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98041por Nangaku, Masaomi, Kanda, Hironori, Takama, Hirotaka, Ichikawa, Tomohiro, Hase, Hiroki, Akizawa, Tadao“…However, the phase 3 study, Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes Mellitus: the Occurrence of Renal Events (BEACON), was terminated prematurely because bardoxolone methyl increased the risk for early-onset fluid overload in patients with identifiable risk factors for heart failure (elevated baseline B-type natriuretic peptide levels >200 pg/ml and prior history of hospitalization for heart failure). …”
Publicado 2020
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98042“…For the four models derived, these are: (1) for hospitalization: age, gender, chronic renal insufficiency, diabetes, immunosuppression; (2) for mortality: age, SARS-CoV-2 test status, immunosuppression and pregnancy; (3) for ICU need: development of pneumonia (if available), cardiovascular disease, asthma, and SARS-CoV-2 test status; and (4) for ventilator need: ICU and pneumonia (if available), age, gender, cardiovascular disease, obesity, pregnancy, and SARS-CoV-2 test result.…”
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98043por Ndwiga, Charity, Odwe, George, Pooja, Sripad, Ogutu, Omondi, Osoti, Alfred, E. Warren, Charlotte“…Women with EO-PE compared to LO-PE had greater odds of adverse maternal and perinatal outcomes including hemolysis elevated liver enzymes and low platelets (HELLP) syndrome (OR: 4.3; CI 2.0–10.2; p<0.001), renal dysfunction (OR; 1.7; CI 0.7–4.1; p = 0.192), stillbirth (OR = 4.9; CI 3.1–8.1; p<0.001), and neonatal death (OR: 8.5; CI 3.8–21.3; p<0.001). …”
Publicado 2020
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98044por Heldwein, Flavio Lobo, Loeb, Stacy, Wroclawski, Marcelo Langer, Sridhar, Ashwin Narasimha, Carneiro, Arie, Lima, Fabio Sepulveda, Teoh, Jeremy Yuen-Chun“…There was consensus on postponing radical prostatectomy except for high-risk prostate cancer, and delaying treatment for low-grade bladder cancer, small renal masses up to T2, and stage I seminoma. According to nine guidelines that addressed endourology, obstructed or infected kidneys should be decompressed, whereas nonobstructing stones and stent removal should be rescheduled. …”
Publicado 2020
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98045por Mezzetti, Matteo, Minuti, Andrea, Bionaz, Massimo, Piccioli-Cappelli, Fiorenzo, Trevisi, Erminio“…SIMPLE SUMMARY: This study highlights the positive effect of an Aloe arborescens Mill. whole plant homogenate on the liver and renal function of dairy cows during the peripartum period. …”
Publicado 2020
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98046por Kwon, Oh Chan, Park, Jung Hwan, Park, Hyeong-Cheon, Jung, Seung Min, Lee, Sang-Won, Song, Jason Jungsik, Park, Yong-Beom, Park, Min-Chan“…BACKGROUND: To investigate non-histologic factors that can discriminate proliferative lupus nephritis (LN) from membranous LN in patients with systemic lupus erythematosus with renal manifestations. METHODS: Patients with biopsy-proven proliferative LN (class III ± V and class IV ± V) and membranous LN (class V) were included. …”
Publicado 2020
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98047“…BACKGROUND: It has been estimated that automated peritoneal dialysis (APD) is currently the fastest growing renal replacement therapy in the world. However, in light of the growing number of diabetic patients on peritoneal dialysis (PD), the unwanted glucose absorption during APD remains problematic. …”
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98048por Jung, Hee-Yeon, Jeon, Yena, Seong, Sook Jin, Seo, Jung Ju, Choi, Ji-Young, Cho, Jang-Hee, Park, Sun-Hee, Kim, Chan-Duck, Yoon, Young-Ran, Yoon, Se-Hee, Lee, Jong Soo, Kim, Yong-Lim“…The intrapatient variability of tacrolimus and mycophenolic acid levels, renal function, and adverse transplant outcomes did not differ between the intervention and control groups, or between the intervention group with feedback generation and the intervention group without feedback generation. …”
Publicado 2020
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98049por Lee, Cheol Hyun, Choi, Sang-Woong, Jun, Seung-Woon, Hwang, Jongmin, Kim, In-Cheol, Cho, Yun-Kyeong, Park, Hyoung-Seob, Yoon, Hyuck-Jun, Kim, Hyungseop, Nam, Chang-Wook, Han, Seongwook, Kim, Kwon-Bae, Hur, Seung-Ho“…In multivariate analyses, the presence of DM and renal failure were strong predictors of MACE and target-vessel revascularization (TVR). …”
Publicado 2020
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98050por Koliaki, Chrysi, Tzeravini, Evangelia, Papachristoforou, Eleftheria, Severi, Ioanna, El Deik, Elina, Karaolia, Melina, Noutsou, Marina, Thanopoulou, Anastasia, Kountouri, Aikaterini, Balampanis, Konstantinos, Lambadiari, Vaia, Tentolouris, Nicholas, Kokkinos, Alexander“…Eligible patients are younger and more obese, have a shorter T2DM duration, worse glycaemic control and better renal function, compared to non-eligible ones. Among eligible patients, only 39.3% have been medically informed about the option of BS. …”
Publicado 2020
