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101481por Wang, Jingyun, Zhang, Ping, Liu, Mengyuan, Huang, Zhengrui, Yang, Xiaofeng, Ding, Yuzhen, Liu, Jia, Cheng, Xin, Xu, Shujie, He, Meiyao, Zhang, Fengxiang, Wang, Guang, Li, Ruiman, Yang, Xuesong“…The A2M-overexpression rat model closely mimicked the characteristics of PE (i.e., hypertension in mid-to-late gestation, histological and ultrastructural signs of renal damage, proteinuria, and fetal growth restriction). …”
Publicado 2023
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101482por Uglebjerg, Nicoline, Ahmadizar, Fariba, Aly, Dina M., Cañadas-Garre, Marisa, Hill, Claire, Naber, Annemieke, Oddsson, Asmundur, Singh, Sunny S., Smyth, Laura, Trégouët, David-Alexandre, Chaker, Layal, Ghanbari, Mohsen, Steinthorsdottir, Valgerdur, Ahlqvist, Emma, Hadjadj, Samy, Van Hoek, Mandy, Kavousi, Maryam, McKnight, Amy Jayne, Sijbrands, Eric J., Stefansson, Kari, Simons, Matias, Rossing, Peter, Ahluwalia, Tarunveer S.“…Additional associations with diverse renal function measures (lower cystatin C and higher eGFR(creatinine-cystatin C) levels) and a CUBN-focused GRS further suggests an important role of CUBN in the future personalization of chronic kidney disease management in people without diabetes.…”
Publicado 2023
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101483por Guliciuc, Mădălin, Porav-Hodade, Daniel, Chibelean, Bogdan-Calin, Voidazan, Septimiu Toader, Ghirca, Veronica Maria, Maier, Adrian Cornel, Marinescu, Monica, Firescu, Dorel“…The inclusion criteria were: UTI proven by urine culture or diagnosed clinically complicated with UTO, fever or shaking chills, and purulent collections, such as psoas abscess, Fournier Syndrome, renal abscess, and paraurethral abscess, showing SIRS. …”
Publicado 2023
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101484“…RESULTS: DIP2B was highly expressed in 26 of 33 cancer types and was significantly associated with poor overall survival (OS) in breast invasive carcinoma (BRCA), mesothelioma and chromophobe renal cell carcinoma (each P < 0.05). DIP2B showed a negative correlation with the immune score, the infiltration levels of key immune killer cells (CD8 + T cells, activated NK cells and plasma cells), and the expression of major histocompatibility complex–related genes and chemokine-related genes in BRCA. …”
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101485por Mpagama, Stellah G., Mvungi, Happiness C., Mbelele, Peter M., Semvua, Hadija H., Liyoyo, Alphonce A., de Guex, Kristen Petros, Sloan, Derek, Kibiki, Gibson S., Boeree, Martin, Phillips, Patrick P. J., Heysell, Scott K.“…ADR monitoring will be performed at baseline and daily follow-up over 24 weeks including blood and urine specimen collection for hepatic and renal function and electrolyte abnormalities, and electrocardiogram. …”
Publicado 2023
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101486por Wang, Jen-Yeu, Qu, Vera, Hui, Caressa, Sandhu, Navjot, Mendoza, Maria G., Panjwani, Neil, Chang, Yu-Cheng, Liang, Chih-Hung, Lu, Jen-Tang, Wang, Lei, Kovalchuk, Nataliya, Gensheimer, Michael F., Soltys, Scott G., Pollom, Erqi L.“…The primary site breakdown was 56% lung, 10% melanoma, 9% breast, 8% gynecological, 5% renal, 4% gastrointestinal, 2% sarcoma, and 6% other, while the race breakdown was 60% White, 18% Asian, 3% Black/African American, 2% Native Hawaiian or other Pacific Islander, and 17% other/unknown/not reported. …”
Publicado 2023
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101487por Chang, Pei-Chi, Lin, Yu-Chieh, Yen, Hui-Ju, Hueng, Dueng-Yuan, Huang, Shih-Ming, Li, Yao-Feng“…It has recently been described as a prognostic marker in renal tumors. Here, we aim to use sophisticated bioinformatics and experimental validation to characterize the AUP1's role in glioma. …”
Publicado 2023
