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  1. 101281
    “…Diabetes was a significant predictor of mortality and hospitalization for heart failure (HR: 1.72 [1.1–2.6], p = 0.011, adjusted for age, BMI, NYHA class and renal function). In diabetic patients, lower levels of glycated hemoglobin (HbA1C < 7%) were associated with worse prognosis (HR: 2.07 [1.1–4.0], p = 0.028 adjusted for age, BMI, hemoglobin and NT-proBNP levels). …”
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    Diabetic phenotype and prognosis of patients with heart failure and preserved ejection fraction in a real life cohort
  2. 101282
    “…Fifty-one type 2 diabetes patients (mean age 62 ± 13 years) with a high rate of hypertension and no renal insufficiency were analyzed. Pemafibrate 0.2 mg (0.1 mg twice daily) was administered, and serum lipids were monitored every 4–8 weeks from 8 weeks before administration to 24 weeks after administration. …”
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    Pemafibrate decreases triglycerides and small, dense LDL, but increases LDL-C depending on baseline triglycerides and LDL-C in type 2 diabetes patients with hypertriglyceridemia: an observational study
  3. 101283
    “…Lipid profiles and urine albumin–creatinine ratio were measured. Renal and aortic histopathologic alterations were analyzed. …”
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    Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice
  4. 101284
    por Estella, Á., Garcia Garmendia, J.L., de la Fuente, C., Machado Casas, J.F., Yuste, M.E., Amaya Villar, R., Estecha, M.A., Yaguez Mateos, L., Cantón Bulnes, M.L., Loza, A., Mora, J., Fernández Ruiz, L., Díez del Corral Fernández, B., Rojas Amezcua, M., Rodriguez Higueras, M.I., Díaz Torres, I., Recuerda Núñez, M., Zaheri Beryanaki, M., Rivera Espinar, F., Matallana Zapata, D.F., Moreno Cano, S.G., Gimenez Beltrán, B., Muñoz, N., Sainz de Baranda Piñero, A., Bustelo Bueno, P., Moreno Barriga, E., Rios Toro, J.J., Pérez Ruiz, M., Gómez González, C., Breval Flores, A., de San José Bermejo Gómez, A., Ruiz Cabello Jimenez, M.A., Guerrero Marín, M., Ortega Ordiales, A., Tejero-Aranguren, J., Rodriguez Mejías, C., Gomez de Oña, J., de la Hoz, C., Ocaña Fernández, D., Ibañez Cuadros, S., Garnacho Montero, J.
    Publicado 2022
    “…CONCLUSION: Age, APACHE II, SOFA > value of 6 points, along with vasopressor requirements or renal replacement therapy have been identified as predictor factors of mortality at six weeks. …”
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    Predictive factors of six-week mortality in critically ill patients with SARS-CoV-2: A multicenter prospective study
  5. 101285
    “…METHODS: In this retrospective surveillance study, patients who met the US Centers for Disease Control and Prevention (CDC) case definition for MIS-C (younger than 21 years, fever, laboratory evidence of inflammation, admitted to hospital, multisystem [≥2] organ involvement [cardiac, renal, respiratory, haematological, gastrointestinal, dermatological, or neurological], no alternative plausible diagnosis, and either laboratory confirmation of SARS-CoV-2 infection by RT-PCR, serology, or antigen test, or known COVID-19 exposure within 4 weeks before symptom onset) were reported from state and local health departments to the CDC using standard case-report forms. …”
