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100581“…Prior to presentation, his baseline calcium was normal and PTH had ranged 150-180 pg/ml with similar renal function as on admission. A parathyroid ultrasound and sestamibi scan were negative for a parathyroid adenoma. …”
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100582por Delaney, Angela, Volochayev, Rita, Meader, Brooke, Lee, Janice, Almpani, Nadine, Noukelak, Germaine, Brooks, Brian, Henkind, Jennifer, Chalmers, Laura, Law, Jennifer, Williamson, Kathleen, Jacobsen, Christina, Buitrago, Tatiana Pineda, Silva, Orlando Perez, Chie-Hee, Cho, Kaindl, Angela, Anita, Rauch, steindl, Katharina, Garcia-Ortiz, Jose, Bart, Loeys, Russell, Bianca, Prasad, Rameshwar, Mondal, Uttam, Reigstad, Hallvard Martin, Clements, Scott, Salnikov, Kathryn, DiOrio, Nicole, Balasubramanian, Ravikumar, Dwyer, Andrew, Seminara, Stephanie, Crowley, William, Plummer, Lacey, Hall, Janet, Graham, John, Lin, Angela, Shaw, Natalie“…Subjects with arhinia demonstrated some, but not all, non-reproductive phenotypes characteristic of Kallmann syndrome (KS) and/or CHARGE syndrome including dental agenesis (56%) and congenital mirror movements (CMMs; 50%); none had renal agenesis, severe congenital heart defects, or deafness. …”
Publicado 2019
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100583por Motazedi, Banafsheh“…Patient’s condition quickly deteriorated due to severe lactic acidosis thus requiring two additional pressor support with infusion of Norepinephrine and Vasopressin as well as addition of Hydrocortisone and oral Midodrine. His renal function worsened, and he became oliguric. …”
Publicado 2019
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100584por Hannan, Fadil, Olesen, Mie, Hough, Tertius, Stewart, Michelle, Wells, Sara, Thakker, Rajesh“…Although loss-of-function point mutations of the GNA11 gene, which encodes Gα(11), have been shown to increase plasma calcium concentrations and cause familial hypocalciuric hypercalcemia type 2 (FHH2), the overall contribution of Gα(11) to the parathyroid, bone and renal regulation of calcium homeostasis remains to be established. …”
Publicado 2019
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100585“…Their mechanism of action involves increasing urinary glucose excretion by preventing glucose reabsorption in the proximal renal tubules, yet they can also promote ketogenesis under certain circumstances. …”
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100586por De Sousa, Sunita M.C., Toubia, John, Feng, Jingua, Wang, Paul, Hardy, Tristan S.E., Babic, Milena, Geoghegan, Joel, Hall, Rachel, Scott, Grist, Rawlings, Lesley, Schreiber, Andreas, Luxford, Catherine, Clifton-Bligh, Roderick, Poplawski, Nicola, Scott, Hamish, Torpy, David“…Introduction: Germline mutations in the succinate dehydrogenase genes (SDHA/B/C/D, SDHAF2 - collectively, SDHx) have been implicated in paraganglioma (PGL), renal cell carcinoma (RCC), gastrointestinal stromal tumor (GIST) and pituitary adenoma (PA). …”
Publicado 2019
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100587por Ramalho, Sergio H. R., Santos, Mario, Claggett, Brian, Matsushita, Kunihiro, Kitzman, Dalane W., Loehr, Laura, Solomon, Scott D., Skali, Hicham, Shah, Amil M.“…Moderate to severe dyspnea was also associated with obstructive (OR, 1.59; 95% CI, 1.28-1.99; P < .001) and restrictive (OR, 2.56; 95% CI, 1.99-3.27; P < .001) findings on spirometry, renal impairment (OR, 1.32; 95% CI, 1.08-1.61; P = .01), anemia (OR, 1.72; 95% CI, 1.39-2.12; P < .001), lower (OR, 2.77; 95% CI, 2.18-3.51; P < .001) and upper (OR, 1.82; 95% CI, 1.49-2.23; P < .001) extremity weakness, depression (OR, 3.01; 95% CI, 2.24-4.25; P < .001), and obesity (OR, 2.35; 95% CI, 1.95-2.83; P < .001). …”
Publicado 2019
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100588por Raman, Jaishree, Allen, Elizabeth, Workman, Lesley, Mabuza, Aaron, Swanepoel, Hendrik, Malatje, Gillian, Frean, John, Wiesner, Lubbe, Barnes, Karen I.“…Day 7 lumefantrine concentrations and the number and nature of adverse events were similar between study arms; only one serious adverse event occurred (renal impairment in the no primaquine arm). The artemether–lumefantrine PCR-corrected adequate clinical and parasitological response rate was 100%, with only one re-infection found among the 128 patients who completed 42-day follow-up. …”
Publicado 2019
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100589por Massierer, Daniela, Sapir-Pichhadze, Ruth, Bouchard, Vanessa, Dasgupta, Kaberi, Fernandez, Nicolas, da Costa, Deborah, Ahmed, Sara, Fortin, Marie-Chantal, Langevin, Rosalie, Mayo, Nancy, Janaudis-Ferreira, Tania“…BACKGROUND: Although it is well known that compared with dialysis, kidney transplantation improves the quality of life (QoL) of patients with end-stage renal disease, posttransplant recovery of physical health and other aspects of QoL remain well below age- and sex-matched norms. …”
Publicado 2019
