Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function

por Tang, Wenbo, Kowgier, Matthew, Loth, Daan W., Soler Artigas, María, Joubert, Bonnie R., Hodge, Emily, Gharib, Sina A., Smith, Albert V., Ruczinski, Ingo, Gudnason, Vilmundur, Mathias, Rasika A., Harris, Tamara B., Hansel, Nadia N., Launer, Lenore J., Barnes, Kathleen C., Hansen, Joyanna G., Albrecht, Eva, Aldrich, Melinda C., Allerhand, Michael, Barr, R. Graham, Brusselle, Guy G., Couper, David J., Curjuric, Ivan, Davies, Gail, Deary, Ian J., Dupuis, Josée, Fall, Tove, Foy, Millennia, Franceschini, Nora, Gao, Wei, Gläser, Sven, Gu, Xiangjun, Hancock, Dana B., Heinrich, Joachim, Hofman, Albert, Imboden, Medea, Ingelsson, Erik, James, Alan, Karrasch, Stefan, Koch, Beate, Kritchevsky, Stephen B., Kumar, Ashish, Lahousse, Lies, Li, Guo, Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Lohman, Kurt, Lumley, Thomas, McArdle, Wendy L., Meibohm, Bernd, Morris, Andrew P., Morrison, Alanna C., Musk, Bill, North, Kari E., Palmer, Lyle J., Probst-Hensch, Nicole M., Psaty, Bruce M., Rivadeneira, Fernando, Rotter, Jerome I., Schulz, Holger, Smith, Lewis J., Sood, Akshay, Starr, John M., Strachan, David P., Teumer, Alexander, Uitterlinden, André G., Völzke, Henry, Voorman, Arend, Wain, Louise V., Wells, Martin T., Wilk, Jemma B., Williams, O. Dale, Heckbert, Susan R., Stricker, Bruno H., London, Stephanie J., Fornage, Myriam, Tobin, Martin D., O′Connor, George T., Hall, Ian P., Cassano, Patricia A.
Publicado 2014

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

por Li, Jingmei, Lindström, Linda S., Foo, Jia N., Rafiq, Sajjad, Schmidt, Marjanka K., Pharoah, Paul D. P., Michailidou, Kyriaki, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Van ‘t Veer, Laura J., Cornelissen, Sten, Rutgers, Emiel, Southey, Melissa C., Apicella, Carmel, Dite, Gillian S., Hopper, John L., Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B., Beckmann, Matthias W., Blomqvist, Carl, Muranen, Taru A., Aittomäki, Kristiina, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kosma, Veli-Matti, Hartikainen, Jaana M., Kataja, Vesa, Chenevix-Trench, Georgia, Investigators, kConFab, Phillips, Kelly-Anne, McLachlan, Sue-Anne, Lambrechts, Diether, Thienpont, Bernard, Smeets, Ann, Wildiers, Hans, Chang-Claude, Jenny, Flesch-Janys, Dieter, Seibold, Petra, Rudolph, Anja, Giles, Graham G., Baglietto, Laura, Severi, Gianluca, Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Kristensen, Vessela, Alnæs, Grethe I. Grenaker, Borresen-Dale, Anne-Lise, Nord, Silje, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Devilee, Peter, Tollenaar, Robert, Seynaeve, Caroline, Hooning, Maartje, Kriege, Mieke, Hollestelle, Antoinette, van den Ouweland, Ans, Li, Yi, Hamann, Ute, Torres, Diana, Ulmer, Hans U., Rüdiger, Thomas, Shen, Chen-Yang, Hsiung, Chia-Ni, Wu, Pei-Ei, Chen, Shou-Tung, Teo, Soo Hwang, Taib, Nur Aishah Mohd, Har Yip, Cheng, Fuang Ho, Gwo, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K., Yoo, Keun-Young, Maishman, Tom, Tapper, William J., Dunning, Alison, Shah, Mitul, Luben, Robert, Brown, Judith, Chuen Khor, Chiea, Eccles, Diana M., Nevanlinna, Heli, Easton, Douglas, Humphreys, Keith, Liu, Jianjun, Hall, Per, Czene, Kamila
Publicado 2014

