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99261“…On propagation in cynomolgus kidney cultures the modified viruses reached titers of approximately 10(7) TCD(50) per ml., as measured by cytopathogenic activity on renal epithelial cells in vitro, yet produced no perceptible pathologic changes in the muscles, kidneys, testes, ovaries, heart, pancreas, adrenals, liver, or spleen of cynomolgus monkeys inoculated intramuscularly. …”
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99262por Zappitelli, Michael, Washburn, Kimberly K, Arikan, Ayse A, Loftis, Laura, Ma, Qing, Devarajan, Prasad, Parikh, Chirag R, Goldstein, Stuart L“…Patients with end-stage renal disease or who had just undergone kidney transplantation were excluded. …”
Publicado 2007
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99263por van der Woude, Fokke J, Heinemann, Lothar AJ, Graf, Helmut, Lewis, Michael, Moehner, Sabine, Assmann, Anita, Kühl-Habich, Doerthe“…METHODS: We performed a population-based case-control study with incident cases of end-stage renal disease (ESRD) under the age of 50 years and four age and sex-matched neighborhood controls in 170 dialysis centers (153 in Germany, and 17 in Austria) from January 1, 2001 to December 31, 2004. …”
Publicado 2007
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99264por Culine, S, Theodore, C, De Santis, M, Bui, B, Demkow, T, Lorenz, J, Rolland, F, Delgado, F-M, Longerey, B, James, N“…Moreover, and of importance in this particular study population, no grade 3–4 renal function impairment was observed. Vinflunine is an active agent for the treatment of platinum-pretreated bladder cancer, and these results warrant further investigation in phase III trials, either as monotherapy or in combination with other agents as treatment of advanced/metastatic TCC of the bladder.…”
Publicado 2006
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99265por Wardley, A, Davidson, N, Barrett-Lee, P, Hong, A, Mansi, J, Dodwell, D, Murphy, R, Mason, T, Cameron, D“…There was no difference between hospital and community administration in renal or other toxicity, with zoledronic acid being well tolerated in both treatment settings. …”
Publicado 2005
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99266“…Analogues substituted in the 3′ position with I (DF 129), CH (3)(DF 203), or CI (DF 229) possess an extended profile of antitumour activity with remarkable selective activity in cell lines derived from solid tumours associated with poor prognosis, e.g. breast, ovarian, renal and colon. Growth inhibition occurs via unknown, possibly novel mechanism(s) of action. …”
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99267por Hussain, S A, Stocken, D D, Peake, D R, Glaholm, J G, Zarkar, A, Wallace, D M A, James, N D“…Organ preservation using multimodality therapy is feasible and safe, even in patients with poor renal reserve, and does not compromise salvage therapies. …”
Publicado 2004
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99268por Morant, R, Bernhard, J, Dietrich, D, Gillessen, S, Bonomo, M, Borner, M, Bauer, J, Cerny, T, Rochlitz, C, Wernli, M, Gschwend, A, Hanselmann, S, Hering, F, Schmid, H-P“…The inclusion criteria were PSA serum levels >3 × upper limit of normal, a WHO performance status 0–2, age <85 years and adequate bone marrow, liver and renal function. In patients with grade 2 or higher haematological toxicity on day 1 of the treatment cycle, therapy was first delayed, and then continued at a lower dose. …”
Publicado 2004
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99269por Yu, Hongjie, Gao, Zhancheng, Feng, Zijian, Shu, Yuelong, Xiang, Nijuan, Zhou, Lei, Huai, Yang, Feng, Luzhao, Peng, Zhibin, Li, Zhongjie, Xu, Cuiling, Li, Junhua, Hu, Chengping, Li, Qun, Xu, Xiaoling, Liu, Xuecheng, Liu, Zigui, Xu, Longshan, Chen, Yusheng, Luo, Huiming, Wei, Liping, Zhang, Xianfeng, Xin, Jianbao, Guo, Junqiao, Wang, Qiuyue, Yuan, Zhengan, Zhou, Longnv, Zhang, Kunzhao, Zhang, Wei, Yang, Jinye, Zhong, Xiaoning, Xia, Shichang, Li, Lanjuan, Cheng, Jinquan, Ma, Erdang, He, Pingping, Lee, Shui Shan, Wang, Yu, Uyeki, Timothy M., Yang, Weizhong“…Clinical complications included acute respiratory distress syndrome (ARDS, 81%), cardiac failure (50%), elevated aminotransaminases (43%), and renal dysfunction (17%). Fatal cases had a lower median nadir platelet count (64.5×10(9) cells/L vs 93.0×10(9) cells/L, p = 0.02), higher median peak lactic dehydrogenase (LDH) level (1982.5 U/L vs 1230.0 U/L, p = 0.001), higher percentage of ARDS (94% [n = 16] vs 56% [n = 5], p = 0.034) and more frequent cardiac failure (71% [n = 12] vs 11% [n = 1], p = 0.011) than nonfatal cases. …”
Publicado 2008
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99270por Roizen, Mariana, Rodríguez, Susana, Bauer, Gabriela, Medin, Gabriela, Bevilacqua, Silvina, Varni, James W, Dussel, Veronica“…Chronically ill children were: (1) attending outpatient clinics and (2) had one of the following diagnoses: stem cell transplant, chronic obstructive pulmonary disease, HIV/AIDS, cancer, end stage renal disease, complex congenital cardiopathy. Patients and adult proxies completed the PedsQL™ 4.0 and an overall health status assessment. …”