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101488por Burns, Katherine, Malik, Bobby, Villasmil, Ricardo, Walo, Richard, Whiteside, Zachary, Baez-Rodriguez, Karla, Wiese-Rometsch, Wilhelmine“…There were no intergroup differences with most prevalent comorbidities at admission including hypertension (99%), diabetes (41%), chronic pulmonary disease (37%), obesity (36%), deficiency anemia (31%), and renal failure (25%). There were no intergroup differences in initiation of COVID-19 directed treatments. …”
Publicado 2023
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101489por Bramlage, Peter, Lanzinger, Stefanie, Mühldorfer, Steffen, Milek, Karsten, Gillessen, Anton, Veith, Roman, Ohde, Tobias, Danne, Thomas, Holl, Reinhard W., Seufert, Jochen“…BACKGROUND: The FIDELIO-DKD and FIGARO-DKD randomized clinical trials (RCTs) showed finerenone, a novel non-steroidal mineralocorticoid receptor antagonist (MRA), reduced the risk of renal and cardiovascular events in patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). …”
Publicado 2023
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101490por Machado, Pedro M, Schäfer, Martin, Mahil, Satveer K, Liew, Jean, Gossec, Laure, Dand, Nick, Pfeil, Alexander, Strangfeld, Anja, Regierer, Anne Constanze, Fautrel, Bruno, Alonso, Carla Gimena, Saad, Carla G S, Griffiths, Christopher E M, Lomater, Claudia, Miceli-Richard, Corinne, Wendling, Daniel, Alpizar Rodriguez, Deshire, Wiek, Dieter, Mateus, Elsa F, Sirotich, Emily, Soriano, Enrique R, Ribeiro, Francinne Machado, Omura, Felipe, Rajão Martins, Frederico, Santos, Helena, Dau, Jonathan, Barker, Jonathan N, Hausmann, Jonathan, Hyrich, Kimme L, Gensler, Lianne, Silva, Ligia, Jacobsohn, Lindsay, Carmona, Loreto, Pinheiro, Marcelo M, Zelaya, Marcos David, Severina, María de los Ángeles, Yates, Mark, Dubreuil, Maureen, Gore-Massy, Monique, Romeo, Nicoletta, Haroon, Nigil, Sufka, Paul, Grainger, Rebecca, Hasseli, Rebecca, Lawson-Tovey, Saskia, Bhana, Suleman, Pham, Thao, Olofsson, Tor, Bautista-Molano, Wilson, Wallace, Zachary S, Yiu, Zenas Z N, Yazdany, Jinoos, Robinson, Philip C, Smith, Catherine H“…Male sex (OR 1.54, 95% CI 1.30 to 1.83), cardiovascular, respiratory, renal, metabolic and cancer comorbidities (ORs 1.25–2.89), moderate/high disease activity and/or glucocorticoid use (ORs 1.39–2.23, vs remission/low disease activity and no glucocorticoids) were associated with increased odds of severe COVID-19. …”
Publicado 2023
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101491por Liang, Jinxiu, Hao, Wenke, Xia, Fangxiao, Zhao, Zhi, Wu, Yanhua, Yu, Feng, Hu, Wenxue, Fang, Xiaowu, Liu, Wei“…Overall, 44 patients, accounting for 65.7%, achieved remission including complete remission and partial remission within 1 year after renal biopsy. Compared with a non-remission group, the levels of uPCR (6274.6 vs. 3235.6 mg/g, p = 0.007) and uACR (3433.6 vs. 1773.2 mg/g, p = 0.017) were significantly higher in remission group. …”
Publicado 2023
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101492por Sabouret, S P F, Leclercq, L C, Tamberou, C T, Cortinovis, C L, Moniot, M A, Deharo, D J C“…Patients included had visited their GP in 2019 and were followed for ≥ 3 years, were aged ≥ 50 with ≥ 1 risk markers potentially associated with AF (HTN, diabetes, obesity, dyslipidaemia, smoking, alcohol dependence, cardiopathy, heart failure (HF), vascular disease, OSA, chronic obstructive pulmonary disease, inflammatory disease, thyroid or renal dysfunction). Non-AF patients with anticoagulant treatment were excluded. …”
Publicado 2023
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101493por Rocchetti, Maria Teresa, Pesce, Francesco, Matino, Silvia, Piscopo, Giovanni, di Bari, Ighli, Trepiccione, Francesco, Capolongo, Giovanna, Perniola, Maria Antonietta, Song, Xuewen, Khowaja, Saima, Haghighi, Amirreza, Peters, Dorien, Paolicelli, Simona, Pontrelli, Paola, Netti, Giuseppe Stefano, Ranieri, Elena, Capasso, Giovambattista, Moschetta, Marco, Pei, York, Gesualdo, Loreto“…Further, the ratio of urinary epidermal growth factor and monocyte chemotactic peptide 1 at baseline showed a positive correlation (p = 0.006, r = 0.36) with renal outcome (delta-estimated glomerular filtration rate per year, over a mean follow-up of 4.2 ± 1.2 years). …”
