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  1. 102141
    “…Une masse tissulaire surrénalienne droite a été retrouvée sur une échographie rénale de routine et confirmée par un scanner scanner abdominal. …”
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    Syndrome coronaire aigu: un mode de révélation peu fréquent du phéochromocytome
  2. 102142
    “…Les facteurs de risque surajoutés sont représentés par la présence des anticorps antiphospholipides (47% des cas), la néphropathie lupique (49% des cas), l'insuffisance rénale (42% des cas), la corticothérapie au long cours (74% des cas) et la chronicité de la maladie dans 35% des cas. …”
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    Facteurs de risque cardiovasculaires au cours du lupus systémique
  3. 102143
    “…A population pharmacokinetic (PPK) model was constructed using nonparametric estimation to compare the pharmacokinetic (PK) behaviors of isavuconazole in patients treated in the phase 3 VITAL open-label clinical trial, which evaluated the efficacy and safety of the drug for treatment of renally impaired IA patients and patients with invasive fungal disease (IFD) caused by emerging molds, yeasts, and dimorphic fungi. …”
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    Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)
  4. 102144
    “…AIMS: Metformin is renally excreted and has been associated with the development of lactic acidosis. …”
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    Acute kidney injury, plasma lactate concentrations and lactic acidosis in metformin users: A GoDarts study
  5. 102145
    “…BACKGROUND: Chronic kidney disease (CKD) alters the pharmacokinetic and pharmacodynamic responses of various renally excreted drugs and increases the risk of drug-related problems, such as drug–drug interactions. …”
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    Clinical relevancy and determinants of potential drug–drug interactions in chronic kidney disease patients: results from a retrospective analysis
  6. 102146
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    The effectiveness of disinfectant and steam exposure treatments to prevent the spread of the highly invasive killer shrimp, Dikerogammarus villosus
  7. 102147
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    Association between SNPs and Loss of Methylation Site on the CpG island of the Promoter Region of the Smoothened Gene, Potential Molecular Markers for Susceptibility to the Development of Basal Cell Carcinoma in the Brazilian Population
  8. 102148
    “…Simulated steady-state concentrations were 1.43-times, 95%CI = (1.27; 1.61), higher in plasma versus target-site, supporting targets of %fT(>2×MIC) instead of %fT(>4×MIC) during continuous infusion to avoid target-site concentrations constantly below MIC. In all obesity and renally impairment/hyperfiltration stages, at MIC = 16 mg/L, adequate PTA required prolonged (thrice-daily 4 g/0.5 g over 3.0 h at %fT(>MIC) = 50) or continuous infusions (24 g/3 g over 24 h following loading dose at %fT(>MIC) = 98) of piperacillin/tazobactam.…”
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    Similar Piperacillin/Tazobactam Target Attainment in Obese versus Nonobese Patients despite Differences in Interstitial Tissue Fluid Pharmacokinetics
  9. 102149
    “…As a small hydrophilic peptide-based drug BT8009 rapidly diffuses from the systemic circulation, through tissues to penetrate the tumor and target tumor cells. It is renally eliminated from the circulation, with a half-life of 1–2 hours in rat and non-human primate. …”
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    BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
  10. 102150
    “…It is primarily eliminated renally and may induce acute kidney injury (AKI) at a rate of up to 53%. …”
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    Colistin Loading Dose in Septic Patients with Gram Negative Infections
  11. 102151
    “…METHODS: Data were pooled from three Phase I, randomized, double‐blind idarucizumab studies in healthy Caucasian subjects; elderly, renally impaired subjects; and healthy Japanese subjects. …”
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    Evaluation of the immunogenicity of the dabigatran reversal agent idarucizumab during Phase I studies
  12. 102152
    “…CONCLUSIONS: Transmission electron microscopy analysis of cerebellums of renally impaired rats repeatedly injected with gadobenate and gadodiamide revealed the presence of Gd. …”
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    Multimodal Imaging Study of Gadolinium Presence in Rat Cerebellum: Differences Between Gd Chelates, Presence in the Virchow-Robin Space, Association With Lipofuscin, and Hypotheses About Distribution Pathway
  13. 102153
    “…OBJECTIVE: Upacicalcet is a new renally excreted and injectable calcimimetic agent. …”
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    First-in-Patient Phase I/II Study of Upacicalcet in Japanese Patients with Secondary Hyperparathyroidism Undergoing Hemodialysis: Pharmacokinetic and Pharmacodynamic Properties
  14. 102154
    por Heudorf, U, Angerer, J
    Publicado 2001
    “…In humans, they are rapidly metabolized and renally eliminated. In numerous studies, pyrethroid metabolites have been detected in urine after occupational exposure to insecticides. …”
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    Metabolites of pyrethroid insecticides in urine specimens: current exposure in an urban population in Germany.
