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  1. 101741
    “…BMD modeling with model averaging for renal cancer studies (Kurokawa et al., J Natl. Cancer Inst, 1983 and 1986a; DeAngelo et al., Toxicol Pathol 26:587–594, 1998) resulted in a median hBMDL(10) of 0.65 mg bromate/kg body weight (bw) per day. …”
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    New aspects in deriving health-based guidance values for bromate in swimming pool water
  2. 101742
    “…The maximum SMA diameter was 12.1 (11.3–13.1) mm, and the maximum SMA diameter was located on the left renal vein (LRV) plane in 68.2% of cases. Dissection features observed on contrast-enhanced CT (CECT), CT angiography (CTA), or digital subtraction angiography (DSA) showed that there were 70 cases (63.6%) of Yun type IIb SISMAD, the maximum SMA diameter was 13.0 ± 2.4 mm, the location of the maximum SMA diameter was on the LRV plane in 64.5% of cases, and 7.3% of cases were complicated with intestinal obstruction, including bowel necrosis in 3.6% of cases. …”
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    Clinical characteristics and misdiagnosis of spontaneous isolated superior mesenteric artery dissection
  3. 101743
    “…Ambulatory 24-h blood pressure and central hemodynamic parameters were evaluated. Data on renal function and diabetic kidney disease was retrieved. …”
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    Arterial stiffness in patients with type 1 diabetes and its comparison to cardiovascular risk evaluation tools
  4. 101744
    “…RESULTS: In HVs, cemdisiran was rapidly converted to a major active metabolite, AS(N-2)3′-cemdisiran, both declining below the lower limit of quantification (LLOQ) in plasma within 48 h, and showing minimal renal excretion. AS(N-2)3′-cemdisiran exhibited more than dose-proportional PK. …”
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    Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria
  5. 101745
    “…Follow-up data will be collected by linkage to routine healthcare databases — Hospital Episode Statistics, Civil Registration, Public Health England and the UK Renal Registry (UKRR) in England, and equivalent databases in Scotland and Wales, as necessary — and centrally administered patient-completed questionnaires. …”
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    The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to compare the effectiveness and cost-effectiveness of high-volume haemodiafiltration and high-flux haemodialysis in people with kidney failure on maintenance dialysis using linkage to routine healthcare databases for outcomes
  6. 101746
    “…Additional factors associated with survival were younger age, shorter time between intubation and ECMO initiation, BMI > 35 (compared to < 25), absence of renal replacement therapy or major bleeding/thromboembolic events. …”
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    Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation
  7. 101747
    “…A total of 402 689 patients 20 years or older who were diagnosed with stage IV non–small cell lung cancer (NSCLC), renal cell carcinoma (RCC), or melanoma of the skin between January 1, 2007, and December 31, 2018 (specific years varied by tumor type), were included. …”
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    Association Between Food and Drug Administration Approval and Disparities in Immunotherapy Use Among Patients With Cancer in the US
  8. 101748
    por Schillemans, Tessa, Tragante, Vinicius, Maitusong, Buamina, Gigante, Bruna, Cresci, Sharon, Laguzzi, Federica, Vikström, Max, Richards, Mark, Pilbrow, Anna, Cameron, Vicky, Foco, Luisa, Doughty, Robert N., Kuukasjärvi, Pekka, Allayee, Hooman, Hartiala, Jaana A., Tang, W. H. Wilson, Lyytikäinen, Leo-Pekka, Nikus, Kjell, Laurikka, Jari O., Srinivasan, Sundararajan, Mordi, Ify R., Trompet, Stella, Kraaijeveld, Adriaan, van Setten, Jessica, Gijsberts, Crystel M., Maitland-van der Zee, Anke H., Saely, Christoph H., Gong, Yan, Johnson, Julie A., Cooper-DeHoff, Rhonda M., Pepine, Carl J., Casu, Gavino, Leiherer, Andreas, Drexel, Heinz, Horne, Benjamin D., van der Laan, Sander W., Marziliano, Nicola, Hazen, Stanley L., Sinisalo, Juha, Kähönen, Mika, Lehtimäki, Terho, Lang, Chim C., Burkhardt, Ralph, Scholz, Markus, Jukema, J. Wouter, Eriksson, Niclas, Åkerblom, Axel, James, Stefan, Held, Claes, Hagström, Emil, Spertus, John A., Algra, Ale, de Faire, Ulf, Åkesson, Agneta, Asselbergs, Folkert W., Patel, Riyaz S., Leander, Karin
