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98541por Curtis, Helen J, MacKenna, Brian, Walker, Alex J, Croker, Richard, Mehrkar, Amir, Morton, Caroline, Bacon, Seb, Hickman, George, Inglesby, Peter, Bates, Chris, Evans, David, Ward, Tom, Cockburn, Jonathan, Davy, Simon, Bhaskaran, Krishnan, Schultze, Anna, Rentsch, Christopher T, Williamson, Elizabeth, Hulme, William, Tomlinson, Laurie, Mathur, Rohini, Drysdale, Henry, Eggo, Rosalind M, Wong, Angel Yun, Forbes, Harriet, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian, Smeeth, Liam, Goldacre, Ben“…Factors associated with switching included: older age, recent renal function test, higher number of recent INR tests recorded, atrial fibrillation diagnosis and care home residency. …”
Publicado 2021
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98542por Lonial, Sagar, Lee, Hans C., Badros, Ashraf, Trudel, Suzanne, Nooka, Ajay K., Chari, Ajai, Abdallah, Al‐Ola, Callander, Natalie, Sborov, Douglas, Suvannasankha, Attaya, Weisel, Katja, Voorhees, Peter M., Womersley, Lynsey, Baron, January, Piontek, Trisha, Lewis, Eric, Opalinska, Joanna, Gupta, Ira, Cohen, Adam D.“…Response and survival outcomes in patients who had high‐risk cytogenetics or renal impairment were consistent with outcomes in the overall population. …”
Publicado 2021
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98543por Du, Hao, Siah, Kewin Tien Ho, Ru-Yan, Valencia Zhang, Teh, Readon, En Tan, Christopher Yu, Yeung, Wesley, Scaduto, Christina, Bolongaita, Sarah, Cruz, Maria Teresa Kasunuran, Liu, Mengru, Lin, Xiaohao, Tan, Yan Yuan, Feng, Mengling“…The individual performances of the models were compared against current severity scores (Clostridiodes difficile Associated Risk of Death Score (CARDS) and ATLAS (Age, Treatment with systemic antibiotics, leukocyte count, Albumin and Serum creatinine as a measure of renal function) by calculating area under receiver operating curve (AUROC). …”
Publicado 2021
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98544por Zhao, Huiying, Kennedy, Jason N., Wang, Shu, Brant, Emily B., Bernard, Gordon R., DeMerle, Kimberley, Chang, Chung-Chou H., Angus, Derek C., Seymour, Christopher W.“…In the host model, alpha type (N = 327, 19%) was younger and had less shock; beta type (N=518, 31%) was older with more comorbidities; gamma type (N = 532, 32%) had more pulmonary dysfunction; delta type (N = 313, 19%) had more liver, renal and hematologic dysfunction and shock. After the addition of microbiologic variables, 772 (46%) patients changed phenotype membership, and the median probability of phenotype membership increased from 0.95 to 0.97 (P < 0.01). …”
Publicado 2021
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98545por Kronig, Ilona, Masouridi-Levrat, Stavroula, Chalandon, Yves, Glampedakis, Emmanouil, Vernaz, Nathalie, Van Delden, Christian, Neofytos, Dionysios“…RESULTS: Among 30 identified patients, the indications for isavuconazole administration were adverse events associated with prior antifungal treatment (N: 18, 60%: hepatotoxicity, renal insufficiency, long QTc interval, neurotoxicity, and potential drug–drug interactions in 6, 4, 3, 1 and 4 patients, respectively), clinical efficacy (N: 5, 16.6%), and other reasons (N: 10, 33.3%; 5/10 patients treated with isavuconazole to facilitate hospital discharge with orally administered appropriate treatment). …”
Publicado 2021