  15. 102155
    “…L'augmentation de l'incidence de la maladie rénale chronique, du diabète et l'amélioration de la survie cardio-vasculaire expliquent en grande partie ce constat. …”
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    Le sujet âgé en hémodialyse chronique: expérience d'un centre hospitalier marocain
  16. 102156
    “…L'analyse des facteurs de risque de mortalité par hémorragie en milieu de réanimation a montré une association statistiquement significative entre la survenue du décès et les facteurs suivants: recours aux catécholamines, survenue de sepsis, œdème pulmonaire aigu, coagulation intravasculaire disséminée, insuffisance rénale aigue avec recours à l'hémodialyse, SDRA ou TRALI, atteinte neurologique grave, défaillance multiviscérale et arrêt cardiaque récupéré.…”
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    L'hemorragie grave du peripartum en milieu de reanimation dans un centre universitaire tunisien de niveau 3: épidémiologie et facteurs de risque de mortalité maternelle
  17. 102157
    “…Reductions in the cost of treating recurrence with fidaxomicin ranged from −€574.32 per patient in those receiving concomitant antibiotics to −€1500.68 per patient in renally impaired patients. CONCLUSIONS: In patient subgroups with CDI at increased recurrence risk, fidaxomicin was cost-effective vs. vancomycin, and less costly and more effective in patients with cancer. …”
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    A cost-effectiveness and budget impact analysis of first-line fidaxomicin for patients with Clostridium difficile infection (CDI) in Germany
  18. 102158
    “…This suggests that a high proportion of the recommended salt doses is excreted renally. The above effects of NaCl supplementation persisted over the 2 week measurement period. …”
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    Effects of Different Oral Doses of Sodium Chloride on the Basal Acid-Base and Mineral Status of Exercising Horses Fed Low Amounts of Hay
  19. 102159
    “…Les associations les plus fortes étaient retrouvées pour la transplantation rénale (HRa 32 [28-37] et 34 [24-47]), la transplantation du poumon (HRa 14 [8,1-23] et 11 [1,5-88]), l'insuffisance rénale en dialyse (HRa 7,0 [5,9-8,2] et HRa 8,6 [6,3-12]), la trisomie 21 (HRa 3,9 [2,1- 7,3] et 45 [16-127]), le retard mental (HRa 3,6 [2,5-5,0] et 3,1 [1,0-10]) et le cancer actif du poumon (HRa 3,5 [2,7-4,4] et 6,5 [4,2-10]). …”
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    Caractéristiques sociodémographiques et médicales associées au risque d’échec d'un schéma vaccinal deux doses contre la COVID-19 en France
  20. 102160
    “…RESULTS: [(68)Ga]Ga-CDI is safe and well-tolerated with no side effects or adverse events. [(68)Ga]Ga-CDI is renally excreted, demonstrates low levels of physiologic uptake in the other organs and has excellent imaging characteristics. …”
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    A first-in-human study of [(68)Ga]Ga-CDI: a positron emitting radiopharmaceutical for imaging tumour cell death
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