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  1. 100821
    “…The primary outcome is prediction of moderate to severe AKI (Stage 2/3), and secondary outcomes are prediction of any AKI (Stage 1/2/3) and requirement of renal replacement therapy (RRT). Predictions generate alerts allowing fast assessment and reduction of AKI risk, such as: “patient has 90% risk of developing AKI in the next 48 h” along with contextual information and suggested response such as “patient on aminoglycosides, suggest check level and review dose and indication”. …”
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    Machine learning model for early prediction of acute kidney injury (AKI) in pediatric critical care
  2. 100822
    “…There was a low incidence of comorbidities: arterial hypertension, 49% (29 studies); diabetes mellitus, 29.6% (29 studies); dyslipidemia, 20.5% (27 studies); chronic obstructive pulmonary disease, 8.5% (26 studies); coronary disease, 8.3% (26 studies); and chronic renal disease, 7.6% (28 studies). Medical treatment was selected as first-line treatment for 41.8% of cases. …”
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    Acute limb ischemia among patients with COVID-19 infection
  3. 100823
    “…The geometric mean apparent terminal half-life decreased from 33.5 h (5 mg) to 14.5 h (160 mg) remaining stable up to 360 mg. Renal excretion of BI 187004 was low (3–5%). Urinary tetrahydrocortisol/tetrahydrocortisone ratio decreased, indicating liver 11beta-HSD1 inhibition. …”
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    Safety, tolerability, pharmacokinetics and pharmacodynamics of single oral doses of BI 187004, an inhibitor of 11beta-hydroxysteroid dehydrogenase-1, in healthy male volunteers with overweight or obesity
  4. 100824
    “…BACKGROUND: End-Stage Kidney Disease, the most severe form of chronic kidney disease, is fatal if not treated by renal replacement therapy. Thus, patients with End-Stage Kidney Disease depend on hemodialysis as a lifesaving treatment for the remainder of their lives. …”
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    Health related quality of life (HRQOL) of patients with End Stage Kidney Disease (ESKD) on hemodialysis in Addis Ababa, Ethiopia: a cross-sectional study
  5. 100825
    “…Secondary endpoints are a neurological outcome, mortality, length of ICU and hospital stay, myocardial injury, vasopressor support, lung injury score, ventilator-free days, renal function, ICU-acquired weakness, delirium, oxidative stress parameters, and plasma vitamin C concentrations. …”
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    Early high-dose vitamin C in post-cardiac arrest syndrome (VITaCCA): study protocol for a randomized, double-blind, multi-center, placebo-controlled trial
  6. 100826
    “…While small animal PET imaging revealed unfavorable biliary excretion of most of the (18)F-labeled compounds, the NOTA bearing compounds [(18)F]AlF-FAPI-74 and -75 achieved good tumor-to-background ratios, as a result of their preferred renal excretion. These two compounds showed the highest tumor accumulation in PET imaging. …”
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    (18)F-labeled tracers targeting fibroblast activation protein
  7. 100827
    “…Clinical pharmacist interventions reduce medication-related errors, improve therapeutic outcomes such as blood pressure, glycemic control, lipid control, CD4 T lymphocytes, and renal functions, and improve humanistic outcomes such as patient knowledge, adherence, and health-related quality of life. …”
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    The impact of clinical pharmacist services on patient health outcomes in Pakistan: a systematic review
  8. 100828
    “…Based on the previously published potent GLP-1R-activating undecapeptide 1, short-chained GLP-1R ligands were developed to investigate whether kidney uptake can be reduced by means of direct (18)F-labeling (nuclide-based accelerated renal excretion) or the reduction of the overall ligand charge (ligand-based reduced kidney uptake). …”
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    Small peptide-based GLP-1R ligands: an approach to reduce the kidney uptake of radiolabeled GLP-1R-targeting agents?
  9. 100829
    por Hardin, Jill, Reps, Jenna M.
