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“…We highlight the common mechanisms of ALA’s renal protective actions that include decreasing oxidative damage, increasing antioxidant capacities, counteracting inflammation, mitigating renal fibrosis, and attenuating nephron cell death. …”
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“…METHODS: Here, we further explored in rats 8-aminoguanine’s effects on renal excretory function by combining studies using intravenous 8-aminoguanine, intrarenal artery infusions of PNPase substrates (inosine and guanosine), renal microdialysis, mass spectrometry, selective adenosine receptor ligands, adenosine receptor knockout rats, laser doppler blood flow analysis, cultured renal microvascular smooth muscle cells, HEK293 cells expressing A(2B) receptors and homogeneous time resolved fluorescence assay for adenylyl cyclase activity. …”
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“…Renal biopsy pathology is an essential gold standard for the diagnosis of most kidney diseases. …”
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“…Renal coloboma syndrome is an autosomal dominant genetic disorder that primarily affects kidney and eye development. …”
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“…Background: Survival in patients with end-stage kidney disease (ESKD) on renal replacement therapy (RRT) is less than that of the general population of the same age, and depends on patient factors, the medical care received, and the type of RRT used. …”
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“…SIMPLE SUMMARY: Over the last decade there has been a significant increase in the number of therapies that activate the host’s immune system to target and eliminate renal cell carcinoma (RCC) tumors. The superior efficacy of these agents demonstrates that host control of RCC requires a robust and effective immune response. …”
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“…Renal cell carcinoma (RCC) is a common genitourinary cancer. …”
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“…Glomerulonephritis are renal disorders resulting from different pathogenic mechanisms (i.e., autoimmunity, complement, inflammatory activation, etc.). …”
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“…Apart from increased fluid intake, patients with kidney stone disease (KSD) due to renal phosphate wasting require specific metaphylaxis. …”
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“…Our finding links expression of one of the main regulators of accurate renal development with the hypoxia signalling pathway and provides additional insight into the pathophysiology of polycystic kidney disease.…”
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“…Whether AKI is induced by chemotoxicity or hyperthermia-related changes in renal perfusion remains controversial. The influence of HIPEC on renal perfusion has not been evaluated in patients yet. …”
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“…This study aimed to identify renal dysfunction in candidates for bariatric surgery. …”
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“…A differential diagnosis of renal cell carcinoma, lymphoma, retroperitoneal fibrosis (RPF), and IgG4 renal disease was suggested on imaging studies and biopsy of the mass. …”
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“…OBJECTIVE: Mutation of p53 is detected in more than 50% of human cancers, expression of p53 has a potential prognostic value in patients with renal cell carcinoma (RCC). Survivin is a member of the inhibitor of apoptosis protein family, its overexpression is observed in many malignancies, including RCC. …”
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