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101261por Self, Wesley H., Evans, Christopher S., Jenkins, Cathy A., Brown, Ryan M., Casey, Jonathan D., Collins, Sean P., Coston, Taylor D., Felbinger, Matthew, Flemmons, Lisa N., Hellervik, Susan M., Lindsell, Christopher J., Liu, Dandan, McCoin, Nicole S., Niswender, Kevin D., Slovis, Corey M., Stollings, Joanna L., Wang, Li, Rice, Todd W., Semler, Matthew W.“…DESIGN, SETTING, AND PARTICIPANTS: This study was a subgroup analysis of adults with DKA in 2 previously reported companion trials—Saline Against Lactated Ringer’s or Plasma-Lyte in the Emergency Department (SALT-ED) and the Isotonic Solutions and Major Adverse Renal Events Trial (SMART). These trials, conducted between January 2016 and March 2017 in an academic medical center in the US, were pragmatic, multiple-crossover, cluster, randomized clinical trials comparing balanced crystalloids vs saline in emergency department (ED) and intensive care unit (ICU) patients. …”
Publicado 2020
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101262“…METHODS: Retrospective cohort study using UK Renal Registry and UK Transplant Registry data, including patients aged < 30 years transplanted 1998–2014. …”
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101263por Goodacre, Steve, Thomas, Ben, Lee, Ellen, Sutton, Laura, Loban, Amanda, Waterhouse, Simon, Simmonds, Richard, Biggs, Katie, Marincowitz, Carl, Schutter, Jose, Connelly, Sarah, Sheldon, Elena, Hall, Jamie, Young, Emma, Bentley, Andrew, Challen, Kirsty, Fitzsimmons, Chris, Harris, Tim, Lecky, Fiona, Lee, Andrew, Maconochie, Ian, Walter, Darren“…Outcomes were admission to hospital, COVID-19 result, organ support (respiratory, cardiovascular or renal), and death, by record review at 30 days. Mean age was 58.4 years, 11200 (50.4%) were female and 11034 (49.6%) male. …”
Publicado 2020
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101264por Headley, Samuel A., Chapman, Donna J., Germain, Michael J., Evans, Elizabeth E., Hutchinson, Jasmin, Madsen, Karen L., Ikizler, Talat Alp, Miele, Emily M., Kirton, Kristyn, O’Neill, Elizabeth, Cornelius, Allen, Martin, Brian, Nindl, Bradley, Vaziri, Nosratola D.“…Supplementation with high amylose maize resistant starch type 2 (RS-2) can change the composition of the gut microbiota, and reduce markers of inflammation and oxidative stress in patients with end-stage renal disease. However, the impact of RS-2 supplementation has not been extensively studied in CKD patients not on dialysis. …”
Publicado 2020
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101265por Piron, Sarah, Verhoeven, Jeroen, Descamps, Benedicte, Kersemans, Ken, De Man, Kathia, Van Laeken, Nick, Pieters, Leen, Vral, Anne, Vanhove, Christian, De Vos, Filip“…Ex vivo biodistribution demonstrated fast renal clearance of (18)F-PSMA-11 as well as no significant increase in bone uptake.…”
Publicado 2020
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101266por Schrauben, Sarah J., Chen, Hsiang-Yu, Lin, Eugene, Jepson, Christopher, Yang, Wei, Scialla, Julia J., Fischer, Michael J., Lash, James P., Fink, Jeffrey C., Hamm, L. Lee, Kanthety, Radhika, Rahman, Mahboob, Feldman, Harold I., Anderson, Amanda H.“…METHODS AND FINDINGS: Data from 3,939 participants enrolled in the Chronic Renal Insufficiency Cohort (CRIC) Study between 2003 and 2008 at 7 clinical centers in the United States were used to estimate primary causes of hospitalizations, hospitalization rates, and baseline participant factors associated with all-cause, cardiovascular, and non-cardiovascular hospitalizations during a median follow up of 9.6 years. …”
Publicado 2020
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101267por Musso, Giovanni, Sircana, Antonio, Saba, Francesca, Cassader, Maurizio, Gambino, Roberto“…We conducted a meta-analysis and meta-regression of randomized controlled trials (RCTs) evaluating SGLT2i in T1DM to assess moderators of the relative risk (RR) of DKA, of glycemic (HbA1c, fasting plasma glucose, continuous glucose monitoring parameters, insulin dose, and insulin sensitivity indices) and non-glycemic (body mass index (BMI), systolic BP, renal function, albuminuria, and diabetic eye disorders) efficacy, and of other safety outcomes (including hypoglycemia, infections, major adverse cardiovascular events, and death). …”
Publicado 2020
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101268por Dagnew, Alemnew F, Vink, Peter, Drame, Mamadou, Willer, David, Salaun, Bruno, Schuind, Anne“…METHODS: Our analysis includes five phase I/II/III clinical trials conducted worldwide between 2010–2017 (Table 1) in IC populations (autologous HSCT, human immunodeficiency virus [HIV]-infected, HM, solid tumor [ST] on chemotherapy and renal transplant [RT] patients) ≥ 18 YOA. Anti-glycoprotein E (gE) antibody geometric mean concentrations (GMCs) and gE-specific CD4 T cell frequencies were descriptively evaluated by age group (18–49 YOA and ≥ 50 YOA) and overall at 1 month (M) and 12M post-last RZV dose. …”
Publicado 2020
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101269por Khawaja, Fareed, Mullane, Kathleen, El Haddad, Lynn, Sassine, Joseph, Heredia, Ella Ariza, Tang, Yuexin, Raval, Amit D, Chemaly, Roy F“…Acute kidney injury was the most frequent CMV treatment-related complication (67%) followed by myelosuppression (55%) and end-stage renal disease (36%). Of 56 encounters, 16% required admission to intensive care unit with a median duration of 9 days. …”