    Publicado 2021
    “…AUC of 0.631 with all-time lookback) and 0.012 for renal impairment (in MDCR AUC of 0.675 with 30-day lookback vs. …”
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    Evaluating the impact of covariate lookback times on performance of patient-level prediction models
  10. 100830
    “…Phenotype III (n = 1078; 28%) was strongly correlated with renal dysfunction and acidosis and had the highest mortality rate (22%). …”
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    Identification of distinct clinical phenotypes of acute respiratory distress syndrome with differential responses to treatment
  11. 100831
    “…Results were adjusted for unit characteristics (pre-pandemic size), individual patient-level demographic characteristics (age, sex, ethnicity, deprivation index, time-to-ICU admission), and recorded chronic comorbidities (obesity, diabetes, respiratory disease, liver disease, heart disease, hypertension, immunosuppression, neurological disease, renal disease). RESULTS: One hundred thirty-five thousand six hundred patient days were observed, with a mortality rate of 19.4 per 1000 patient days. …”
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    The association between mechanical ventilator compatible bed occupancy and mortality risk in intensive care patients with COVID-19: a national retrospective cohort study
  12. 100832
    “…There were no differences in the other renal outcomes between the two groups. CONCLUSIONS: Comprehensive care by an MDCT is feasible and could be implemented for severe AKI survivors. …”
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    Comprehensive versus standard care in post-severe acute kidney injury survivors, a randomized controlled trial
  13. 100833
    “…CONCLUSIONS: This study suggested that the BIS1 equation was the most applicable for estimating GFR in Chinese elderly patients with moderate to severe renal impairment.…”
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    Applicability of Creatinine-based equations for estimating glomerular filtration rate in elderly Chinese patients
  14. 100834
    “…In addition, while some rats in the Can group exhibited brain hemorrhaging and renal dysfunction at 16 weeks old, no symptoms were observed in the FHCO group. …”
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    Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats
  15. 100835
    “…The data were analyzed by a Cox regression with the time variable defined as the length between the age at the time of recruitment and that at the end of the study (the age of death or censoring), and risk factors including gender, age, body mass index (BMI), presence of diabetes, lipid levels, renal function, serum uric acid levels, blood pressure, and history of smoking, drinking, and CVD. …”
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    Low density lipoprotein cholesterol and all-cause mortality rate: findings from a study on Japanese community-dwelling persons
  16. 100836
    “…This tailored approach would contribute to avoid useless radiation exposure and preserve renal function of patients.…”
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    Limited benefit of additional contrast-enhanced CT to end-of-treatment PET/CT evaluation in patients with follicular lymphoma
  17. 100837
    “…RESULTS: In the present study, the expression of circ_0007059 in type I interferon (IFN)-treated renal mesangial cells (RMCs), lupus nephritis (LN) specimens, and HEK293 cells was downregulated compared with that in normal healthy samples and untreated cells. …”
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    Circular RNA-0007059 protects cell viability and reduces inflammation in a nephritis cell model by inhibiting microRNA-1278/SHP-1/STAT3 signaling
  18. 100838
    por Garam, Nóra, Cserhalmi, Marcell, Prohászka, Zoltán, Szilágyi, Ágnes, Veszeli, Nóra, Szabó, Edina, Uzonyi, Barbara, Iliás, Attila, Aigner, Christof, Schmidt, Alice, Gaggl, Martina, Sunder-Plassmann, Gere, Bajcsi, Dóra, Brunner, Jürgen, Dumfarth, Alexandra, Cejka, Daniel, Flaschberger, Stefan, Flögelova, Hana, Haris, Ágnes, Hartmann, Ágnes, Heilos, Andreas, Mueller, Thomas, Rusai, Krisztina, Arbeiter, Klaus, Hofer, Johannes, Jakab, Dániel, Sinkó, Mária, Szigeti, Erika, Bereczki, Csaba, Janko, Viktor, Kelen, Kata, Reusz, György S., Szabó, Attila J., Klenk, Nóra, Kóbor, Krisztina, Kojc, Nika, Knechtelsdorfer, Maarten, Laganovic, Mario, Lungu, Adrian Catalin, Meglic, Anamarija, Rus, Rina, Kersnik Levart, Tanja, Macioniene, Ernesta, Miglinas, Marius, Pawłowska, Anna, Stompór, Tomasz, Podracka, Ludmila, Rudnicki, Michael, Mayer, Gert, Rysava, Romana, Reiterova, Jana, Saraga, Marijan, Seeman, Tomáš, Zieg, Jakub, Sládková, Eva, Stajic, Natasa, Szabó, Tamás, Capitanescu, Andrei, Stancu, Simona, Tisljar, Miroslav, Galesic, Kresimir, Tislér, András, Vainumäe, Inga, Windpessl, Martin, Zaoral, Tomas, Zlatanova, Galia, Józsi, Mihály, Csuka, Dorottya
    Publicado 2021
    “…Low serum FHR-5 concentration at presentation associated with better renal survival during the follow-up period; furthermore, it showed clear association with signs of complement overactivation and clinically meaningful clusters. …”
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    FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy
  19. 100839
    “…The second outcomes included 30-day mortality, ICU mortality, In-hospital mortality, ICU length of stay, hospital length of stay, creatinine highest before discharge (mg/dl) and needs for renal replacement therapy (RRT). RESULTS: A total of nine randomized controlled trials involving 19,578 critical ill patients fulfilled the inclusion criteria. …”
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    Balanced crystalloids versus saline in critically ill patients: The PRISMA study of a meta-analysis
  20. 100840
    “…It is currently approved for the treatment of metastatic renal cell carcinoma, hepatocellular carcinoma and medullary thyroid carcinoma. …”
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    CABOCOL-01 trial: a single-arm phase II study assessing safety and efficacy of Cabozantinib for advanced or metastatic cervical carcinoma after platinum treatment failure
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