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    Factors linked to severe outcomes in multisystem inflammatory syndrome in children (MIS-C) in the USA: a retrospective surveillance study
  6. 101286
    “…The patients were divided into four anatomic main groups (infrarenal (endo: n = 94; open: n = 88), juxta- and para-renal (open n = 84), thoraco-abdominal (open n = 13) and thoracic (endo: n = 11; open: n = 6). …”
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    Evaluation of metabolic equivalents of task (METs) in the preoperative assessment in aortic repair
  7. 101287
    “…We tested this hypothesis in patients with type 2 diabetes from the Renal Insufficiency And Cardiovascular Events Italian Multicentre Study. …”
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    Insulin resistance, diabetic kidney disease, and all-cause mortality in individuals with type 2 diabetes: a prospective cohort study
  8. 101288
    “…Acute kidney injury (AKI) developed in 46 (42.2%) patients, and 4 (3.7%) of the patients required renal replacement therapy (RRT). A total of 22 (20.2%) patients were admitted in the ICU, and 19 (17.4%) patients required invasive mechanical ventilation. 14 (12.8%) of the patients died. …”
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    Predicting the outcome of COVID-19 infection in kidney transplant recipients
  9. 101289
    “…We found patients complicated with heart failure (HF)[hazard ratio (HR) 1.10, 95% confidence interval (CI) 1.02–1.18], established coronary artery disease (CAD) (HR 1.24, 95%CI 1.17–1.33), ischemic stroke/transient ischemic attack (TIA) (HR 1.22, 95%CI 1.15–1.30), diabetes (HR 1.14, 95%CI 1.08–1.20), chronic obstructive pulmonary disease (COPD) (HR 1.28, 95%CI 1.02–1.62), gastrointestinal disorder (HR 1.37, 95%CI 1.21–1.55), and renal dysfunction (HR 1.24, 95%CI 1.09–1.42) had higher risks of hospitalization. …”
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    Incidence and predictors of hospitalization in patients with atrial fibrillation: results from the Chinese atrial fibrillation registry study
  10. 101290
    por Broberg, Craig S., Kovacs, Adrienne H., Sadeghi, Soraya, Rosenbaum, Marlon S., Lewis, Matthew J., Carazo, Matthew R., Rodriguez, Fred H., Halpern, Dan G., Feinberg, Jodi, Galilea, Francisca Arancibia, Baraona, Fernando, Cedars, Ari M., Ko, Jong M., Porayette, Prashob, Maldonado, Jennifer, Sarubbi, Berardo, Fusco, Flavia, Frogoudaki, Alexandra A., Nir, Amiram, Chaudhry, Anisa, John, Anitha S., Karbassi, Arsha, Hoskoppal, Arvind K., Frischhertz, Benjamin P., Hendrickson, Benjamin, Bouma, Berto J., Rodriguez-Monserrate, Carla P., Broda, Christopher R., Tobler, Daniel, Gregg, David, Martinez-Quintana, Efren, Yeung, Elizabeth, Krieger, Eric V., Ruperti-Repilado, Francisco J., Giannakoulas, George, Lui, George K., Ephrem, Georges, Singh, Harsimran S., Almeneisi, Hassan MK., Bartlett, Heather L., Lindsay, Ian, Grewal, Jasmine, Nicolarsen, Jeremy, Araujo, John J., Cramer, Jonathan W., Bouchardy, Judith, Al Najashi, Khalid, Ryan, Kristi, Alshawabkeh, Laith, Andrade, Lauren, Ladouceur, Magalie, Schwerzmann, Markus, Greutmann, Matthias, Meras, Pablo, Ferrero, Paolo, Dehghani, Payam, Tung, Poyee P., Garcia-Orta, Rocio, Tompkins, Rose O., Gendi, Salwa M., Cohen, Scott, Klewer, Scott, Hascoet, Sebastien, Mohammadzadeh, Shabnam, Upadhyay, Shailendra, Fisher, Stacy D., Cook, Stephen, Cotts, Timothy B., Aboulhosn, Jamil A.