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98546por Wenzel, Jan-Per, Petersen, Elina, Nikorowitsch, Julius, Müller, Jessica, Kölbel, Tilo, Reichenspurner, Hermann, Blankenberg, Stefan, Girdauskas, Evaldas“…Patients with moderate or severe AR were predominantly male at advanced age who had hypertension, coronary artery disease, atrial fibrillation, and renal dysfunction. Increasing AR severity correlated with higher absolute and indexed aortic root diameters (e.g., end-diastolic sinus of Valsalva for no-mild-moderate-severe AR in mm ± standard deviation: 34.06 ± 3.81; 35.65 ± 4.13; 36.13 ± 4.74; 39.67 ± 4.61; p < 0.001). …”
Publicado 2021
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98547por Arabi, Yaseen M, Hajeer, Ali H., Balkhy, Hanan, Al Johani, Sameera, Sadat, Musharaf, Al-Dawood, Abdulaziz, Abu Taleb, Alanoud, Jose, Jesna, Al Qasim, Eman, Al Ajlan, Abdulaziz“…Among the study cohort, 38 patients (95%) received invasive ventilation, 35 (88%) vasopressors, 21 (53%) renal replacement therapy and 17 (43%) corticosteroids. …”
Publicado 2021
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98548por Dimitrova, Dimana, Nademi, Zohreh, Maccari, Maria Elena, Ehl, Stephan, Uzel, Gulbu, Tomoda, Takahiro, Okano, Tsubasa, Imai, Kohsuke, Carpenter, Benjamin, Ip, Winnie, Rao, Kanchan, Worth, Austen J. J., Laberko, Alexandra, Mukhina, Anna, Néven, Bénédicte, Moshous, Despina, Speckmann, Carsten, Warnatz, Klaus, Wehr, Claudia, Abolhassani, Hassan, Aghamohammadi, Asghar, Bleesing, Jacob J., Dara, Jasmeen, Dvorak, Christopher C., Ghosh, Sujal, Kang, Hyoung Jin, Markelj, Gašper, Modi, Arunkumar, Bayer, Diana K., Notarangelo, Luigi D., Schulz, Ansgar, Garcia-Prat, Marina, Soler-Palacín, Pere, Karakükcü, Musa, Yilmaz, Ebru, Gambineri, Eleonora, Menconi, Mariacristina, Masmas, Tania N., Holm, Mette, Bonfim, Carmem, Prando, Carolina, Hughes, Stephen, Jolles, Stephen, Morris, Emma C., Kapoor, Neena, Koltan, Sylwia, Paneesha, Shankara, Steward, Colin, Wynn, Robert, Duffner, Ulrich, Gennery, Andrew R., Lankester, Arjan C., Slatter, Mary, Kanakry, Jennifer A.“…Phenotype reversal occurred in 96% of evaluable patients, of whom 17% had mixed chimerism. Vulnerability to renal complications continued post-HCT, adding new insights into potential nonimmunologic roles of phosphoinositide 3-kinase not correctable through HCT. …”
Publicado 2022
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98549por Harb, Serge C, Wang, Tom Kai Ming, Nemer, David, Wu, Yuping, Cho, Leslie, Menon, Venu, Wazni, Osama, Cremer, Paul C, Jaber, Wael“…In multivariable analysis, CHA(2)DS(2)-VASc score, presence of AF and anticoagulation use, along with end-stage renal failure and smoking were all independently associated with mortality with HRs (95% CIs) of 1.23 (1.21 to 1.25), 1.18 (1.10 to 1.27) and 1.50 (1.40 to 1.60), respectively. …”
Publicado 2021
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98550“…Additionally, robot-assisted partial nephrectomy (RAPN) has been proposed as a promising operative treatment for renal carcinoma because it enables early recovery and ambulation. …”
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98551“…Hematological, hepatic, and renal parameters were assessed in all subjects, while the activity of NK and NKT (natural killer T) cells was assessed in six randomly chosen subjects in each group by the degranulation assay. …”
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98552por Espi, Maxime, Charmetant, Xavier, Barba, Thomas, Mathieu, Cyrille, Pelletier, Caroline, Koppe, Laetitia, Chalencon, Elodie, Kalbacher, Emilie, Mathias, Virginie, Ovize, Anne, Cart-Tanneur, Emmanuelle, Bouz, Christine, Pellegrina, Laurence, Morelon, Emmanuel, Juillard, Laurent, Fouque, Denis, Couchoud, Cécile, Thaunat, Olivier“…To study this we used the French Renal Epidemiology and Information Network (REIN) Registry to compare the incidence and severity of 1474 cases of COVID-19 diagnosed in patients receiving MHD after none, one or two doses of vaccine. …”