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98051por Shi, Jikang, Cheng, Zhaorui, Qiu, Shuang, Cui, Heran, Gu, Yulu, Zhao, Qian, Ren, Yaxuan, Zhang, He, Sun, Helin, Liu, Yunkai, Li, Yong, Qiao, Yichun, Hu, Yueyang, Liu, Yawen, Cheng, Yi“…BACKGROUND: Diabetic nephropathy (DN) contributes to end-stage renal failure. Microvascular injury resulted from reactive oxygen species is implicated in the pathogenesis of DN. …”
Publicado 2020
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98052por Douwes, Rianne M., Gomes-Neto, António W., Eisenga, Michele F., Van Loon, Elisabet, Schutten, Joëlle C., Gans, Rijk O. B., Naesens, Maarten, van den Berg, Else, Sprangers, Ben, Berger, Stefan P., Navis, Gerjan, Blokzijl, Hans, Meijers, Björn, Bakker, Stephan J. L., Kuypers, Dirk“…These findings were replicated in the Leuven Renal Transplant Cohort. The main limitation of this study is its observational design, which precludes conclusions about causation. …”
Publicado 2020
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98053por Jhee, Jong Hyun, Joo, Young Su, Han, Seong Hyeok, Yoo, Tae‐Hyun, Kang, Shin‐Wook, Park, Jung Tak“…CONCLUSIONS: Lower fat mass relative to muscle mass may lower the risk of CKD development in individuals with normal renal function. This relationship seems more prominent in overweight and obese subjects than in normal weight subjects.…”
Publicado 2020
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98054por Prescott, Sean, Traynor, Jamie P., Shilliday, Ilona, Zanotto, Tobia, Rush, Robert, Mercer, Thomas H.“…METHODS: Seventy people receiving maintenance haemodialysis (age 55.9 ± 15.7 years, 34% women, 23% diabetic) from a single outpatient renal unit volunteered for the study. Participants wore Actigraph GT3x and ActivPAL monitors during waking hours over seven days. …”
Publicado 2020
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98055por Nandagopal, Nithyashree, Reddy, Pavan K, Ranganathan, Lakshmi, Ramakrishnan, Nagarajan, Annigeri, Rajiv, Venkataraman, Ramesh“…There was a higher need for renal replacement therapy (RRT) among patients with septic AKI in comparison to those with nonseptic AKI (19.3% vs 6.1%; p = 0.04), but no mortality difference was seen between the two groups (25.8% vs 20.4%, p = 0.5). …”
Publicado 2020
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98056por Maddirevula, Sateesh, Kuwahara, Hiroyuki, Ewida, Nour, Shamseldin, Hanan E., Patel, Nisha, Alzahrani, Fatema, AlSheddi, Tarfa, AlObeid, Eman, Alenazi, Mona, Alsaif, Hessa S., Alqahtani, Maha, AlAli, Maha, Al Ali, Hatoon, Helaby, Rana, Ibrahim, Niema, Abdulwahab, Firdous, Hashem, Mais, Hanna, Nadine, Monies, Dorota, Derar, Nada, Alsagheir, Afaf, Alhashem, Amal, Alsaleem, Badr, Alhebbi, Hamoud, Wali, Sami, Umarov, Ramzan, Gao, Xin, Alkuraya, Fowzan S.“…Definitive results from RT-PCR are obtained from blood-derived RNA for the overwhelming majority of variants (84.1%), and only a small minority (2.6%) fail analysis on all available RNA sources (blood-, skin fibroblast-, and urine renal epithelial cells-derived), which has important implications for the clinical application of RNA-seq. …”
Publicado 2020
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98057por Liu, Yang, Lin, Yao, Zhang, Ming-Ming, Li, Xiao-Hui, Liu, Yan-Yan, Zhao, Jing, Shi, Lin“…Data on indicators were used for assessing cardiac and renal damages. The correlations of plasma renin, angiotensin, and aldosterone (RAAS) levels to blood pressure variability (BPV) and target organ damage (TOD) were studied. …”
Publicado 2020
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98058por Chen, Fang-Ting, Chen, Shao-Wei, Wu, Victor Chien-Chia, Hung, Kuo-Chun, Chang, Shang-Hung, Ting, Pei-Chi, Chou, An-Hsun“…MAIN OUTCOME MEASURES: The outcomes included in-hospital major complications/mortality, all-cause mortality, cardiovascular death, newly onset end-stage renal disease and respiratory failure during the follow-up period. …”
Publicado 2020
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98059por Abbasi Dezfouli, Sepehr, Nikdad, Mohammadsadegh, Ghamarnejad, Omid, Khajeh, Elias, Arefidoust, Alireza, Mohammadi, Sara, Majlesara, Ali, Sabagh, Mohammadsadegh, Gharabaghi, Negin, Kentar, Modar, Younsi, Alexander, Eckert, Christoph, Poth, Tanja, Golriz, Mohammad, Mehrabi, Arianeb, Nickkholgh, Arash“…The aim of this project is to investigate the effects of (oral) donor preconditioning with a calcineurin inhibitor (Cyclosporine) vs. an inhibitor of mammalian target for Rapamycin (Everolimus) compared to the conventional administration of steroid in the setting of donation after brain death in porcine renal transplantation. Methods: Six hours after the induction of brain death, German landrace donor pigs (33.2 ± 3.9 kg) were randomly preconditioned with either Cyclosporine (n = 9) or Everolimus (n = 9) administered via nasogastric tube with a repeated dose just before organ procurement. …”
Publicado 2020
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98060“…A comprehensive comparison of the effectiveness of the two courses of treatment revealed that patients in group 1 demonstrated a higher improvement ratio (P < 0.01) and lower worsening ratio of the neurological symptoms for the patients (P < 0.01) in comparison to the patients in group 2. Meanwhile, renal function, liver enzyme and blood cell counts remained stabilized in group1. …”
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