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641“…Due to a distinct nature of thermomechanical smart materials' reaction to applied loads, a revolutionary approach is needed to measure the hardness and to understand its size effect for pseudoelastic NiTi shape memory alloys (SMAs) during the solid-state phase transition. …”
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642“…In this article, we survey the status of antibody gene transfer, review the revolutionary progress on isolation of extremely bnAbs, detail VIP experiments against HIV and its related virus conduced in humanized mice and macaque monkeys, and discuss the pros and cons of VIP and its opportunities and challenges towards clinical applications to control HIV/AIDS endemics.…”
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643por Kulkarni, Chinmay, Sreekumar, K. P., Prabhu, Nirmal Kumar, kannan, Rajesh R, Moorthy, Srikanth“…Moreover, the tell-tale tumor blush can be obscured by proximity to lung base, small size of lesion, and breathing artifacts. C-arm CT is a revolutionary advancement in the intervention radiology suite that allows acquisition of data which can be reformatted in multiple planes and volume rendered incorporating both soft tissue and vascular information like multidetector computed tomography (MDCT). …”
Publicado 2014
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644“…In spite of the fact that physics and psychology are usually considered as unrelated, in the last century, both of these disciplines have led at the same time to revolutionary changes in the Western understanding of the cosmic order, discovering a non-empirical realm of the universe that doesn’t consist of material things but of forms. …”
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645“…Proteins are considered critical for the regulation of gene expression, which is a fundamental process in determining the cellular responses to stimuli. Recently, revolutionary findings in RNA research and the advent of high-throughput genomic technologies have revealed a pervasive transcription of the human genome, which generates many long non-coding RNAs (lncRNAs) whose roles are largely undefined. …”
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646“…Digital dental impression is a revolutionary technological advancement that so surpasses the accuracy and efficiency of former techniques for obtaining replicas of prepared teeth for the purpose of fabricating restorations that its adoption by dentists is rapidly eclipsing the use of elastomeric impression materials. …”
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647por Caputo, Massimo, Saif, Jaimy, Rajakaruna, Cha, Brooks, Marcus, Angelini, Gianni D., Emanueli, Costanza“…Hence, there is still scope for revolutionary new strategies to correct vascular anatomical defects. …”
Publicado 2015
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648por Gowran, Aoife, Rasponi, Marco, Visone, Roberta, Nigro, Patrizia, Perrucci, Gianluca L., Righetti, Stefano, Zanobini, Marco, Pompilio, Giulio“…A mere 9 years have passed since the revolutionary report describing the derivation of induced pluripotent stem cells from human fibroblasts and the first in-patient translational use of cells obtained from these stem cells has already been achieved. …”
Publicado 2016
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649“…Furthermore, there have been revolutionary, but somewhat controversial, advances in our understanding of stem cell biology. …”
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650por Martin, Francisco, Sánchez-Hernández, Sabina, Gutiérrez-Guerrero, Alejandra, Pinedo-Gomez, Javier, Benabdellah, Karim“…The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 endonuclease (Cas9) derived from bacterial adaptive immune systems is a revolutionary tool used in both basic and applied science. …”
Publicado 2016
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651por Chen, Xiang-Jun“…Switching magnetizations with femtosecond circularly polarized lasers may have revolutionary impacts on magnetic data storage and relevant applications. …”
Publicado 2017
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652“…Additive manufacturing (AM), nowadays commonly known as 3D printing, is a revolutionary materials processing technology, particularly suitable for the production of low-volume parts with high shape complexities and often with multiple functions. …”
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653por Fanotto, Valentina, Ongaro, Elena, Rihawi, Karim, Avallone, Antonio, Silvestris, Nicola, Fornaro, Lorenzo, Vasile, Enrico, Antonuzzo, Lorenzo, Leone, Francesco, Rosati, Gerardo, Giuliani, Francesco, Bordonaro, Roberto, Scartozzi, Mario, Maglio, Giovanna De, Negri, Francesca V., Fasola, Gianpiero, Aprile, Giuseppe“…HER-2 (ErbB-2, c-erbB2 or Her2/neu), a member of the HER-family, is directly involved in the pathogenesis and progression of several human cancers; as such, it is also often considered as a poor prognostic factor. Following the revolutionary impact of anti-HER-2 therapy in breast cancer patients, the role of HER-2 and its blockade has also been extensively evaluated in other tumor types, including gastric and colorectal adenocarcinoma. …”
Publicado 2016
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654“…Chimeric antigen receptor (CAR) T-cell therapy represents a revolutionary treatment for haematological malignancies (i.e. …”
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655“…Therefore, CRISPR/Cas is considered a revolutionary technology in plant biology. Here, we introduce the mechanism of the type II CRISPR/Cas called CRISPR/Cas9, update its recent advances in various applications in plants, and discuss its future prospects to provide an argument for its use in the study of medicinal plants.…”
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656“…The ability to build patient specific implants incorporated with bioactive drugs, cells, and proteins has made 3D printing technology revolutionary in medical and pharmaceutical fields. A vast variety of biomaterials are currently being used in medical 3D printing, including metals, ceramics, polymers, and composites. …”
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657“…Three-dimensional (3D) bio-printing is a revolutionary technology to reproduce a 3D functional living tissue scaffold in-vitro through controlled layer-by-layer deposition of biomaterials along with high precision positioning of cells. …”
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658por Chiulan, Ioana, Frone, Adriana Nicoleta, Brandabur, Călin, Panaitescu, Denis Mihaela“…3D printing represents a valuable alternative to traditional processing methods, clearly demonstrated by the promising results obtained in the manufacture of various products, such as scaffolds for regenerative medicine, artificial tissues and organs, electronics, components for the automotive industry, art objects and so on. This revolutionary technique showed unique capabilities for fabricating complex structures, with precisely controlled physical characteristics, facile tunable mechanical properties, biological functionality and easily customizable architecture. …”
Publicado 2017
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659por Barutello, Giuseppina, Rolih, Valeria, Arigoni, Maddalena, Tarone, Lidia, Conti, Laura, Quaglino, Elena, Buracco, Paolo, Cavallo, Federica, Riccardo, Federica“…In this panorama, the concept of comparative oncology acquires a priceless value. The revolutionary importance of spontaneous canine melanoma as a translational model for the pre-clinical investigation of melanoma progression and treatment will be here discussed, with a special consideration to the development of innovative immunotherapeutic approaches.…”
Publicado 2018
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660“…High-throughput sequencing is a revolutionary technology for the analysis of metagenomic samples. …”
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