    Publicado 2022
    “…The results from stratified analyses showed null results, except for significant inverse associations between rs7672915 (intron 2) and the primary outcome among 1) individuals aged ≥65, 2) individuals with renal impairment, and 3) antiplatelet users. Conclusion: We found no clear associations between polymorphisms in the PPARGC1A gene and subsequent CHD events in patients with established CHD at baseline.…”
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    Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis
  9. 101749
    “…Pre-operative stone information included the size (mm), Hounsfield units (HU), laterality and intra-renal anatomical location. Peri-operative surgical details included surgical time in minutes; Laser use; Duration and energy of laser; and post-operative stenting. …”
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    Pre- and peri-operative clinical information, physiological observations and outcome measures following flexible ureterorenoscopy (FURS), for the treatment of kidney stones. A single-centre observational clinical pilot-study in 51 patients
  10. 101750
    “…The miR-182(−/−)B6/lpr and miR-183C(−/−)B6/lpr mice had significantly reduced deposition of IgG immunocomplexes in the kidney when compared to their respective littermate controls, although there appeared to be no remarkable changes in renal pathology. Importantly, we observed a significant reduction of serum anti-dsDNA autoantibodies in miR-183C(−/−)B6/lpr mice after reaching 24 weeks-of age compared to age-matched miR-183C(fl/fl)B6/lpr controls. …”
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    Deletion of microRNA-183-96-182 Cluster in Lymphocytes Suppresses Anti-DsDNA Autoantibody Production and IgG Deposition in the Kidneys in C57BL/6-Fas(lpr/lpr) Mice
  11. 101751
    “…Also, among the comorbidities, the main predictors were the presence of immunosuppressive disorder (OR = 1.44; 95% CI = 1.39-1.49), neurological disorder (OR = 1.21; 95% CI = 1.17-1.25), hepatic disorder (OR = 1.41; 95% CI = 1.34-1.50), diabetes mellitus (OR = 1.40; 95% CI = 1.37-1.42), cardiopathy (OR = 1.13; 95%CI = 1.11-1.14), hematologic disorder (OR = 1.34; 95% CI = 1.24-1.43), Down syndrome (OR = 1.61; 95% CI = 1.43-1.81), renal disease (OR = 1.15; 95% CI = 1.11-1.18), and obesity (OR = 1.18; 95% CI = 1.15-1.21). …”
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    Characterization of demographic data, clinical signs, comorbidities, and outcomes according to the race in hospitalized individuals with COVID-19 in Brazil: An observational study
  12. 101752
    “…The sample size of these 6 studies was 12,534, and the kidney disease types could be divided into chronic kidney disease (CKD) and Immunoglobulin A Nephropathy, with 5 articles using end-stage renal diseases occurrence as the primary outcome. …”
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    Machine learning algorithms’ accuracy in predicting kidney disease progression: a systematic review and meta-analysis
  13. 101753
    “…Booster vaccination could prevent HZ. However, end-stage renal disease (ESRD) patients show poor immunological responses to vaccinations. …”
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    Boosting the VZV-Specific Memory B and T Cell Response to Prevent Herpes Zoster After Kidney Transplantation
  14. 101754
    “…When comparing the infant group (N=27) and the older age group (≥ 1 year, N=221), there were no difference in hematological toxicities, however, non-hematological toxicities, such as renal, cardiac, pulmonary, neurological complications, and tumor lysis syndrome were significantly more common in the infant group. …”
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    Unexpected High Mortality Rate Due to Acute Respiratory Distress Syndrome Among Infants with AML Enrolled on JPLSG AML-05 Trial
  15. 101755