Publicado 2022
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101494por Ochoa-Gondar, Olga, Torras-Vives, Verónica, de Diego-Cabanes, Cinta, Satué-Gracia, Eva M., Vila-Rovira, Angel, Forcadell-Perisa, María J., Ribas-Seguí, Domingo, Rodríguez-Casado, Clara, Vila-Córcoles, Angel“…Maximum IRs emerged among persons with history of previous IPD or all-cause pneumonia, followed by haematological neoplasia (475.0), HIV-infection (423.7), renal disease (384.9), chronic respiratory disease (314.7), liver disease (232.5), heart disease (221.4), alcoholism (204.8), solid cancer (186.2) and diabetes (159.6). …”
Publicado 2023
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101495por Fisher, Louis, Hopcroft, Lisa EM, Rodgers, Sarah, Barrett, James, Oliver, Kerry, Avery, Anthony J, Evans, Dai, Curtis, Helen, Croker, Richard, Macdonald, Orla, Morley, Jessica, Mehrkar, Amir, Bacon, Sebastian, Davy, Simon, Dillingham, Iain, Evans, David, Hickman, George, Inglesby, Peter, Morton, Caroline E, Smith, Becky, Ward, Tom, Hulme, William, Green, Amelia, Massey, Jon, Walker, Alex J, Bates, Christopher, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, O’Hanlon, Shaun, Eavis, Alex, Jarvis, Richard, Avramov, Dima, Griffiths, Paul, Fowles, Aaron, Parkes, Nasreen, Goldacre, Ben, MacKenna, Brian“…Prescriptions that do not adhere to these indicators are potentially hazardous and can cause gastrointestinal bleeds; are cautioned against in specific conditions (specifically heart failure, asthma, and chronic renal failure); or require blood test monitoring. …”
Publicado 2023
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101496por Wundram, Steffen, Seoudy, Hatim, Dümmler, Johannes C., Ritter, Lukas, Frank, Johanne, Puehler, Thomas, Lutter, Georg, Lutz, Matthias, Saad, Mohammed, Bramlage, Peter, Sathananthan, Janarthanan, Wood, David A., Lauck, Sandra B., Frey, Norbert, Frank, Derk“…Factors associated with a failure of achieving a total length of stay of ≤ 5 days comprised frailty syndrome, renal impairment as well as new permanent pacemaker implantation, new bundle branch block or atrial fibrillation, life-threatening bleeding, and the use of self-expanding valves. …”
Publicado 2023
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101497por Lewis, Francesca, Oakley, Robert, Hatch, Jennifer, Elst, Zoë Vander, Smits, Anne, Duffy, Donovan“…Neonatal pharmacokinetic (PK) variability due to evolving renal function/distribution volume/non-blood protein-bound vancomycin concentrations, likely contributed to non-therapeutic concentrations. …”
Publicado 2023
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101498por Gundogmus, Ayse Gokcen, Oguz, Ebru Gok, Guler-Cimen, Sanem, Kocyigit, Yasemin, Dogan, Ahmet Emin, Ayli, Mehmet Deniz“…BACKGROUND: Kidney transplantation (KT) and end-stage renal disease (ESRD) requiring hemodialysis (HD) increase the incidence of morbidity and mortality associated with coronavirus disease 2019 (COVID-19) infection. …”
Publicado 2023
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101499“…Similarly, in the meta-analysis, SGLT-2i therapy tended to be more effective in reducing 3P-MACE in people with eGFR < 60 ml/min/1.73 m(2) than in those with normal renal function (ARR − 0.90 [–1.44 to − 0.37] vs. − 0.17 [–0.34 to − 0.01] events/100 person-years). …”
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101500“…More significant correlations between symptoms improvements and ΔT changes were observed in Group A, and its ΔT changes in Upper Jiao, Shenque (CV8), Zhongwan (CV12), Danzhong (CV17), Zhiyang (GV9), Dazhui (GV14), upper arm, thoracic segments, lumbar segments, renal region, popliteal fossa strongly correlated with the improvement of Spleen-Kidney Yang Deficiency symptoms. …”
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