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  1. 438321
    “…Primers were designed from highly common conserved regions of the major HTLV-1 subtypes to characterize the entire HTLV-1 proviral genome. …”
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    A Novel Human T-lymphotropic Virus Type 1c Molecular Variant in an Indigenous Individual from New Caledonia, Melanesia
  2. 438322
    “…Both CSF Aβ43 and Aβ42 were negatively correlated with standardized uptake value ratios for all analyzed regions; CSF Aβ43 average rho -0.73, Aβ42 -0.74. Both CSF Aβ peptides correlated significantly with hippocampal volume, inferior parietal and frontal cortical thickness and axial diffusivity in the corticospinal tract. …”
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    Cerebrospinal Fluid Levels of Amyloid Beta 1-43 Mirror 1-42 in Relation to Imaging Biomarkers of Alzheimer’s Disease
  3. 438323
    “…In this context, we showed regional co-localization of JAB1 with p38 MAPK in atherosclerotic plaques of ApoE(−/−) mice. …”
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    Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation
  4. 438324
    “…Following histological assessment, tumour-rich regions of formalin-fixed paraffin-embedded (FFPE) sections underwent macrodissection, DNA extraction, NGS, and analysis using a pipeline centred on Torrent Suite software. …”
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    Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service
  5. 438325
    “…BACKGROUND: In a previously reported study, patients with regionally advanced melanoma were treated with neoadjuvant ipilimumab (ipi) (Tarhini in PLoS ONE 9(2): e87705, 3). …”
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    Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab
  6. 438326
    “…BACKGROUND: The Australian paralysis tick, Ixodes holocyclus, causes paralysis predominantly in dogs and cats in the Eastern coastal regions of Australia. Rapid onset of effect of a parasiticide is critical to minimize the deleterious effects of these tick infestations, especially tick paralysis caused by the salivary neurotoxin. …”
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    Comparative speed of kill of sarolaner (Simparica(®)) and afoxolaner (NexGard(®)) against induced infestations of Ixodes holocyclus on dogs
  7. 438327
    “…Forty patients were randomized 1:1 to treatment with serelaxin intravenous (i.v.) infusion (for 60 min at 80 μg/kg/d and then 60 min at 30 μg/kg/d) or terlipressin (single 2-mg i.v. bolus), and the regional hemodynamic effects were quantified by phase contrast magnetic resonance angiography at baseline and after 120 min. …”
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    Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial
  8. 438328
    “…Putative promoters in the intergenic regions upstream the kstD1, kstD2 and kstD3 genes were identified and probed in an apramycin-promoter-test vector, leading to the functional evidence of those R. ruber kstD promoters. …”
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    Functional differentiation of 3-ketosteroid Δ(1)-dehydrogenase isozymes in Rhodococcus ruber strain Chol-4
  9. 438329
    “…METHODS: A pragmatic, two-armed randomised controlled, open feasibility study of PWID attending drug treatment or IEP in four UK regions. Ninety-nine PWID were randomly allocated to receive a three-session manualised psychosocial group intervention and BBV transmission information booklet plus treatment as usual (TAU) (n = 52) or information booklet plus TAU (n = 47). …”
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    The acceptability and feasibility of a brief psychosocial intervention to reduce blood-borne virus risk behaviours among people who inject drugs: a randomised control feasibility trial of a psychosocial intervention (the PROTECT study) versus treatment as usual
  10. 438330
    “…Immunofluorescence analysis demonstrated that PvMSA180 is localized on the merozoite surface of schizont-stage parasites, and pvmsa180 sequences originating from various geographic regions worldwide showed low genetic diversity. Twenty-two haplotypes were found, and haplotype 6 (Hap_6, 77%) of pvmsa180 was detected in isolates from six countries. …”
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    Identification of a novel merozoite surface antigen of Plasmodium vivax, PvMSA180
  11. 438331
    “…Our study showed that despite normal systolic function, patients with Wilson’s disease showed diastolic dysfunction and regional deformation abnormalities, especially rotational strain and strain rate abnormalities.…”
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    Strain and strain rate echocardiography in children with Wilson’s disease
  12. 438332
    “…Further analysis of the map regions with the highest LOD scores enabled the identification of putative genes that could be associated with the fruit quality characteristics. …”
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    QTL mapping for fruit quality in Citrus using DArTseq markers
  13. 438333
    “…These data, along with findings from two retrospective studies, support use of oral cholera vaccine in pregnant women in cholera-affected regions. FUNDING: Bill & Melinda Gates Foundation.…”
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    Safety of a killed oral cholera vaccine (Shanchol) in pregnant women in Malawi: an observational cohort study
  14. 438334
    “…RESULTS: In this study, eight StSnRK2 genes (StSnRK2.1- StSnRK2.8) were identified in the genome of the potato (Solanum tuberosum L.) cultivar ‘Longshu 3’, with similar characteristics to SnRK2 from other plant species in gene structure, motif distribution and secondary structures. The C-terminal regions were highly divergent among StSnRK2s, while they all carried the similar Ser/Thr protein kinase domain. …”
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    Sucrose non-ferment 1 related protein kinase 2 (SnRK2) genes could mediate the stress responses in potato (Solanum tuberosum L.)
  15. 438335
    “…Stonechats are highly seasonal breeders at all these sites, but vary between tropical and temperate regions with regard to reproductive investment and presumably also survival. …”
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    Baseline and stress-induced levels of corticosterone in male and female Afrotropical and European temperate stonechats during breeding
  16. 438336
    “…Buccal swabs were collected for DNA methylation analysis of three regions (six CpG sites) in the FOXP3 promoter. RESULTS: In multivariable regression models, overall, there was no significant relationship between physical activity and FOXP3 promoter methylation (p > 0.05). …”
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    Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter
  17. 438337
    “…HHV8 viral load and expression profiles of latent (ORF72 and ORF73) and lytic (K2, K8, K8.1, K10/K10.1, K10.5/K10.6 and ORF16) genes were assessed in all samples by real-time PCR. HHV8 ORF26 and K1 regions were amplified and subjected to direct nucleotide sequencing followed by phylogenetic analysis for variant identification. …”
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    Effect of electrochemotherapy on human herpesvirus 8 kinetics in classic Kaposi sarcoma
  18. 438338
    “…Additionally, during acute infection, most infected cells appeared to be anatomically distributed within the OB rather than other regions of the CNS. During latency (i.e., 30 DPI and beyond) despite no detectable infectious virus or lytic gene expression and low levels of latency associated transcripts, total effector (CD44(+) CD62(−)) CD4(+) T, CD8(+) T, HSV-1-specific CD8(+) T cells, and MHC class II positive resident microglia numbers continued to increase. …”
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    Herpes simplex virus-1 infects the olfactory bulb shortly following ocular infection and exhibits a long-term inflammatory profile in the form of effector and HSV-1-specific T cells
  19. 438339
    “…CONCLUSION: Immunization status (89.5%) and coverages ranged 92 to 99% of the vaccine doses is high compared to national and regional. Problems of not fully immunized persists and needs urgent attention. …”
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    Evaluation of immunization coverage and its associated factors among children 12–23 months of age in Techiman Municipality, Ghana, 2016
  20. 438340
    “…We studied associations between NfL concentrations in plasma and clinical and MRI neuroimaging findings, namely cognitive function, motor function, and brain volume (global and regional). We used random effects models to analyse cross-sectional associations at each study visit and to assess changes from baseline, with and without adjustment for age and CAG repeat count. …”
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    Neurofilament light protein in blood as a potential biomarker of neurodegeneration in Huntington's disease: a retrospective cohort analysis
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