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  1. 98981
    por Mansour, Michael
    Publicado 2022
    “…Primary study endpoints were antimicrobial usage and composite safety comprising readmission, death, intubation, septic shock, renal failure, and pneumonia complications such as empyema and abscess up to day 30. …”
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    793. Procalcitonin-guided Antibiotic Stewardship Oversight Reduces Antibiotic Use and Adverse Outcomes for Patients Admitted with Pneumonia, Results from a Real-world Randomized Controlled Trial in US Hospitals
  2. 98982
    “…High rate of treatment failure was found among patients with chronic kidney diseases for which renally adjusted doses has been used((1)). In our institution, higher than labeled adjusted dosing regimens (HLAD) has been used for the treatment of severe infections. …”
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    606. Efficacy and Safety of Ceftazidime-Avibactam Comparative Dosage Regimens in Patients with Kidney Injury: A Retrospective Cohort Study
  3. 98983
    “…Baseline AKI (44% vs 46%) and renal impairment (8% vs 0%) were not different between GEN and no-GEN, respectively. …”
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    1986. Multicenter evaluation of Staphylococcus aureus prosthetic valve infective endocarditis with and without gentamicin treatment: Is it time to revisit?
  4. 98984
    “…They received most commonly remdesivir and corticosteroids for COVID-19, with 22 (95.6%) needing intensive care unit admission and 19 (82.6%) needing continuous renal replacement therapy. CFIs were diagnosed at median 21 days (range, 3-161) after initial COVID-19 diagnosis. …”
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    262. COVID-19 associated fungal co-infections in Solid Organ Transplant Recipients: A single center case series
  5. 98985
    “…The disease enrichment analysis of DEGs in kidney tissues showed that they were mainly involved in immune and renal diseases, and in peripheral blood it was mainly enriched in cardiovascular system, bone marrow, and oral cavity. …”
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    Predicting diagnostic gene expression profiles associated with immune infiltration in patients with lupus nephritis
  6. 98986
    “…Mechanism studies underlying these differences, as well as the need for identification of biomarkers to predict the early onset renal lesion, are warranted.…”
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    Ethnic differences in 25-year risk of incident chronic kidney disease among people with type 2 diabetes in New Zealand
  7. 98987
    “…Sub-lethal FIP toxicity induced hypochromic anemia, leukopenia, hypoproteinemia, hypoalbuminemia, hypoglobulinemia, and hepato-renal failure (increased urea and creatinine concentrations, as well as ALT and AST enzymes). …”
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    Dietary supplementation with Moringa oleifera leaves extract reduces the impacts of sub-lethal fipronil in Nile tilapia, Oreochromis niloticus
  8. 98988
    “…DAL was calculated based on potential renal acid load (PRAL) and net endogenous acid production (NEAP) methods. …”
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    The association between dietary acid load and body composition in physical education students aged 18–25 years
  9. 98989
    “…THESE CHANGES ARE 1) NO REQUIRED DURATION OF SUBJECTIVE OR MEASURED FEVER; 2) REQUIREMENT OF C-REACTIVE PROTEIN ≥3.0 MG/DL TO INDICATE SYSTEMIC INFLAMMATION; 3) ADJUSTMENTS TO CRITERIA OF ORGAN SYSTEM INVOLVEMENT TO INCLUDE ADDITION OF SHOCK AS A SEPARATE CATEGORY AND ELIMINATION OF RESPIRATORY, NEUROLOGIC, AND RENAL CRITERIA; AND 4) NEW REQUIREMENTS ON TIMING OF POSITIVE SARS-COV-2 LABORATORY TESTING RELATIVE TO THE MIS-C ILLNESS. …”
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    Council of State and Territorial Epidemiologists/CDC Surveillance Case Definition for Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 Infection — United States
  10. 98990
    “…RESULTS: Among 246 adult patients with EBV-HLH, the deceased were older (p < 0.05), with fewer blood cells (p < 0.05), poorer renal function (p < 0.01), higher levels of procalcitonin (PCT) (p < 0.01), as well as soluble interleukin-2 receptor (sCD25) (p < 0.01). …”
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    Improved hemophagocytic lymphohistiocytosis index predicts prognosis of adult Epstein-Barr virus-associated HLH patients
