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101401por Stern, Edward P., Host, Lauren V., Wanjiku, Ivy, Escott, K. Jane, Gilmour, Peter S., Ochiel, Rachel, Unwin, Robert, Burns, Aine, Ong, Voon H., Cadiou, Helen, O’Keeffe, Aidan G., Denton, Christopher P.“…METHODS: This trial included three sub-studies: ZEBRA 1—a randomised placebo-controlled, double-blind trial of zibotentan in SSc patients with CKD2 or CKD3 (and glomerular filtration rate (GFR) >45 ml/min) over 26 weeks; ZEBRA 2A—a 26-week placebo-controlled, single-blind trial of zibotentan in scleroderma renal crisis patients not requiring dialysis; and ZEBRA 2B—an open label pharmacokinetic study of zibotentan in patients on haemodialysis. …”
Publicado 2022
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101402por Cui, Yiyan, Tian, Zhimei, Yu, Miao, Deng, Dun, Lu, Huijie, Song, Min, Ma, Xianyong, Wang, Limin“…The hepatic γ-amino-n-butyric acid content increased linearly and quadratically (P < 0.001), while the carnosine content decreased (quadratic, P = 0.004). The contents of renal arginine, proline, cystine, glutamate, and total amino acids (TAA) decreased quadratically (P < 0.05), but the contents of glycine (quadratic, P = 0.015) and γ-amino-n-butyric acid (linear, P = 0.008) increased. …”
Publicado 2022
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101403por Kao, Pei‐Yu, Yeh, Hung‐Chieh, Hsia, Ying‐Fang, Hsiao, Ya‐Luan, Wang, Jie‐Sian, Chang, David Ray, Chang, Shih‐Ni, Chiang, Hsiu‐Yin, Kuo, Chin‐Chi“…Three GFR estimation equations [the Chronic Kidney Disease Epidemiology Collaboration (CKD‐EPI), Modification of Diet in Renal Disease (MDRD) Study, and Taiwanese MDRD], 24‐h CrCl, and 24‐h U‐CER–adjusted eGFR were used. …”
Publicado 2022
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101404por Wang, Kai, Shi, Xian, Zhu, Ziwei, Hao, Xingjie, Chen, Liangkai, Cheng, Shanshan, Foo, Roger S. Y., Wang, Chaolong“…These clinical factors covered 12 cardiometabolic traits, 13 hematological indices, 7 hepatological and 3 renal function indices, and 2 serum electrolyte indices. …”
Publicado 2022
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101405por Coscas, Raphael, Dubosq, Maxime, Charton, Johanna, El Batti, Salma, Gaudric, Julien, Koskas, Fabien, Chiche, Laurent, Couture, Thibault, Davaine, Jean-Michel, Castier, Yves, Cerceau, Pierre, EL Hajjam, Mostafa, Samb, Patricia, Beauchet, Alain, Grimaldi, Lamiae, Javerliat, Isabelle, Goeau-Brissonniere, Olivier, Alsac, Jean-Marc, Onorati, Ilaria, Martinod, Emmanuel, Desgranges, Pascal, Touma, Joseph, Cochennec, Frédéric, Pellenc, Quentin, Julia, Pierre, Coggia, Marc“…The sites of COV-AT were the lower extremities (n = 35%, 58%), the abdominal aorta (n = 10%, 17%), the thoracic aorta (n = 7%, 12%), the upper limbs (n = 7%, 12%), the cerebral arteries (n = 7%, 12%), the digestive arteries (n = 6%, 10%), the renal arteries (n = 2%, 3%), and the ophthalmic artery (n = 1%, 2%). …”
Publicado 2022
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101406por Silk, Ann W., Saraiya, Biren, Groisberg, Roman, Chan, Nancy, Spencer, Kristen, Girda, Eugenia, Shih, Weichung, Palmeri, Marisa, Saunders, Tracie, Berman, Robert M., Coric, Vlad, Chen, Suzie, Zloza, Andrew, Vieth, Joshua, Mehnert, Janice M., Malhotra, Jyoti“…RESULTS: We enrolled 14 patients with advanced solid tumors (melanoma = 3, NSCLC = 3, renal cell carcinoma = 2, bladder/urothelial = 2, ovarian cancer = 1, adenoid cystic carcinoma = 1, pleural mesothelial = 1, head and neck cancer = 1). …”
Publicado 2022
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101407por Li, Xuewei, Liu, Jie, Zhao, Yingzhe, Xu, Ning, Lv, E., Ci, Chunzeng, Li, Xiangling“…VitD3-treated mice exhibited significantly improved renal pathological damage and reduced proteinuria, BUN, SCr, A-ds DNA antibody and immune complex deposition levels (P < 0.05) compared with untreated MRL/lpr mice. …”