Association between Class III Obesity (BMI of 40–59 kg/m(2)) and Mortality: A Pooled Analysis of 20 Prospective Studies

por Kitahara, Cari M., Flint, Alan J., Berrington de Gonzalez, Amy, Bernstein, Leslie, Brotzman, Michelle, MacInnis, Robert J., Moore, Steven C., Robien, Kim, Rosenberg, Philip S., Singh, Pramil N., Weiderpass, Elisabete, Adami, Hans Olov, Anton-Culver, Hoda, Ballard-Barbash, Rachel, Buring, Julie E., Freedman, D. Michal, Fraser, Gary E., Beane Freeman, Laura E., Gapstur, Susan M., Gaziano, John Michael, Giles, Graham G., Håkansson, Niclas, Hoppin, Jane A., Hu, Frank B., Koenig, Karen, Linet, Martha S., Park, Yikyung, Patel, Alpa V., Purdue, Mark P., Schairer, Catherine, Sesso, Howard D., Visvanathan, Kala, White, Emily, Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Hartge, Patricia
Publicado 2014

FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

por Asad, M, Wong, M K, Tan, T Z, Choolani, M, Low, J, Mori, S, Virshup, D, Thiery, J P, Huang, R Y-J
Publicado 2014

Gastric ulcer patients are more susceptible to developing gastric cancer compared with concomitant gastric and duodenal ulcer patients

por HONG, JUN-BO, ZUO, WEI, WANG, AN-JIANG, XU, SHAN, TU, LU-XIA, CHEN, YOU-XIANG, ZHU, XUAN, LU, NONG-HUA
Publicado 2014

Sublingual Misoprostol versus Intramuscular Oxytocin for Prevention of Postpartum Hemorrhage in Uganda: A Double-Blind Randomized Non-Inferiority Trial

por Atukunda, Esther C., Siedner, Mark J., Obua, Celestino, Mugyenyi, Godfrey R., Twagirumukiza, Marc, Agaba, Amon G.
Publicado 2014

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

por Galluzzi, L, Bravo-San Pedro, J M, Vitale, I, Aaronson, S A, Abrams, J M, Adam, D, Alnemri, E S, Altucci, L, Andrews, D, Annicchiarico-Petruzzelli, M, Baehrecke, E H, Bazan, N G, Bertrand, M J, Bianchi, K, Blagosklonny, M V, Blomgren, K, Borner, C, Bredesen, D E, Brenner, C, Campanella, M, Candi, E, Cecconi, F, Chan, F K, Chandel, N S, Cheng, E H, Chipuk, J E, Cidlowski, J A, Ciechanover, A, Dawson, T M, Dawson, V L, De Laurenzi, V, De Maria, R, Debatin, K-M, Di Daniele, N, Dixit, V M, Dynlacht, B D, El-Deiry, W S, Fimia, G M, Flavell, R A, Fulda, S, Garrido, C, Gougeon, M-L, Green, D R, Gronemeyer, H, Hajnoczky, G, Hardwick, J M, Hengartner, M O, Ichijo, H, Joseph, B, Jost, P J, Kaufmann, T, Kepp, O, Klionsky, D J, Knight, R A, Kumar, S, Lemasters, J J, Levine, B, Linkermann, A, Lipton, S A, Lockshin, R A, López-Otín, C, Lugli, E, Madeo, F, Malorni, W, Marine, J-C, Martin, S J, Martinou, J-C, Medema, J P, Meier, P, Melino, S, Mizushima, N, Moll, U, Muñoz-Pinedo, C, Nuñez, G, Oberst, A, Panaretakis, T, Penninger, J M, Peter, M E, Piacentini, M, Pinton, P, Prehn, J H, Puthalakath, H, Rabinovich, G A, Ravichandran, K S, Rizzuto, R, Rodrigues, C M, Rubinsztein, D C, Rudel, T, Shi, Y, Simon, H-U, Stockwell, B R, Szabadkai, G, Tait, S W, Tang, H L, Tavernarakis, N, Tsujimoto, Y, Vanden Berghe, T, Vandenabeele, P, Villunger, A, Wagner, E F, Walczak, H, White, E, Wood, W G, Yuan, J, Zakeri, Z, Zhivotovsky, B, Melino, G, Kroemer, G
Publicado 2015

A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of susta...

por Bian, Yuzhu, Chang, Thomas Ming Swi
Publicado 2015

Full-Length Human Placental sFlt-1-e15a Isoform Induces Distinct Maternal Phenotypes of Preeclampsia in Mice

por Szalai, Gabor, Romero, Roberto, Chaiworapongsa, Tinnakorn, Xu, Yi, Wang, Bing, Ahn, Hyunyoung, Xu, Zhonghui, Chiang, Po Jen, Sundell, Birgitta, Wang, Rona, Jiang, Yang, Plazyo, Olesya, Olive, Mary, Tarca, Adi L., Dong, Zhong, Qureshi, Faisal, Papp, Zoltan, Hassan, Sonia S., Hernandez-Andrade, Edgar, Than, Nandor Gabor
Publicado 2015

Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells

por WANG, JIN-HANG, ZHOU, WEN-WEN, CHENG, SHI-TONG, LIU, BO-XIN, LIU, FU-RONG, SONG, JIAN-QING
Publicado 2015

Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple Negative Breast Cancer: Optimizing the Conjugate-Light Regimen

por Nagaya, Tadanobu, Sato, Kazuhide, Harada, Toshiko, Nakamura, Yuko, Choyke, Peter L., Kobayashi, Hisataka
Publicado 2015

A GWAS Study on Liver Function Test Using eMERGE Network Participants

por Namjou, Bahram, Marsolo, Keith, Lingren, Todd, Ritchie, Marylyn D., Verma, Shefali S., Cobb, Beth L., Perry, Cassandra, Kitchner, Terrie E., Brilliant, Murray H., Peissig, Peggy L., Borthwick, Kenneth M., Williams, Marc S., Grafton, Jane, Jarvik, Gail P., Holm, Ingrid A., Harley, John B.
Publicado 2015

The Polymorphism of CYP2E1 Rsa I/Pst I Gene and Susceptibility to Respiratory System Cancer: A Systematic Review and Meta-Analysis of 34 Studies

por Xu, Li, Yang, Mingyuan, Zhao, Tiejun, Jin, Hai, Xu, Zhiyun, Li, Ming, Chen, Hezhong
Publicado 2014

The Transforming Growth Factor-β1 (TGF-β1) Gene Polymorphisms (TGF-β1 T869C and TGF-β1 T29C) and Susceptibility to Postmenopausal Osteoporosis: A Meta-Analysis

por Sun, Jiajia, Zhang, Chi, Xu, Lei, Yang, Mingyuan, Yang, Huilin
Publicado 2015

Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compl...

por Oussalah, Abderrahim, Bosco, Paolo, Anello, Guido, Spada, Rosario, Guéant-Rodriguez, Rosa-Maria, Chery, Céline, Rouyer, Pierre, Josse, Thomas, Romano, Antonino, Elia, Maurizzio, Bronowicki, Jean-Pierre, Guéant, Jean-Louis
Publicado 2015

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

por Bis, Joshua C., Sitlani, Colleen, Irvin, Ryan, Avery, Christy L., Smith, Albert Vernon, Sun, Fangui, Evans, Daniel S., Musani, Solomon K., Li, Xiaohui, Trompet, Stella, Krijthe, Bouwe P., Harris, Tamara B., Quibrera, P. Miguel, Brody, Jennifer A., Demissie, Serkalem, Davis, Barry R., Wiggins, Kerri L., Tranah, Gregory J., Lange, Leslie A., Sotoodehnia, Nona, Stott, David J., Franco, Oscar H., Launer, Lenore J., Stürmer, Til, Taylor, Kent D., Cupples, L. Adrienne, Eckfeldt, John H., Smith, Nicholas L., Liu, Yongmei, Wilson, James G., Heckbert, Susan R., Buckley, Brendan M., Ikram, M. Arfan, Boerwinkle, Eric, Chen, Yii-Der Ida, de Craen, Anton J. M., Uitterlinden, Andre G., Rotter, Jerome I., Ford, Ian, Hofman, Albert, Sattar, Naveed, Slagboom, P. Eline, Westendorp, Rudi G. J., Gudnason, Vilmundur, Vasan, Ramachandran S., Lumley, Thomas, Cummings, Steven R., Taylor, Herman A., Post, Wendy, Jukema, J. Wouter, Stricker, Bruno H., Whitsel, Eric A., Psaty, Bruce M., Arnett, Donna
Publicado 2015