Publicado 2008
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99271por Valle, J W, Wasan, H, Johnson, P, Jones, E, Dixon, L, Swindell, R, Baka, S, Maraveyas, A, Corrie, P, Falk, S, Gollins, S, Lofts, F, Evans, L, Meyer, T, Anthoney, A, Iveson, T, Highley, M, Osborne, R, Bridgewater, J“…METHODS: Patients, aged ⩾18 years, with pathologically confirmed ABC, Karnofsky performance (KP) ⩾60, and adequate haematological, hepatic and renal function were randomised to G 1000 mg m(−2) on D1, 8, 15 q28d (Arm A) or C 25 mg m(−2) followed by G 1000 mg m(−2) D1, 8 q21d (Arm B) for up to 6 months or disease progression. …”
Publicado 2009
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99272por Oudemans-van Straaten, Heleen M, van Schilfgaarde, Muriel, Molenaar, Pascal J, Wester, Jos PJ, Leyte, Anja“…INTRODUCTION: Renal insufficiency increases the half-life of low molecular weight heparins (LMWHs). …”
Publicado 2009
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99273“…This practice is of equal importance in reducing cyclosporine-related renal toxicity, a rather irreversible process.…”
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99274por Parkash, Om, Almas, Aysha, Jafri, SM Wasim, Hamid, Saeed, Akhtar, Jaweed, Alishah, Hasnain“…There was a significant difference for the complications like Bleeding (P value < 0.001), Acute Renal failure (ARF) (P value 0.002), Acalculus cholecystitis (P value 0.04) and encephalopathy (P value 0.02) in mild/moderate and Severe hepatitis groups respectively. …”
Publicado 2010
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99275por Schroeder, Rogier P. J., Müller, Cristina, Reneman, Suzanne, Melis, Marleen L., Breeman, Wout A. P., de Blois, Erik, Bangma, Chris H., Krenning, Eric P., van Weerden, Wytske M., de Jong, Marion“…CONCLUSION: In the present study the BN antagonist Demobesin-1 was the best performing analogue showing superior in vivo stability, highest tumour uptake and retention while pancreatic and renal clearance were rapid. PESIN and AMBA were the best GRP agonists with sufficient in vivo stabilities as well as high tumour uptake and retention. …”
Publicado 2010
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99276por Frei, Christopher R, Mortensen, Eric M, Copeland, Laurel A, Attridge, Russell T, Pugh, Mary Jo V, Restrepo, Marcos I, Anzueto, Antonio, Nakashima, Brandy, Fine, Michael J“…RESULTS: Of 40,878 patients, African-Americans (n = 4,936) were less likely to be married and more likely to have a substance use disorder, neoplastic disease, renal disease, or diabetes compared to Caucasians. …”
Publicado 2010
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99277“…We found strong evidence to classify the following interventions as cost saving or very cost-effective: (I) Cost saving— 1) ACE inhibitor (ACEI) therapy for intensive hypertension control compared with standard hypertension control; 2) ACEI or angiotensin receptor blocker (ARB) therapy to prevent end-stage renal disease (ESRD) compared with no ACEI or ARB treatment; 3) early irbesartan therapy (at the microalbuminuria stage) to prevent ESRD compared with later treatment (at the macroalbuminuria stage); 4) comprehensive foot care to prevent ulcers compared with usual care; 5) multi-component interventions for diabetic risk factor control and early detection of complications compared with conventional insulin therapy for persons with type 1 diabetes; and 6) multi-component interventions for diabetic risk factor control and early detection of complications compared with standard glycemic control for persons with type 2 diabetes. …”
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99278por Javle, Milind M, Shroff, Rachna T, Xiong, Henry, Varadhachary, Gauri A, Fogelman, David, Reddy, Shrikanth A, Davis, Darren, Zhang, Yujian, Wolff, Robert A, Abbruzzese, James L“…METHODS: Two studies prospectively enrolled adult patients with advanced pancreatic cancer, Eastern Cooperative Oncology Group performance status 0-1, adequate hematologic, hepatic and renal parameters and measurable disease. In Study A, temsirolimus was administered intravenously at 25 mg weekly. …”
Publicado 2010
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99279por Mathur, Rajkumar, Joshi, Nitin, Aggarwal, Gaurav, Raikwar, Ramsharan, Shrivastava, Vaibhav, Mathur, Poonam, Raikwar, Poonam, Joshi, Rupali“…A thorough urological examination included a dye study using methylene blue, Renal function tests, X-ray KUB and intravenous urography (IVU). …”
Publicado 2010
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99280“…Increased IP-10, MCP-1, ICAM-1 and VCAM-1 concentrations of preeclamptic patients showed significant correlations with blood pressure values, renal and liver function parameters, as well as with CRP, malondialdehyde, von Willebrand factor antigen and fibronectin levels. …”
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