Publicado 2022
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98553por Struck, Julian P., Schnoor, Maike, Schulze, Andrea, Hupe, Marie C., Ozimek, Tomasz, Oppolzer, Immanuel A., Schnabel, Marco J., Burger, Maximilian, Darr, Christopher, Gruenwald, Viktor, Hadaschik, Boris, Weinke, Maximilian, Kuebler, Hubert, Klockenbusch, Jonas C., Grabbert, Markus T., Gratzke, Christian, Kramer, Mario W., Katalinic, Alexander, Merseburger, Axel S.“…Treatment of patients with renal cell carcinoma (12/73, 16.4%) and urothelial carcinoma (7/32, 21.9%) was affected the most. …”
Publicado 2021
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98554“…In particular, five prognostic gene links for kidney renal papillary cell carcinoma tended to condense around cancer gene ESPL1, and the transcriptional synchrony between ESPL1 and PTTG1 tended to be elevated in patients of adverse prognosis. …”
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98555“…METHODS: We retrospectively analyzed the CT images of 65 pediatric patients with NWTs from March 2008 to July 2020, mainly including clear cell sarcoma of the kidney (CCSK), malignant rhabdomyoma tumor of the kidney (MRTK) and renal cell carcinoma (RCC). Available pretreatment contrast-enhanced abdominal CT examinations were reviewed. …”
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98556“…Cardiovascular, liver and renal function were normal before nephrectomy. Until now, all donors are alive and maintain overall good health. …”
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98557“…RESULTS: A novel prognostic nomogram for 3-year mortality was constructed with the seven independent prognostic factors, including age, congestive heart failure, white blood cell, creatinine, SpO(2), anion gap, and continuous renal replacement treatment derived from the multivariable logistic regression. …”
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98558por Martinez Chanza, Nieves, Soukane, Louisa, Barthelemy, Philippe, Carnot, Aurélien, Gil, Thierry, Casert, Vinciane, Vanhaudenarde, Vincent, Sautois, Brieuc, Staudacher, Lionel, Van den Brande, Jan, Culine, Stephane, Seront, Emmanuel, Gizzi, Marco, Albisinni, Simone, Tricard, Thibault, Fantoni, Jean Christophe, Paesmans, Marianne, Caparica, Rafael, Roumeguere, Thierry, Awada, Ahmad“…Unfortunately, many patients are not candidates to receive cisplatin due to renal impairment. Additionally, no predictive biomarkers for pathological complete response (pCR) are currently validated in clinical practice. …”
Publicado 2021
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98559por Bogossian, Harilaos, Panteloglou, Dimitrios, Karosiene, Zana, Macher-Heidrich, Susanne, Adomeit, Heinz Jürgen, Lemke, Bernd, Israel, Carsten W.“…The presence of diabetes mellitus (23% of the collective) did not influence the perioperative mortality, whereas renal failure requiring dialysis showed a significantly increased mortality (p < 0.001 compared to patients with creatinine ≤ 1.5 mg/dl and p = 0.002 for patients with creatinine > 1.5 mg/dl not requiring dialysis). …”
Publicado 2021
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98560“…Compared to HIV- patients, HIV+ were more likely to be identified as Black, with higher mean Elixhauser Comorbidity scores and significant associations with conditions such as hypertension, pulmonary disease, complicated diabetes, liver disease, renal failure and depression (Table 1). These co-morbidities have been correlated with higher risk of hospitalization for people living with HIV (PWH). …”
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