The transcriptional landscape of age in human peripheral blood

por Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Tukiainen, Taru, Ramos, Yolande F., Göring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., De Jager, Philip L., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, André G., Rivadeneira, Fernando, van Rooij, Jeroen, Stolk, Lisette, Broer, Linda, Verbiest, Michael M. P. J., Jhamai, Mila, Arp, Pascal, Metspalu, Andres, Tserel, Liina, Milani, Lili, Samani, Nilesh J., Peterson, Pärt, Kasela, Silva, Codd, Veryan, Peters, Annette, Ward-Caviness, Cavin K., Herder, Christian, Waldenberger, Melanie, Roden, Michael, Singmann, Paula, Zeilinger, Sonja, Illig, Thomas, Homuth, Georg, Grabe, Hans-Jörgen, Völzke, Henry, Steil, Leif, Kocher, Thomas, Murray, Anna, Melzer, David, Yaghootkar, Hanieh, Bandinelli, Stefania, Moses, Eric K., Kent, Jack W., Curran, Joanne E., Johnson, Matthew P., Williams-Blangero, Sarah, Westra, Harm-Jan, McRae, Allan F., Smith, Jennifer A., Kardia, Sharon L. R., Hovatta, Iiris, Perola, Markus, Ripatti, Samuli, Salomaa, Veikko, Henders, Anjali K., Martin, Nicholas G., Smith, Alicia K., Mehta, Divya, Binder, Elisabeth B., Nylocks, K Maria, Kennedy, Elizabeth M., Klengel, Torsten, Ding, Jingzhong, Suchy-Dicey, Astrid M., Enquobahrie, Daniel A., Brody, Jennifer, Rotter, Jerome I., Chen, Yii-Der I., Houwing-Duistermaat, Jeanine, Kloppenburg, Margreet, Slagboom, P. Eline, Helmer, Quinta, den Hollander, Wouter, Bean, Shannon, Raj, Towfique, Bakhshi, Noman, Wang, Qiao Ping, Oyston, Lisa J., Psaty, Bruce M., Tracy, Russell P., Montgomery, Grant W., Turner, Stephen T., Blangero, John, Meulenbelt, Ingrid, Ressler, Kerry J., Yang, Jian, Franke, Lude, Kettunen, Johannes, Visscher, Peter M., Neely, G. Gregory, Korstanje, Ron, Hanson, Robert L., Prokisch, Holger, Ferrucci, Luigi, Esko, Tonu, Teumer, Alexander, van Meurs, Joyce B. J., Johnson, Andrew D.
Publicado 2015

Chronic Mild Cold Conditioning Modulates the Expression of Hypothalamic Neuropeptide and Intermediary Metabolic-Related Genes and Improves Growth Performances in Young Chicks

por Nguyen, Phuong, Greene, Elizabeth, Ishola, Peter, Huff, Geraldine, Donoghue, Annie, Bottje, Walter, Dridi, Sami
Publicado 2015

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

por Cheng, Timothy HT, Thompson, Deborah, Painter, Jodie, O’Mara, Tracy, Gorman, Maggie, Martin, Lynn, Palles, Claire, Jones, Angela, Buchanan, Daniel D., Ko Win, Aung, Hopper, John, Jenkins, Mark, Lindor, Noralane M., Newcomb, Polly A., Gallinger, Steve, Conti, David, Schumacher, Fred, Casey, Graham, Giles, Graham G, Pharoah, Paul, Peto, Julian, Cox, Angela, Swerdlow, Anthony, Couch, Fergus, Cunningham, Julie M, Goode, Ellen L, Winham, Stacey J, Lambrechts, Diether, Fasching, Peter, Burwinkel, Barbara, Brenner, Hermann, Brauch, Hiltrud, Chang-Claude, Jenny, Salvesen, Helga B., Kristensen, Vessela, Darabi, Hatef, Li, Jingmei, Liu, Tao, Lindblom, Annika, Hall, Per, de Polanco, Magdalena Echeverry, Sans, Monica, Carracedo, Angel, Castellvi-Bel, Sergi, Rojas-Martinez, Augusto, Aguiar Jnr, Samuel, Teixeira, Manuel R., Dunning, Alison M, Dennis, Joe, Otton, Geoffrey, Proietto, Tony, Holliday, Elizabeth, Attia, John, Ashton, Katie, Scott, Rodney J, McEvoy, Mark, Dowdy, Sean C, Fridley, Brooke L, Werner, Henrica MJ, Trovik, Jone, Njolstad, Tormund S, Tham, Emma, Mints, Miriam, Runnebaum, Ingo, Hillemanns, Peter, Dörk, Thilo, Amant, Frederic, Schrauwen, Stefanie, Hein, Alexander, Beckmann, Matthias W, Ekici, Arif, Czene, Kamila, Meindl, Alfons, Bolla, Manjeet K, Michailidou, Kyriaki, Tyrer, Jonathan P, Wang, Qin, Ahmed, Shahana, Healey, Catherine S, Shah, Mitul, Annibali, Daniela, Depreeuw, Jeroen, Al-Tassan, Nada A., Harris, Rebecca, Meyer, Brian F., Whiffin, Nicola, Hosking, Fay J, Kinnersley, Ben, Farrington, Susan M., Timofeeva, Maria, Tenesa, Albert, Campbell, Harry, Haile, Robert W., Hodgson, Shirley, Carvajal-Carmona, Luis, Cheadle, Jeremy P., Easton, Douglas, Dunlop, Malcolm, Houlston, Richard, Spurdle, Amanda, Tomlinson, Ian
Publicado 2015

Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats

por Cramer, C. K., Yoon, S. W., Reinsvold, M., Joo, K. M., Norris, H., Hood, R. C., Adamson, J. D., Klein, R. C., Kirsch, D. G., Oldham, M.
Publicado 2015