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  1. 100881
    “…Chronic hyperglycemia can lead to many complications such as increased incidence of cardiovascular diseases as well as renal and ophthalmologic complications. Physical exercise is seen as an effective non-pharmacological strategy for managing the disease. …”
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    High-Intensity Interval Training Improves Cardiac Autonomic Function in Patients with Type 2 Diabetes: A Randomized Controlled Trial
  2. 100882
    “…There was no significant difference in the incidence of pneumonia, urinary tract infection (UTI), hemorrhagic transformation (HT), gastrointestinal bleeding (GIB), seizures or renal insufficiency (RI) among the four groups (P > 0.05). …”
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    Increased admission serum total bile acids can be associated with decreased 3-month mortality in patients with acute ischemic stroke
  3. 100883
    “…The MITRE study will explore and validate a microbiome signature in a larger scale prospective study across several different cancer types. METHODS: Melanoma, renal cancer and non-small cell lung cancer patients who are planned to receive standard immune checkpoint inhibitors are being recruited to the MITRE study. …”
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    The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy
  4. 100884
    “…Subjects will receive a single loading dose of 4500 mg of vigabatrin (or dose adjusted in moderate and severe renal impairment) via enteric tube within 48 h of PASE onset. …”
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    Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol
  5. 100885
    “…Those who died within 12 months were older and had more hypertension, diabetes, chronic renal disease, and malignancy. There was a significant reduction in the total average annual HCU costs of the entire study population 12 months after the first HFU visit [$12 675 (±17 210) after vs. $13 188 (±15 011) before, P = 0.014]. …”
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    The impact of a community‐based heart failure multidisciplinary team clinic on healthcare utilization and costs
  6. 100886
    “…Five of the ten most important features for XGBoost were markedly less important for the traditional logistic regression model: male sex, prior hip fracture, cardiorespiratory failure, acute renal failure, and dialysis status. CONCLUSION: We report a ML algorithm for prediction of major perioperative complications after ankle arthrodesis. …”
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    Development of a Machine Learning Algorithm for Prediction of Complications after Ankle Arthrodesis
  7. 100887
    “…The most active extract and andrographolide were further investigated in a hyperuricemic rat model induced by potassium oxonate to determine serum uric acid levels, liver XO activity, followed by Western blot analysis for renal urate transporter URAT1, GLUT9, and OAT1 to investigate the excretion of uric acid via kidney. …”
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    Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation
  8. 100888
    “…Negatively associated factors were: edema (1.21 [1.07–1.37]); physical therapy (1.21 [1.12–1.31]); nutritional intervention (1.21 [1.14–1.28]) within 1 month before/after start of first line; thrombosis (1.13 [1.04–1.23]); renal disease (1.11 [1.02–1.21]); age (1.07 [1.02–1.13]); and peritoneal metastasis/ascites (1.06 [1.01–1.13]). …”
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    Treatment Pattern for Advanced Gastric Cancer in Japan and Factors Associated with Sequential Treatment: A Retrospective Administrative Claims Database Study
  9. 100889
    “…BACKGROUND: Acute kidney injury (AKI) is a common complication in patients hospitalized with COVID-19 and may require renal replacement therapy (RRT). Dipstick urinalysis is frequently obtained, but data regarding the prognostic value of hematuria and proteinuria for kidney outcomes is scarce. …”
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    Using dipstick urinalysis to predict development of acute kidney injury in patients with COVID-19
  10. 100890
    “…Hypertension, nervous-system involvement, treatment non-compliance, and lower eGFR at diagnosis were independent risk factors for poor prognosis of kidney outcomes. Compared with renal remission rate and cumulative overall survival rate, the proportion of targets achieved was not ideal, suggesting T2T strategy should be used to guide pLN management. …”
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    Clinical manifestations, prognosis, and treat-to-target assessment of pediatric lupus nephritis
  11. 100891
    “…Plasma traumatic acid concentrations were also positively correlated with the presence of hypertension (r = 0.25, P = 0.034), glucose AC (r = 0.34, P = 0.0035), creatinine (r = 0.40, P = 0.0006), and GDF‐15 levels (r = 0.25, P = 0.0376), but negatively correlated with the Modification of Diet in Renal Disease‐simplify‐glomerular filtration rate (r = −0.50, P < 0.0001). …”
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    Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics‐based approach
  12. 100892
    “…RESULTS: Current guidelines generally aligned with PREDICT-FD on indicators of renal involvement, but most lacked specificity regarding cardiac indicators. …”
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    Do clinical guidelines facilitate or impede drivers of treatment in Fabry disease?
