P = 1.7 × 10(-7)], and ITGB2 [false discovery rate, P = 1.4 × 10(-7)]). …”
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“…BACKGROUND AND OBJECTIVES: The objective of this study was to examine whether the regional methylation levels at the most distal D4Z4 repeat units (RU) in the 4qA-permissive haplotype were associated with disease severity and progression in facioscapulohumeral muscular dystrophy type 1 (FSHD1). …”
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“…Pathologist review of image-based heatmaps suggests that nuclear size pleomorphism, intense cellularity, and abnormal structures are associated with high-risk, while low-risk regions have more regular and small cells. Quantitative analysis shows high cellularity, high ratios of tumor cells, large tumor nuclei, and low immune infiltration are indicators of high-risk tiles. …”
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“…Regional lymph node metastasis (LNM) is a competent and the most intensive predictor for the prognostic evaluation of patients after curative surgery. …”
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“…The survey results were presented primarily as frequencies of responses and were evaluated by the respondent’s plan size, type, and geography (regional vs national). Differences in responses for categorical data were compared using a Pearson Chi-Square or a Fisher’s Exact test. …”
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“…OBJECTIVE: To examine the use of PAPs among patients with multiple sclerosis (MS) and the association with drug demand in a specialty pharmacy program within a regional integrated health system that facilitates their use. …”
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“…METHODS: The web-based survey was completed by creating questionnaires and using a stratified random sampling method to collect information from adults (≥18 years old) among 2556 households in 4 geographical regions of China. We collected sociodemographic information, health status, awareness of COVID-19 and its vaccine, self-perceptions, trust in medical staff and vaccine developers, and so on. …”
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“…Comparative analyses were performed on data about deaths, DALYs and the responding ASRs attributable to unsafe sex in different countries and regions using the Social Demographic Index (SDI). …”
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“…This intervention should be tested across different regions and clinical settings to verify the findings. …”
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“…The midpoint of the line between the foramen magnum and the end of the right acromion served as measuring point. Regions of interest were scaled to span 0–8.0 m/s. …”
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“…On the basis of the findings and conceptual framework gained from the qualitative interviews, a cross-sectional, anonymous, web-based survey of 593 medical practitioners in 28 provincial administrative regions of China was conducted. The data collected were analyzed using the partial least squares method, with the assistance of SPSS 27.0 (IBM Corp) and Mplus 7.0 (Muthen and Muthen), to measure and validate the proposed model. …”
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“…Participants with A(−) TMTL(+) had accelerated MTL atrophy, whereas those with A(+) TMTL(+) showed accelerated atrophy in widespread temporoparietal brain regions. Increased MTL tau PET uptake in A(−) individuals was associated with cognitive decline, but at a significantly slower rate compared with A(+) TMTL(+). …”
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“…As part of this study, we conducted a quantitative analysis in young adults 16 to 30 years of age in two regions of Chile between August and October, 2022. …”
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“…CONCLUSIONS: In depressive patients who underwent COVID-19, the severity of suicidal intentions is associated with EEG signs of a more reduced functional state of the cerebral cortex, including the anterior regions, than in patients who did not have coronavirus infection. …”
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“…This study aimed to investigate the use of injection MMC as a local application on surgical resection beds for patients undergoing surgery for oral cancer and to assess its efficacy in preventing regional recurrences. Methodology In this prospective, interventional, pilot study, patients were assigned randomly to two groups using simple randomization. …”
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“…Research is also needed to address geographical inequalities at the regional and national level. Important questions also remain on the quality of the available research—is child and adolescent MHPSS intervention research locally relevant, reliable, well‐designed and conducted, accessible and innovative? …”
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“…We identified fluctuating temporal dynamics of ESC-R-Ec infections, which have also recently been identified in other geographical regions such as Israel. Our WGS data allowed us to visualize the stable nature of STc131 over the study period and demonstrate a limited but genetically diverse group of ESC-R-Ec clonal complexes are detected during infection peaks. …”
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“…CONCLUSIONS: Due to our system’s fast and minimalistic nature, it may make a worthwhile contribution to identifying depression in underdeveloped and developing regions. In addition, our detailed discussion about the implication of our findings can facilitate the development of less resource-intensive systems to better understand students who are depressed and take steps for intervention.…”
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“…There was no difference in use of telehealth between metropolitan and nonmetropolitan regions; however, people with a bachelor’s degree or above were more likely to have used telehealth and to report a positive experience. …”
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