    Publicado 2021
    “…Factors associated with death included male sex, diabetes, cyanosis, pulmonary hypertension, renal insufficiency, and previous hospital admission for heart failure. …”
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    COVID-19 in Adults With Congenital Heart Disease
  11. 101291
    por Murthy, Srinivas, Archambault, Patrick M., Atique, Anika, Carrier, François Martin, Cheng, Matthew P., Codan, Cassidy, Daneman, Nick, Dechert, William, Douglas, Sarah, Fiest, Kirsten M., Fowler, Robert, Goco, Geraldine, Gu, Yusing, Guerguerian, Anne-Marie, Hall, Richard, Hsu, Jimmy M., Joffe, Ari, Jouvet, Philippe, Kelly, Laurel, Kho, Michelle E., Kruisselbrink, Rebecca J., Kumar, Deepali, Kutsogiannis, Demetrios James, Lamontagne, François, Lee, Todd C., Menon, Kusum, O’Grady, Heather, O’Hearn, Katie, Ovakim, Daniel H., Pharand, Scott G., Pitre, Tyler, Reel, Riley, Reeve, Brenda, Rewa, Oleksa, Richardson, David, Rishu, Asgar, Sandhu, Gyan, Sarfo-Mensah, Shirley, Shadowitz, Ellen, Sligl, Wendy, Solomon, Joshua, Stelfox, Henry T., Swanson, Ashleigh, Tessier-Grenier, Hubert, Tsang, Jennifer L.Y., Wood, Gordon
    Publicado 2021
    “…Critically ill patients received treatment with invasive mechanical ventilation (88.8%), renal replacement therapy (14.9%) and extracorporeal membrane oxygenation (4.0%); 26.2% died. …”
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    Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study
  12. 101292
    “…NSC765598 displayed selective antiproliferative and cytotoxic preferences for NSCLC (50% growth inhibition (GI(50)) = 1.12–3.95 µM; total growth inhibition (TGI) = 3.72–16.60 μM), leukemia (GI(50) = 1.20–3.10 µM; TGI = 3.90–12.70 μM), melanoma (GI(50) = 1.45–3.59 µM), and renal cancer (GI(50) = 1.38–3.40 µM; TGI = 4.84–13.70 μM) cell lines, while panels of colon, breast, ovarian, prostate, and central nervous system (CNS) cancer cell lines were less sensitive to NSC765598. …”
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    mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications
  13. 101293
    “…In the case of [(177)Lu]Lu-6S-RedFol-1, also the kidney uptake was increased; however, renal retention of [(177)Lu]Lu-6R-RedFol-1 was similar to that of [(177)Lu]Lu-OxFol-1. …”
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    Preclinical evaluation of 5-methyltetrahydrofolate-based radioconjugates—new perspectives for folate receptor–targeted radionuclide therapy
  14. 101294
    “…BACKGROUND: Acute kidney injury (AKI) is associated with high morbidity and mortality in dogs, but diagnosis may be impaired due the insensitivity of routine renal function biomarkers to detect earlier or milder forms of injury. …”
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    Serial serum creatinine, SDMA and urinary acute kidney injury biomarker measurements in dogs envenomated by the European adder (Vipera berus)
  15. 101295
    “…Decellularized BCA chips were seeded with human ECFC, isolated from a high cardiovascular risk patient group, suffering from diabetes, hypertension and/or chronic renal failure. ECFC were cultured alone or in coculture with rat or human mesenchymal stromal cells (rMSC/hMSC). …”
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    In vitro recellularization of decellularized bovine carotid arteries using human endothelial colony forming cells
  16. 101296
    “…GLP-1 RAs may also help prevent renal complications of type 2 diabetes. Other active research areas in the field of GLP-1 RAs are the definition of subgroups within the type 2 diabetes population who particularly benefit from treatment with GLP-1 RAs. …”
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    GLP-1 receptor agonists in the treatment of type 2 diabetes – state-of-the-art
  17. 101297
    “…Past medical history included a renal calculus three years earlier. His serum corrected calcium on admission was elevated at 2.87mmol/L (2.10-2.60mmol/L). …”
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    Post-Traumatic Heterotopic Ossification With Incidental Hyperparathyroidism
  18. 101298
    “…During the progression study, two months later, the patient was admitted to the hospital for severe hypoK(+) (1.7 mEq / L), normal renal function and metabolic alkalosis. Although abiraterone was discontinued, up to 460 mEq iv per day of K(+) and spironolactone were required to maintain serum K(+) above 2.5. 3 days later, the hormonal study revealed TSH 1.13 mU /L, ACTH 162 pmol/L, cortisol 258 nmol/L, aldosterone 105 pmol/L, renin (protein) 0.7 µU/mL and deoxycorticosterone 507 pmol/L. 11 days later, plasma cortisol was 967 nmol/L, ACTH 132pmol/L, and cortisoluria 1456 nmol/d. …”
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    Late Onset of Abiraterone Severe Hypokalemia Due to Unsuspected ACTH-Secreting NEC
  19. 101299
    “…Introduction: TIO is a rare paraneoplastic syndrome characterised by renal phosphate wasting due to fibroblast growth factor-23 (FGF23) over-secretion from a phosphaturic mesenchymal tumour (PMT). …”
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    Successful Medical Management of a Non-Localising Case of Tumour-Induced Osteomalacia
  20. 101300
    “…Medical history included renal transplant due to ESRD from IgA nephropathy, DM and treated latent TB with no prior or family history of thyroid disease. …”
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    Tuberculous Thyroiditis Post COVID-19 Infection
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