Publicado 2022
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101408“…General clinical information, indicators for renal function, arterial blood gas analyses, arterial blood lactic acid content (mmol/L), and coagulation indexes at 0 day, 3 days, 7 days, and 11 days after admission were recorded and compared between the two groups. …”
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101409por Dye, Christian K., Corley, Michael J., Ing, Claire, Lum-Jones, Annette, Li, Dongmei, Mau, Marjorie K. L. M., Maunakea, Alika K.“…Unrelenting systemic inflammation frequently leads to a cascade of multiple comorbidities associated with DM, including cardiovascular disease, microvascular complications, and renal dysfunction. Yet few studies have examined the link between chronic inflammation at a cellular level and its relationship to standard DM therapies such as diabetes-specific lifestyle and social support education, well recognized as the cornerstone of clinical standards of diabetes care. …”
Publicado 2022
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101410por Hosseinzadeh, Ali, Sahab-Negah, Sajad, Nili, Sairan, Aliyari, Roqayeh, Goli, Shahrbanoo, Fereidouni, Mohammad, Alami, Ali, Shati, Mohsen, Ahmadnezhad, Elham, Mehravaran, Shiva, Fateh, Mansooreh, Khajeha, Hamidreza, Emamian, Zahra, Behmanesh, Elahe, Mahdavi, Sepideh, Enayatrad, Mostafa, Mangolian shahrbabaki, Parvin, Ansari-Moghaddam, Alireza, Heidarzadeh, Abtin, Shahraki-Sanavi, Fariba, Hashemi Shahri, Seyed Mohammad, Dehghan, Mahlagha, Amini Moridani, Mohammadreza, Sheibani, Hossein, Abbaszadeh, Maryam, Jafari, Reza, Valikhani, Maryam, Binesh, Ehsan, Vahedi, Hamid, Chaman, Reza, Khodashahi, Rozita, Amini, Mahnaz, Jabbari Azad, Farahzad, Rezaeitalab, Fariborz, Amel Jamehdar, Saeid, Eshraghi, Ali, Sharifi, Hamid, Hashemi Bajgani, Seyed Mehdi, Mahdavi, Amin, Jafarzadeh, Abdollah, Farokhnia, Mehrdad, Ebrahimi, Saeedeh, Pardakhti, Abbas, Ghaderi, Ebrahim, Soltani, Hasan, Jadidoleslami, Sedigh, Arianejad, Anoush, Gavili, Hamed, Moradveisi, Borhan, Motamedi, Dina, Zare, Hamed, Kazemi, Toba, Emamian, Mohammad Hassan“…Diabetes and respiratory, cardiac and renal disease were associated with higher risks of contracting COVID-19 after vaccination. …”
Publicado 2022
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101411por Polilli, Ennio, Frattari, Antonella, Esposito, Jessica Elisabetta, D’Amato, Milena, Rapacchiale, Giorgia, D’Intino, Angela, Albani, Alberto, Di Iorio, Giancarlo, Carinci, Fabrizio, Parruti, Giustino“…The strongest predictors were: for hospitalisation, monocyte distribution width ≥ 22 (4.09; 2.21–7.72) and diabetes (OR = 3.04; 1.09–9.84); for oxygen support: saturation < 95% (OR = 11.01; 3.75–41.14), lactate dehydrogenase≥237 U/L (OR = 5.93; 2.40–15.39) and lymphocytes< 1.2 × 10(3)/μL (OR = 4.49; 1.84–11.53); for intensive care, end stage renal disease (OR = 59.42; 2.43–2230.60), lactate dehydrogenase≥334 U/L (OR = 5.59; 2.46–13.84), D-dimer≥2.37 mg/L (OR = 5.18; 1.14–26.36), monocyte distribution width ≥ 25 (OR = 3.32; 1.39–8.50); for death, procalcitonin≥0.2 ng/mL (HR = 2.86; 1.95–4.19) and saturation < 96% (HR = 2.74; 1.76–4.28). …”
Publicado 2022
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101412por Ricci, Fabrizio, Neumann, Johannes T., Rübsamen, Nicole, Sörensen, Nils A., Ojeda, Francisco, Cataldo, Ivana, Zeller, Tanja, Schäfer, Sarina, Hartikainen, Tau S., Golato, Maria, Palermi, Stefano, Zimarino, Marco, Blankenberg, Stefan, Westermann, Dirk, De Caterina, Raffaele“…Both strategies were comparably safe as the ESC 0/1-h dual-sampling algorithm and this was consistent across subgroups of early-comers, low-intermediate risk (GRACE-score < 140) and renal dysfunction. Despite a numerically higher rate of false-negative results, the dual-marker strategy ruled-out a slightly but significantly higher percentage of patients compared with single hs-cTnI determination (37.4% versus 32.9%; P < 0.001). …”