  11. 98991
    “…Common poorly justified exclusions included pregnancy related, age, and comorbidities (infectious/immunosuppression, hepatic, renal, and human immunodeficiency virus/acquired immunodeficiency syndrome). …”
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    Impact of differences in acute respiratory distress syndrome randomised controlled trial inclusion and exclusion criteria: systematic review and meta-analysis
  12. 98992
    “…Compared to patients without HF, HF patients were older (75.3 ± 9.9 vs. 73.8 ± 9.6 years; p = 0.01), had more diabetes (36.5% vs. 24.3%; p < 0.01), coronary artery disease (28.2% vs. 12.9%; p < 0.01), renal insufficiency (31.7% vs. 22.6%; p = 0.01), higher CHA(2)DS(2)-VASc (4.5 ± 1.6 vs. 3.2 ± 1.4; p < 0.01) and HAS-BLED (1.8 ± 1.1 vs. 1.5 ± 1.0; p < 0.01). …”
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    Impact of heart failure on the clinical profile and outcomes in patients with atrial fibrillation treated with rivaroxaban. Data from the EMIR study
  13. 98993
    “…As for the phenotype of the syndrome, our study identified the presence of some clinical features which were previously unrelated or poorly related to NS. For example, renal and central nervous system abnormalities were found at a higher rate compared to the current literature. …”
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    New insights on Noonan syndrome’s clinical phenotype: a single center retrospective study
  14. 98994
    “…These findings suggest differences in renal inflammation across ethnic groups.…”
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    Ethnic differences in urinary monocyte chemoattractant protein-1 and heparanase-1 levels in individuals with type 2 diabetes: the HELIUS study
  15. 98995
    “…BACKGROUND: Immunoglobulin A nephropathy (IgAN), a globally common primary chronic glomerulopathy, is one of the leading causes of end-stage renal disease. However, the underlying mechanisms of IgAN have yet to be demonstrated. …”
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    LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy
  16. 98996
    “…Mendelian randomization analysis confirms numerous phenotypes across a breadth of organ systems, including conditions of the circulatory (heart failure, ischemic heart disease, atrial fibrillation), genitourinary (chronic renal failure), respiratory (respiratory failure, asthma), musculoskeletal and dermatologic systems that are deeply interconnected within and across the disease communities. …”
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    Genomics and phenomics of body mass index reveals a complex disease network
  17. 98997
    “…RESULTS: The GULP study included 127 patients with SLE; 73 (57.5%) tapered and maintained PDN <5 mg/day, and 17 (13.4%) discontinued PDN within a 2-year follow-up. Renal involvement (HR: 0.41; p=0.009) and lower C3 serum levels (HR: 1.04; p=0.025) predicted a lack of PDN tapering below 5 mg/day. …”
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    Glucocorticoid tapering and associated outcome in patients with newly diagnosed systemic lupus erythematosus: the real-world GULP prospective observational study
  18. 98998
    “…Among 670 patients, major adverse outcomes were present in 169 patients (25.2%), 67 patients (10.0%) required renal replacement therapy (RRT), and 80 (11.9%) developed severe postoperative AKI. …”
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    Risk factors for severe acute kidney injury post complication after total arch replacement combined with frozen elephant trunk, in acute type A aortic dissection
  19. 98999
    “…For example, methylation of PRGs in lower grade glioma (LGG), uveal melanoma (UVM) and kidney renal clear cell carcinoma (KIRC) were predictive of improved survival as upregulation of PRGs was risky in these cancers. …”
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    Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspective
  20. 99000
    “…After a median follow-up time of 29.7 months, patients with higher burden of skin, endocrine and musculoskeletal irAEs (the latter two’s effect was confirmed at multivariable analysis) had longer overall survival (OS), as opposed to gastrointestinal, pneumonitis, neurological, liver, renal and other irAEs, which showed an harmful effect. …”
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    Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer
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