    por Valle-Hita, Cristina, Díaz-López, Andrés, Becerra-Tomás, Nerea, Martínez-González, Miguel A., García, Verónica Ruiz, Corella, Dolores, Goday, Albert, Martínez, J. Alfredo, Alonso-Gómez, Ángel M., Wärnberg, Julia, Vioque, Jesús, Romaguera, Dora, López-Miranda, José, Estruch, Ramon, Tinahones, Francisco J., Lapetra, José, Serra-Majem, Luís, Cano-Ibáñez, Naomi, Tur, Josep A., Rubín-García, María, Pintó, Xavier, Delgado-Rodríguez, Miguel, Matía-Martín, Pilar, Vidal, Josep, Fontao, Sebastian Mas, Daimiel, Lidia, Ros, Emilio, Toledo, Estefania, Sorlí, José V., Roca, C., Abete, Iztiar, Moreno-Rodriguez, Anai, Crespo-Oliva, Edelys, Candela-García, Inmaculada, Morey, Marga, Garcia-Rios, Antonio, Casas, Rosa, Fernandez-Garcia, Jose Carlos, Santos-Lozano, José Manuel, Diez-Espino, Javier, Ortega-Azorín, Carolina, Comas, M., Zulet, M. Angeles, Sorto-Sanchez, Carolina, Ruiz-Canela, Miguel, Fitó, Montse, Salas-Salvadó, Jordi, Babio, Nancy
    Publicado 2022
    “…RESULTS: Participants in the highest tertile of increase in 17-item erMedDiet Score showed higher upward changes in eGFR (β: 1.87 ml/min/1.73m(2); 95% CI: 1.00–2.73) and had lower odds of ≥ 10% eGFR decline (OR: 0.62; 95% CI: 0.47–0.82) compared to individuals in the decrease/maintenance category, while Trichopoulou-MedDiet and DASH Scores were not associated with any renal outcomes. Those in the highest tertile of increase in Protein Diet Score had greater downward changes in eGFR (β: − 0.87 ml/min/1.73m(2); 95% CI: − 1.73 to − 0.01) and 32% higher odds of eGFR decline (OR: 1.32; 95% CI: 1.00–1.75). …”
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    Prospective associations between a priori dietary patterns adherence and kidney function in an elderly Mediterranean population at high cardiovascular risk
  16. 101756
    “…Decreased serum TG levels are treated by non-invasive methods, which include anti-lipidemic agents, heparin, low-molecular weight heparin, and insulin, and invasive methods, such as blood purification including hemoperfusion (HP), plasmapheresis, and continuous renal replacement therapy. However, authoritative guidelines have not been established. …”
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    Incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis: A retrospective single-center study
  17. 101757
    “…There were no significant differences in ORR [RR = 1.32, 95% CI (0.94~1.86)] and DCR [RR = 1.22, 95% CI (0.99~1.50)], but they can improve the KPS response rate [RR = 1.62, 95% CI (1.13, 2.32)] and decrease the incidence of myelosuppression, nausea and vomiting, diarrhea, and hepatic and renal dysfunction in CRC. CONCLUSION: This study indicates that herbal formulas that could regulate the composition and proportion of gut microbiota have a positive effect in three stages (perioperative, postoperative, and advanced) of GC and CRC. …”
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    Efficacy and safety of herbal formulas with the function of gut microbiota regulation for gastric and colorectal cancer: A systematic review and meta-analysis
  18. 101758
    “…The groups were well-matched for baseline characteristics (age, diabetes duration, HbA1c, renal and heart function). There was no significant change in MGU during euglycemic hyperinsulinemic clamp in the dapagliflozin group (2.22 ± 0.59 vs 1.92 ± 0.42 μmol/100 g/min, p = 0.41) compared with the placebo group (2.00 ± 0.55 vs 1.60 ± 0.45 μmol/100 g/min, p = 0.5). …”
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    Dapagliflozin improves myocardial flow reserve in patients with type 2 diabetes: the DAPAHEART Trial: a preliminary report
  19. 101759
    “…Aos exames, apresentava anemia, linfopenia, plaquetopenia e neutrofilia, presença de esquizófitos, além de provas inflamatórias alteradas, alargamento de INR, hipoalbuminemia e hiperbilirrubinemia, injuria renal aguda sem hipercalemia e sem dismorfismo eritrocitário, consumo de complemento, haptoglobina reduzida, coombs direto negativo e hemoculturas negativas. …”
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    RELATO DE CASO DE LEPTOSPIROSE COM ACHADO DE SARS-COV-2 EM IMUNO-HISTOQUÍMICA
  20. 101760
    “…Quanto as comorbidades, 29,0% faziam uso de álcool, 21,0% de drogas, 21,0% tinham doença renal, 7,0% HIV, 7,0% diabetes. Em relação ao desfecho dos casos durante a internação, 9 (64%) casos receberam alta hospitalar e 5 (36,0%) foram a óbito. …”
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    COINFECÇÃO TUBERCULOSE E COVID-19
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