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100590por Feinstein, Matthew J., Nance, Robin M., Delaney, J. A. Chris, Heckbert, Susan R., Budoff, Matthew J., Drozd, Daniel R., Burkholder, Greer A., Willig, James H., Mugavero, Michael J., Mathews, William C., Moore, Richard D., Eron, Joseph J., Napravnik, Sonia, Hunt, Peter W., Geng, Elvin, Hsue, Priscilla, Peter, Inga, Lober, William B., Crothers, Kristina, Grunfeld, Carl, Saag, Michael S., Kitahata, Mari M., Lloyd-Jones, Donald M., Crane, Heidi M.“…Significant mortality predictors after T1MI were higher HIV viral load, renal dysfunction, and older age. Significant predictors of mortality after T2MI were low body-mass index (BMI) and detectable HIV viral load. …”
Publicado 2019
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100591por Heckmann, Markus B., Totakhel, Belal, Finke, Daniel, Anker, Markus S., Müller‐Tidow, Carsten, Haberkorn, Uwe, Katus, Hugo A., Lehmann, Lorenz H.“…Univariate logistic regression models were created for increased cardiac and skeletal muscle (18)F‐FDG uptake using cancer entity, sex, age, previous radiation, previous chemotherapy, diabetes, obesity, serum glucose levels, renal function, and thyroid function as parameters. …”
Publicado 2019
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100592por Tian, Dongli, Shi, Xiaoxiao, Zhao, Yumo, Peng, Xiaoyan, Zou, Linfeng, Xu, Lubin, Ma, Ying, Wen, Yubin, Faulhaber-Walter, Robert, Chen, Limeng“…A1AR, caspase-1, interleukin-18 (IL-18) expression were analyzed using Western blotting in wild-type and A1AR(−/-) mice. Human renal proximal tubular epithelial cells (PTC) were cultured with high glucose to observe the effect of A1AR agonist and antagonist on caspase-1/IL-18 and megalin injury. …”
Publicado 2019
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100593por Husain, S. Ali, King, Kristen L., Pastan, Stephen, Pazter, Rachel E., Cohen, David J., Radhakrishnan, Jai, Mohan, Sumit“…IMPORTANCE: In the United States, substantial disparities in access to kidney transplant exist for wait-listed candidates with end-stage renal disease. The implications of transplant centers’ willingness to accept kidney offers for access to transplant and mortality outcomes are unknown. …”
Publicado 2019
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100594por Lee, Yen-Chieh, Wang, Jiun-Ling, Dong, Yaa-Hui, Chen, Hsi-Chieh, Wu, Li-Chiu, Chang, Chia-Hsuin“…A Cox proportional hazard regression model, adjusted for age, sex, body mass index (BMI), smoking, alcohol consumption, education level, diabetes, renal function, systemic steroids, and history of hospitalization, was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for overall and individual sites of infection and infection-related mortality. …”
Publicado 2019
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100595“…BACKGROUND: Collagen type IV (COL4)-related nephropathy includes a variety of kidney diseases that occur with or without extra-renal manifestations caused by COL4A3-5 mutations. …”
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100596por Pedersini, Rebecca, Amoroso, Vito, Maffezzoni, Filippo, Gallo, Fabio, Turla, Antonella, Monteverdi, Sara, Ardine, Mara, Ravanelli, Marco, Vassalli, Lucia, Rodella, Filippo, Formenti, Anna Maria, Dalla Volta, Alberto, Simoncini, Edda Lucia, Giustina, Andrea, Maroldi, Roberto, Berruti, Alfredo“…Eligible patients in both groups had normal renal function, no metabolic diseases, and no previous or current treatment with antiosteoporotic drugs or glucocorticoids. …”
Publicado 2019
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100597por Yassin, Arsheena, Chin, Titania, Meleshkina, Daria, Ghanbar, Mohammad, Sassine, Joseph, Olivo Freites, Christian, Stavropoulos, Christine, Farkas, Andras“…Next, multivariable regression was undertaken to predict this desired dose with frequently calculated weight and renal function indices. Last, model validation in a test data set based on calculated ME, RMSE and their 95% CI took place, and then the best model was used to simulate TDDs at 24 h intervals. …”
Publicado 2019
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100598“…The co-administration of nephrotoxic medications and the direct effect of infection limit our ability to assess the relative impact of CDV on renal function. Our data underscores the need for safer treatment options for HCT patients with life-threatening infections with dsDNA viruses. …”
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100599por Vanessa. Garcia, Cristina, E. Teo, Greg Matthew, Morano, Jamie P, Casanas, Beata, Aslam, Sadaf, Montero, Jose, Zeitler, Kristen, Jariwala, Ripal, Cannella, Anthony“…Notable comorbidities included COPD (n = 83), cystic fibrosis (n = 41), lung transplant (n = 40), heart transplant (n = 12), pulmonary fibrosis (n = 12), and renal transplant (n = 7). A total of 145 individuals received HIV testing at the hospital facility, and of these 44 individuals were living with HIV. …”
Publicado 2019
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100600por Schranz, Jennifer, Das, Anita F, Alexander, Elizabeth, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Gelone, Steven P“…There was no apparent relationship between ECR and age, gender, renal status, SIRS, PORT, prior antibiotic use, baseline pathogens, typical/atypical pathogens, or mono/polymicrobial pathogens. …”
Publicado 2019
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