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100421“…To further evaluate thrombi, CT scan of the abdomen and pelvis was performed, revealing bilaterally enlarged and hypoenhancing adrenal glands likely related to ischemia or infarction along with left renal vein thrombosis. Laboratory work-up returned positive for anti-cardiolipin IgM and IgG antibodies. …”
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100422“…Among other tests that residents would perform are: TSH (87%), renal ultrasound with arterial Doppler (75%), CBC (34%), and almost one third of residents (27%) would order transthoracic echocardiogram. …”
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100423“…Additionally, patients with CDC73 related disorders are more prone to developing ossifying fibroma(s) of the jaw, uterine tumors, and various renal lesions. In summary, this case highlights the diagnostic and therapeutic challenges in a patient with persistent primary hyperparathyroidism after a failed second surgery. …”
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100424“…Review of the labs showed that renal function, complete blood count and fasting plasma glucose were within the normal range. …”
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100425por Champagne, Kareen, Mooradian, Arshag D, Gupta, Nidhi, Haas, Michael J, Gandhi, Gunjan Y, Jurado-Flores, Marilu M“…Introduction: Acute elevation of serum phosphorous occurs for various reasons, including cellular injury (hemolysis, rhabdomyolysis, tumor lysis syndrome), decreased excretion (acute renal injury), or increased absorption/intake. Case Description: A 20-year-old woman presented as a pedestrian struck by a car after a motor vehicle accident. …”
Publicado 2023
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100426por Hershkop, Eliyakim“…Severe hypercalcemia can lead to renal failure, arrhythmias, and coma. A rare EKG finding is ST elevation mimicking an acute ST Elevation Myocardial Infarction (STEMI). …”
Publicado 2023
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100427“…On her first presentation, severe hypercalcemia (13.8 mg/dL), acute-on-chronic renal disease, a normal TSH, an appropriately low PTH, elevated PTHrP, a low 25-hydroxy vitamin D, and a normal 1,25 dihydroxy-vitamin D were noted. …”
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100428“…Work up revealed a glucose of 34 mg/dl (70 - 109 mg/dl), insulin of 40.1 (2.6 - 24.9 uIU/mL), C-peptide of 3.8 (1.1 - 4.4 ng/mL), potassium of 3.2 (3.5 - 4.8 meq/l), negative sulfonylurea screen, normal renal function, and a mild leukocytosis of 12.6 (4.0 - 11.0 x 10*3/µL). …”
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100429“…Conclusion: Hypercalcemia of malignancy is common in many different carcinomas with squamous cell cancer, renal cell cancer, breast cancer and multiple myeloma being commonly associated with this phenomenon. …”
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100430por Bosques-Lorenzo, Jaymilitte, Rivera, Patricia, Colon-Castellano, Janet, Otero-Dominguez, Yomayra“…Laboratories showed an elevated TSH (296.8 uIU/mL), with low total T3 and free T4 (45.03 ng/dL and 0.228 ng/dL respectively) with a myxedema score of 45. Altered renal parameters as per BUN and creatinine levels (83.4 mg/dL and 5.75 mg/dL) without electrolytes disturbances and elevated CPK (1250 U/L). …”
Publicado 2023
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100431por Parksook, Wasita W, Heydarpour, Mahyar, Pojoga, Luminita, Gaye, Amadou, Gibbons, Gary H, Williams, Gordon H, Williams, Jonathan S“…There were no differences between plasma renin activity, serum and urinary cortisol levels, and renal plasma flows between genotypes. Conclusions: There was an association between the ARMC5 rs4889660 variant and SSBP in Caucasians. …”
Publicado 2023
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100432“…Abdominal ultrasound revealed cholelithiasis without evidence of acute cholecystitis and unremarkable renal findings. CT abdomen pelvis with contrast showed thickening with surrounding stranding of right adrenal gland suggesting acute adrenal infarction and multiple pancreatic cysts. 8 am cortisol was 4.9 mcg/dl (4.1-16.6 mcg/dl) and ACTH was 23 pg/ml (7.2-63.3 pg/ml). …”