Publicado 2022
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101413por Re Cecconi, Andrea David, Barone, Mara, Gaspari, Simona, Tortarolo, Massimo, Bendotti, Caterina, Porcu, Luca, Terribile, Giulia, Piccirillo, Rosanna“…METHODS: As cancer cachexia models, we used mice bearing colon adenocarcinoma C26, human renal carcinoma RXF393, or Lewis lung carcinoma, with breast cancer 4T1‐injected mice as controls. …”
Publicado 2022
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101414por Baviera, Marta, Foresta, Andreana, Colacioppo, Pierluca, Macaluso, Giulia, Roncaglioni, Maria Carla, Tettamanti, Mauro, Fortino, Ida, Genovese, Stefano, Caruso, Irene, Giorgino, Francesco“…Clinical events were: death, hospital admission for myocardial infarction (MI), stroke, heart failure (HF), and renal disease as individual and composite outcomes (MACE-3: all cause-death, non-fatal MI, non-fatal stroke; MACE-4: MACE-3 plus unstable angina). …”
Publicado 2022
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101415por Chen, Zhehui, Dong, Hui, Liu, Yupeng, He, Ruxuan, Song, Jinqing, Jin, Ying, Li, Mengqiu, Liu, Yi, Liu, Xueqin, Yan, Hui, Qi, Jianguang, Wang, Fang, Xiao, Huijie, Zheng, Hong, Kang, Lulu, Li, Dongxiao, Zhang, Yao, Yang, Yanling“…Further, 46 patients (82.1%) had neuropsychiatric diseases; 11 patients (19.6%), cardiovascular diseases; and 6 patients (10.7%), pulmonary hypertension. Renal damage was observed in 6 cases (10.7%). Genetic analysis revealed 21 variants of the MMACHC gene in the 56 patients. …”
Publicado 2022
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101416por Berry, Crista-Lee Shahine, Melbourne-Chambers, Roxanne Helene, Harrison, Abigail Natalie, Anzinger, Joshua James, Gordon-Johnson, Kelly-Ann Maxorinthia, Deyde, Varough Mohamed, Christie, Celia Dana Claire“…All recovered except one child who was receiving renal replacement therapy and developed myocardial complications. …”
Publicado 2022
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101417por Choudhary, Sidhya, Mishra, Ramesh kumar, Vyas, Aruna, Pathan, Nazneen, Gupta, Karuna“…Patient serum was found negative for HIV, HBV, and HCV. Liver and renal function tests were within normal range and in hematology, ESR was raised (50; normal range:0-20). …”
Publicado 2022
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101418por Rana, Bhaskar, Xess, Immaculata, Singh, Gagandeep, Kumar, Rakesh, Soneja, Manish, Jain, Ashima, Choudhury, Ajay Roy“…RESULTS: Mechanical ventilation, cavitary lung disease, and renal failure with metabolic acidosis were unique risk factors observed for pulmonary co-infection, while use of systemic corticosteroids for treatment of SARS-CoV-2 infection was common in rhino-orbito-cerebral (ROC) or sino-nasal (SN) co-infection. …”
Publicado 2022
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101419por Ali, Nur Aminah Mohamed, Ali, Nursofiah Hassan, Radhakrishnan, Anuradha, Thabit, Alif Adlan Mohd, Sukur, Salina Mohamed, Bahari, Norazlah“…Risk factors namely immunocompromised status, indwelling vascular catheter, abdominal surgeries, renal failure or on dialysis support, polymicrobial usage, and prolonged stay in ICU. …”
Publicado 2022
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101420“…She was anemic with a normal leucocyte count, HIV negative, ESR of 85 mm/h, and CRP of 23 mg/L. Her renal and liver function tests were normal. CT left leg with sinogram showed features of chronic osteomyelitis of left distal femur and proximal tibia with active sinus tract in left tibia. …”
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