Publicado 2020
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101270por Chan, Kok Hoe, Patel, Bhavik, Ajao, Susanne O, Ramahi, Amr, Szabela, Maria E, Slim, Jihad“…There is limited data on the epidemiology and prognosis of COVID-19 in end stage renal disease (ESRD) patients on hemodialysis (HD). …”
Publicado 2020
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101271por Dake, Michael D., Fanelli, Fabrizio, Lottes, Aaron E., O’Leary, Erin E., Reichert, Heidi, Jiang, Xiaohui, Fu, Weiguo, Iida, Osamu, Zen, Kan, Schermerhorn, Marc, Zeller, Thomas, Ansel, Gary M.“…Factors potentially associated with TLR (sex, age, diabetes, hypertension, hypercholesterolemia, renal disease, smoking status, Rutherford classification, lesion length, reference vessel diameter (RVD), popliteal involvement, total occlusion, calcification severity, prior interventions, and number of runoff vessels) were analyzed in a Cox proportional hazards model. …”
Publicado 2020
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101272“…DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study used data from the Chronic Renal Insufficiency Cohort, a multicenter cohort study of participants with chronic kidney disease (CKD). …”
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101273por Yamada, Yosuke, Harada, Makoto, Hara, Yuuta, Iwabuchi, Ryohei, Hashimoto, Koji, Yamamoto, Shuhei, Kamijo, Yuji“…Focusing on the early treatment phases, PE was associated with a reduction in end-stage renal disease incidence compared with both no PE (PE 1/43 vs. no PE 10/41; RR 0.14 [0.03–0.77] at 3 months) and pulse steroid (PE 11/70 vs. pulse steroid 23/67; RR 0.46 [0.24–0.86] at 3 months). …”
Publicado 2021
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101274por Mukhtar, Noha N, Abouzied, Mohei El-Din M, Alqahtani, Mohammed H, Hammami, Muhammad M“…Bone mineral density and renal ultrasound were normal. Parathyroid ultrasound showed two hypoechoic nodules inferior to the left and right thyroid lobes; however, (99m)technitium-sestamibi scans (2013, 2016, 2018) were negative. …”
Publicado 2021
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101275“…The deceased group had more patients with hypertension (50.0% vs. 23.0, p = 0.006), diabetes mellitus (35.6% vs. 10.6%, p = 0.002), cardiovascular diseases (23.1% vs. 4.4%, p = 0.001), chronic renal insufficiency (11.5% vs. 0.9%, p = 0.003) and atrial fibrillation (7.7% vs 0%, p = 0.003). …”
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101276por Albasri, Ali, Hattle, Miriam, Koshiaris, Constantinos, Dunnigan, Anna, Paxton, Ben, Fox, Sarah Emma, Smith, Margaret, Archer, Lucinda, Levis, Brooke, Payne, Rupert A, Riley, Richard D, Roberts, Nia, Snell, Kym I E, Lay-Flurrie, Sarah, Usher-Smith, Juliet, Stevens, Richard, Hobbs, F D Richard, McManus, Richard J, Sheppard, James P“…These data could be used to inform shared decision making between doctors and patients about initiation and continuation of antihypertensive treatment, especially in patients at high risk of harm because of previous adverse events or poor renal function. REGISTRATION: PROSPERO CRD42018116860.…”
Publicado 2021
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101277por Ligero, Marta, Jordi-Ollero, Olivia, Bernatowicz, Kinga, Garcia-Ruiz, Alonso, Delgado-Muñoz, Eric, Leiva, David, Mast, Richard, Suarez, Cristina, Sala-Llonch, Roser, Calvo, Nahum, Escobar, Manuel, Navarro-Martin, Arturo, Villacampa, Guillermo, Dienstmann, Rodrigo, Perez-Lopez, Raquel“…The multi-centric retrospective clinical study included CT scans of patients with colorectal/renal cancer liver metastases. Ninety-three radiomics features of first order and texture were extracted. …”
Publicado 2020
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101278por Myat, Aung, Redwood, Simon R., Arri, Satpal, Gersh, Bernard J., Bhatt, Deepak L., Marber, Michael S.“…Liraglutide did not cause symptomatic hypoglycaemia, renal dysfunction, acute pancreatitis or provoke early withdrawal from the trial. …”
Publicado 2021
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101279por Zelniker, Thomas A., Ardissino, Maddalena, Andreotti, Felicita, O’Donoghue, Michelle L., Yin, Ophelia, Park, Jeong-Gun, Murphy, Sabina A., Ruff, Christian T., Lanz, Hans J., Antman, Elliott M., Braunwald, Eugene, Giugliano, Robert P., Merlini, Piera Angelica“…RESULTS: In comparison with men, women were older, had lower body weight, were more likely to have hypertension and renal dysfunction, but less likely to smoke, drink alcohol, or have diabetes or coronary artery disease. …”
Publicado 2021
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101280por Bakhshandeh, Behnaz, Sorboni, Shokufeh Ghasemian, Javanmard, Amir-Reza, Mottaghi, Seyed Saeed, Mehrabi, Mohammad-reza, Sorouri, Farzaneh, Abbasi, Ardeshir, Jahanafrooz, Zohreh“…The ACE2 has a crucial role in vascular, renal, and myocardial physiology. Genetic factors contributing to the outcome of SARS-CoV-2 infection are unknown; however, variants in the specific sites of ACE2 gene could be regarded as a main genetic risk factor for COVID-19. …”
Publicado 2021
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