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  1. 438821
    “…The phylogenetic analysis revealed that the majority of the variants occurred in highly conserved regions. The MD simulation analysis exhibited that all mutants’ average root mean square deviation (RMSD) values were higher compared to the wild-type protein, which could potentially cause CYP1B1 protein dysfunction, leading to the severity of the disease. …”
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    Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach
  2. 438822
    “…[Figure: see text] [Figure: see text] CONCLUSION: Important regional differences are noted for ESBL + and ≥ 3 drug resistance to urine isolates in the OP setting complicating oral antibiotic therapy. …”
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    2237. Enterbacterales Resistance Patterns for Extended-spectrum beta-lactamases (ESBL) Positive and Multidrug Resistance (MDR) Urine Isolates Collected and Tested from 295 Outpatient US Facilities in 2019
  3. 438823
    “…A set of 10 miRNAs were selected via an in silico approach by analysing the 3’untranslated regions (3’UTRs) of cancer-related mRNAs such as FLRT2, NTRK3, and SLC8A1, TFCP2L1 and etc. …”
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    A novel panel of clinically relevant miRNAs signature accurately differentiates oral cancer from normal mucosa
  4. 438824
    “…Equine owners, with on farm equids from the southern US were WTP 11% less than from other regions (P = 0.015). The current boarding fees from owners that board their equids lowered their WTP by 0.01% (P = 0.029) for each additional dollar paid, whereas current care costs were not a significant factor for other owners (P = 0.370) or leasers (P = 0.395). …”
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    124  Financial strain caused by COVID-19 and its impact on equine industry participant willingness-to-pay for equine care
  5. 438825
    “…The questionnaire consisted of closed-ended, 7-point Likert scale questions and multiple choice questions and was distributed to all over Greek Regions to almost 3.000 recipients, during the implementation of restrictive measures against the COVID-19 outbreak in Spring 2020. …”
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    Information seeking behavior and COVID-19 pandemic: A snapshot of young, middle aged and senior individuals in Greece
  6. 438826
    “…All patients underwent planar whole-body scans and subsequent SPECT/CT of the thoracic and abdominal regions after intravenous injection of 705 ± 70 MBq of 99mTc-HYNIC-PSMA. …”
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    Diagnostic performance of 99mTc-HYNIC-PSMA SPECT/CT for biochemically recurrent prostate cancer after radical prostatectomy
  7. 438827
    “…MCAO upregulated NCX3 gene expression in the core, penumbra, and subcortical regions compared with the intact subgroup. The V5 subgroup significantly downregulated the NCX3 gene expression level in the core compared with the control subgroup. …”
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    Protective Effect of the Viola spathulata Extract on NCX3 Gene Expression in an Animal Model of Cerebral Ischemia
  8. 438828
    “…We also identified common statistical issues and knowledge gaps that remain to be addressed in future research, such as a high rate of pseudoreplication and multiple unexplored combinations of metrics, taxa, and regions. Our findings confirm the limitations of acoustic indices to efficiently quantify alpha biodiversity and highlight that caution is necessary when using them as surrogates of diversity metrics, especially if employed as single predictors. …”
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    Acoustic indices as proxies for biodiversity: a meta‐analysis
  9. 438829
    “…Our results identify regions where targeted public health efforts could have been most effective and suggest that individuals’ frequency of mask-wearing may be influenced by national guidance and disease prevalence. …”
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    Spatiotemporal trends in self-reported mask-wearing behavior in the United States: Analysis of a large cross-sectional survey
  10. 438830
    “…Several periods of stress and permanent stress were reported for 2745 cases (20.5%) and 1933 controls (14.4%), with marked regional variation in prevalence, with the lowest in China (201 of 3981 [5.0%] among controls and 364 of 3980 [9.1%] among cases) and highest in South East Asia (233 of 855 [26.1%] among controls and 241 of 782 [30.8%] among cases). …”
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    Association of Psychosocial Stress With Risk of Acute Stroke
  11. 438831
    “…Ticks and tick-borne diseases are considered a major challenge for human and animal health in tropical, sub-tropical, and temperate regions of the world. However, only scarce information is available on the characterization of tick species infesting dogs in Pakistan. …”
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    Ticks Infesting Dogs in Khyber Pakhtunkhwa, Pakistan: Detailed Epidemiological and Molecular Report
  12. 438832
    “…The federal government should balance the proportion of anemia among regions by ensuring health equality.…”
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    Trend and factors associated with anemia among women reproductive age in Ethiopia: A multivariate decomposition analysis of Ethiopian Demographic and Health Survey
  13. 438833
    “…The offline data include 9 years (2006-2014) of medical resource statistics of 31 provincial administrative regions in mainland China. Moreover, data regarding the geolocation-based physician-patient interaction network in the OHC were also collected. …”
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    The Effect of Offline Medical Resource Distribution on Online Physician-Patient Interaction: Empirical Study With Online and Offline Data
  14. 438834
    “…Even though the white population had the highest overall prevalence of childhood obesity (40.9%), the Hispanic and black people had a higher prevalence per population, with a 0.5% and 0.33% prevalence, respectively, compared to 0.14% in the white population (p < 0.0001). When geographical regions were considered, south had the highest rate (36.40%), followed by the west (24.71%) and the midwest (23.56%). …”
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    Obesity in the Pediatric Population of the National (Nationwide) Inpatient Sample (NIS), USA
  15. 438835
    “…A subset of 157 children had EEG performed at age 18 months; EEG relative theta power and theta/beta ratio at the frontocentral and parietal regions showed a graded correlation with 12-month screen use (r = 0.35-0.37). …”
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    Associations Between Infant Screen Use, Electroencephalography Markers, and Cognitive Outcomes
  16. 438836
    “…This rigorous Delphi process that combined evidence, consumer expert opinion and topic expert consensus can inform similar initiatives in countries/regions lacking consensus on sarcopenia.…”
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    Consensus guidelines for sarcopenia prevention, diagnosis and management in Australia and New Zealand
  17. 438837
    “…Type 1, 2, and 3 patients (with at least two anchoring regions) will receive TAVR with a transcatheter heart valve (THV), but Type 4 patients (with zero or one anchoring location) will be deemed unsuitable for TAVR and will instead receive medical care (retrospectively enrolled patients who already underwent TAVR are an exception). …”
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    Can Measuring the ‘Dual Anchors of Aorta’ Enhance the Success Rate of TAVR?—A Single-Center Experience
  18. 438838
    “…GlobalConsent shows promise for national scale-up and regional adaptations. TRIAL REGISTRATION: ClinicalTrials.gov NCT04147455; https://clinicaltrials.gov/ct2/show/NCT04147455 INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/s12889-020-09454-2…”
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    Impacts of GlobalConsent, a Web-Based Social Norms Edutainment Program, on Sexually Violent Behavior and Bystander Behavior Among University Men in Vietnam: Randomized Controlled Trial
  19. 438839
    “…BACKGROUND: The WHO recommended 1200mg/day of fluconazole (FCZ) in the induction phase of cryptococcal meningitis (CM) in HIV prior to 2018 in regions where amphotericin-B (AMB) was unavailable. …”
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    Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis (HIFLAC)—report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group
  20. 438840
    “…Furthermore, persistent strains showed loss, acquisition, or genetic changes in prophage-associated regions. Long-term azithromycin therapy results in macrolide resistance, as well as genetic changes that likely favor bacterial adaptation during persistent respiratory colonization. …”
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    Genetic Adaptation and Acquisition of Macrolide Resistance in Haemophilus spp. during Persistent Respiratory Tract Colonization in Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Long-Term Azithromycin Treatment
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