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100433“…Simplified acute physiology score (SAPSII), red blood cell distribution width (RDW), beta-blocker, race, respiratory rate, urine output, coronary artery bypass grafting (CABG), Charlson comorbidity index, renal replacement therapies (RRT), antiarrhythmic, age, and anticoagulation were predictors finally included in the prediction model. …”
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100434por Le, Dustin, Chen, Jingsha, Shlipak, Michael G., Ix, Joachim H., Sarnak, Mark J., Gutierrez, Orlando M., Schelling, Jeffrey R., Bonventre, Joseph V., Sabbisetti, Venkata S., Schrauben, Sarah J., Coca, Steven G., Kimmel, Paul L., Vasan, Ramachandran S., Grams, Morgan E., Parikh, Chirag, Coresh, Josef, Rebholz, Casey M.“…OUTCOME: Incident CKD after 15 years of follow-up defined as ≥40% estimated glomerular filtration rate decline to <60 mL/min/1.73 m(2) or dialysis dependence through United States Renal Data System linkage. ANALYTICAL APPROACH: Logistic regression and C statistics. …”
Publicado 2023
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100435por Li, Song, Chen, Dianze, Guo, Huiqin, Liu, Dandan, Yang, Chunmei, Zhang, Ruliang, Wang, Tianxiang, Zhang, Fan, Bai, Xing, Yang, Yanan, Sun, Nana, Zhang, Wei, Zhang, Li, Zhao, Gui, Peng, Liang, Tu, Xiaoping, Tian, Wenzhi“…A strong synergistic effect between IMM01 (SIRPα-Fc fusion protein) and IMM40H was recorded in Burkitt’s lymphoma Raji and renal carcinoma cell A498 tumor models. In cynomolgus monkeys, the highest non-severely toxic dose (HNSTD) for repeat-dose toxicity was up to 30 mg/kg, while the maximum tolerated dose (MTD) for single-dose toxicity was up to 100 mg/kg, confirming that IMM40H had a good safety and tolerability profile. …”
Publicado 2023
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100436por Fitzpatrick, Donal, Lannon, Rosaleen, Laird, Eamon, Ward, Mary, Hoey, Leane, Hughes, Catherine F., Strain, J. J., Cunningham, Conal, McNulty, Helene, Molloy, Anne M., McCarroll, Kevin“…Participants with an estimated glomerular filtration rate (eGFR) < 30 ml/min and serum calcium > 2.5 mmol/l were excluded to avoid hyperparathyroidism due to chronic renal disease and primary hyperparathyroidism. Hyperparathyroidism was defined as a parathyroid hormone (PTH) > 65 pg/ml. …”
Publicado 2023
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100437por Mahato, Abhishek, Jain, Anurag, Prakash, V.S, Nair, Rajesh, Joshi, Richa, Paliwal, Dharmesh, Tiwari, Awadhesh, Khandpur, Sukhanshi, Singh, Harkirat“…Empagliflozin is a novel sodium glucose type 2 inhibitor that prevents tubular reabsorption of glucose and increases renal glycosuria resulting in decreased blood sugar. …”
Publicado 2023
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100438por Fragasso, Tiziana, Raggi, Valeria, Passaro, Davide, Tardella, Luca, Lasinio, Giovanna Jona, Ricci, Zaccaria“…CONCLUSIONS: We validated a ML model to detect AKI occurring after 48 h in a retrospective observational study that could help clinicians in individuating patients at risk of AKI, in which a preventive strategy can be determinant to improve the occurrence of renal dysfunction. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s44158-023-00125-3.…”
Publicado 2023
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100439por Hashmi, Syeda Akefah, Khowaja, Raheela, Ali, Maria, Mangi, Ali R, Khowaja, Aamir, Riaz, Gohar, Hashmi, Syed Muhammad Mahad, Haider, Ali Raza, Hussain, Syed Danish Afaque, Agha, Sidrah“…Patients were monitored throughout their ICU stay, and any adverse events or complications, such as re-intubation, bleeding necessitating transfusion, requirement for renal replacement therapy, arrhythmias, re-infarction, and mortality, were recorded. …”
Publicado 2023
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100440“…Additionally, the relationship was also robust in several populations, such as patients were younger than 60 years, or had not a history of congestive heart failure, or had a history of sepsis, or had not received renal replacement therapy, or had a duration of mechanical ventilation for more than 7 days. …”
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