  13. 100893
    “…Ao longo da internação, cursou com múltiplas complicações como infecção de corrente sanguínea, candidemia, pneumonia associada à ventilação, insuficiência renal aguda, infecção intestinal por Schistosoma mansoni e Giardia lamblia e TRALI - lesão pulmonar aguda associada à transfusão. …”
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    PULSOTERAPIA COM METILPREDNISOLONA NA SÍNDROME DE HIPERFERRITINEMIA DA COVID-19. RELATO DE DOIS CASOS
  14. 100894
    “…Main time-to-event efficacy outcomes were a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or hospitalization for heart failure, and a composite of kidney failure, a sustained ≥57% decrease in estimated glomerular filtration rate from baseline over ≥4 weeks, or renal death. Among 13 026 patients with a median follow-up of 3.0 years (interquartile range 2.3–3.8 years), the composite cardiovascular outcome occurred in 825 (12.7%) patients receiving finerenone and 939 (14.4%) receiving placebo [hazard ratio (HR), 0.86; 95% confidence interval (CI), 0.78–0.95; P = 0.0018]. …”
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    Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis
  15. 100895
    “…Increased patient volume of distribution and renal function variability within the ICU population adds complexity to vancomycin pharmacokinetics. …”
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    P37 Variable adherence to and effectiveness of a vancomycin continuous infusion protocol within ICUs at a London tertiary-care hospital: a single-centre retrospective service evaluation
  16. 100896
    “…Nineteen had unstable renal function, including one receiving intermittent haemodialysis. …”
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    P17 Vancomycin therapeutic drug monitoring—a call for change?
  17. 100897
    “…In severe cases, it leads to bladder detrusor dysfunction, resulting in dysuria, frequent urination, urgent urination, incomplete urination, and other symptoms including renal function injury. An operation to restore normal urination function and to control postoperative complications, as far as possible, is the most common method for benign prostatic disease. …”
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    Effect of precise nursing service mode on postoperative urinary incontinence prevention in patients with prostate disease
  18. 100898
    por Satyanarayana, Gowri, Enriquez, Kyle T, Sun, Tianyi, Klein, Elizabeth J, Abidi, Maheen, Advani, Shailesh M, Awosika, Joy, Bakouny, Ziad, Bashir, Babar, Berg, Stephanie, Bernardes, Marilia, Egan, Pamela C, Elkrief, Arielle, Feldman, Lawrence E, Friese, Christopher R, Goel, Shipra, Gomez, Cyndi Gonzalez, Grant, Keith L, Griffiths, Elizabeth A, Gulati, Shuchi, Gupta, Shilpa, Hwang, Clara, Jain, Jayanshu, Jani, Chinmay, Kaltsas, Anna, Kasi, Anup, Khan, Hina, Knox, Natalie, Koshkin, Vadim S, Kwon, Daniel H, Labaki, Chris, Lyman, Gary H, McKay, Rana R, McNair, Christopher, Nagaraj, Gayathri, Nakasone, Elizabeth S, Nguyen, Ryan, Nonato, Taylor K, Olszewski, Adam J, Panagiotou, Orestis A, Puc, Matthew, Razavi, Pedram, Robilotti, Elizabeth V, Santos-Dutra, Miriam, Schmidt, Andrew L, Shah, Dimpy P, Shah, Sumit A, Vieira, Kendra, Weissmann, Lisa B, Wise-Draper, Trisha M, Wu, Ulysses, Wu, Julie Tsu-Yu, Choueiri, Toni K, Mishra, Sanjay, Warner, Jeremy L, French, Benjamin, Farmakiotis, Dimitrios
    Publicado 2022
    “…The adjusted risk of any coinfection was positively associated with age >50 years, male sex, cardiovascular, pulmonary, and renal comorbidities, diabetes, hematologic malignancy, multiple malignancies, Eastern Cooperative Oncology Group Performance Status, progressing cancer, recent cytotoxic chemotherapy, and baseline corticosteroids; the adjusted risk of superinfection was positively associated with tocilizumab administration. …”
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    Coinfections in Patients With Cancer and COVID-19: A COVID-19 and Cancer Consortium (CCC19) Study
  19. 100899
    “…Secondary outcomes: Time to initiation of renal replacement therapy or death, neuron-specific enolase (NSE) level at 48 h, MOCA score at day 90, Modified Ranking Scale (mRS) and CPC at 3 months, NT-pro-BNP at 90 days, eGFR and LVEF at 90 days, daily cumulated vasopressor requirement during ICU stay, and need for a combination of vasopressors and inotropic agents or mechanical circulatory support. …”
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    The “Blood pressure and oxygenation targets in post resuscitation care, a randomized clinical trial”: design and statistical analysis plan
  20. 100900
    “…A total of 236 (23.8%) patients suffered postoperative stage 3 AKI including 165 patients who required renal replacement therapy. Advanced age (odds ratio [OR] 1.031; 95% confidence interval [CI] 1.005–1.057; P = 0.018), prolonged cardiopulmonary bypass (CPB) duration (OR 1.010; 95% CI 1.002–1.018; P = 0.013), and higher drainage volume 24 h after surgery (OR 1.000; 95% CI 1.000–1.001; P = 0.033) were identified as independent risk factors for developing stage 3 AKI. …”
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    Identification of risk factors for postoperative stage 3 acute kidney injury in patients who received surgical repair for acute type A aortic dissection
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