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1161por Furukawa, Yoshiki, Hamano, Yasuharu, Shirane, Shuichi, Kinoshita, Shintaro, Azusawa, Yoko, Ando, Jun, Nakauchi, Hiromitsu, Ando, Miki“…However, the introduction of induced pluripotent stem cells (iPSCs) lessens such problems, and by using iPSC technology, unlimited numbers of allogeneic rejuvenated CTLs with robust and proliferative cytotoxic activity can be created. Despite this revolutionary concept, several concerns still exist, such as immunorejection by recipient cells and safety issues of gene editing. …”
Publicado 2022
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1162por Ganapathy, Krishnan, Rajagopalan, Arjun, Arjun, Gita, Suresh, Seshadri, Sriram, Krishnan“…Over the ensuing years, developments in information technology made the services redundant. Extensive, even revolutionary, changes such as universal digitization and availability of a cost-effective Internet radically changed how medical literature could be accessed in India.…”
Publicado 2022
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1163por Calado, Cecília R. C.“…Since the revolutionary finding of Helicobacter pylori as a common bacterial infection, that a high research effort for its eradication has been conducted. …”
Publicado 2022
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1164por Navarro-Ocón, Alba, Blaya-Cánovas, Jose L., López-Tejada, Araceli, Blancas, Isabel, Sánchez-Martín, Rosario M., Garrido, María J., Griñán-Lisón, Carmen, Calahorra, Jesús, Cara, Francisca E., Ruiz-Cabello, Francisco, Marchal, Juan A., Aptsiauri, Natalia, Granados-Principal, Sergio“…Despite the current revolutionary advances in the field of cancer immunotherapy, clinical response in breast cancer is frequently below expectations, in part due to various mechanisms of cancer immune escape that produce tumor variants that are resistant to treatment. …”
Publicado 2022
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1165“…In recent years, researchers have been investigating the revolutionary cancer treatment techniques of photodynamic therapy (PDT) and photothermal therapy (PTT) proposed by many scholars. …”
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1166por Ben Ayed, Rayda, Hanana, Mohsen, Ercisli, Sezai, Karunakaran, Rohini, Rebai, Ahmed, Moreau, Fabienne“…A new era of agriculture and food industry is forthcoming, with revolutionary concepts, processes and technologies, referred to as Agri-food 4.0, which enables the next level of agri-food production and trade. …”
Publicado 2022
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1167“…Archeogenetics has been revolutionary, revealing insights into demographic history and recent positive selection. …”
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1168“…Cryogenic electron microscopy (cryoEM) has emerged as a revolutionary method for solving high-resolution structures and studying the dynamics of macromolecular complexes and viruses in near-native states. …”
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1169“…Base editing has emerged as a revolutionary technology for single nucleotide modifications. …”
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1170por Huang, Chia-Ying, Aumonier, Sylvain, Engilberge, Sylvain, Eris, Deniz, Smith, Kate Mary Louise, Leonarski, Filip, Wojdyla, Justyna Aleksandra, Beale, John H., Buntschu, Dominik, Pauluhn, Anuschka, Sharpe, May Elizabeth, Metz, Alexander, Olieric, Vincent, Wang, Meitian“…Continuous developments in cryogenic X-ray crystallography have provided most of our knowledge of 3D protein structures, which has recently been further augmented by revolutionary advances in cryoEM. However, a single structural conformation identified at cryogenic temperatures may introduce a fictitious structure as a result of cryogenic cooling artefacts, limiting the overview of inherent protein physiological dynamics, which play a critical role in the biological functions of proteins. …”
Publicado 2022
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1171por Fülöp, Melinda Timea, Breaz, Teodora Odett, He, Xiaofei, Ionescu, Constantin Aurelian, Cordoş, George Silviu, Stanescu, Sorina Geanina“…In recent years, universities worldwide have experienced rapid changes with an immense impact, which have been influenced by technological progress and the social trends of digitalization. Like all other revolutionary changes, digital transformation involves intense adjustment/readjustment. …”
Publicado 2022
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1172“…Globally, the attainment of water and sanitation goals will be depended on economic development, the development of revolutionary measures for wastewater treatment, and creating awareness related to water usage, water recycling, water harvesting, hygiene, and sanitation. …”
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1173“…6G is already being planned and will employ much higher frequencies, leading to a revolutionary era in communication between people as well as things. …”
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1174por Christensen, Søren Brøgger“…In addition to terpenoids, recently discovered microtubule-targeting polyketide macrolides and non-ribosomal peptides have been discovered and marketed as drugs. The revolutionary improvements for treatment of cancer diseases targeting microtubules have led to an intensive search for other compounds with the same target. …”
Publicado 2022
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1175por Thacharon, Athira, Jang, Woo‐Sung, Kim, Jihyun, Kang, Joohoon, Kim, Young‐Min, Kim, Sung Wng“…This approach provides not only a revolutionary scheme to obtain MeNPs with non‐passivated and non‐oxidized surfaces, but also fundamental knowledge about metal oxidation.…”
Publicado 2022
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1176“…AI is revolutionizing computer vision, autonomous driving, natural language processing, and speech recognition. These revolutionary technologies are already impacting radiology, diagnostics, and other fields, where automated solutions can increase precision and reproducibility. …”
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1177“…This research proposal can be a revolutionary paradigm in identifying, classifying, modeling, and benefitting children and adolescents with a specific learning disorder (SLD). …”
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1178por Hamdan, Mohd Fadhli, Karlson, Chou Khai Soong, Teoh, Ee Yang, Lau, Su-Ee, Tan, Boon Chin“…We focus specifically on the CRISPR/Cas system, which has been the center of attention in the last few years as a revolutionary genome-editing tool in various species. …”
Publicado 2022
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1179“…Technological and scientific advances in the identification of molecular pathways that contribute to therapy-resistance and establishment of metastatic disease, have provided the rationale for revolutionary targeted approaches against Cyclin-Dependent Kinases 4/6 (CDK4/6), PI3 Kinase (PI3K), Poly ADP Ribose Polymerase (PARP) and Programmed Death-Ligand 1 (PD-L1), among others. …”
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1180por Zhao, Huangxuan, Zhou, Zhenghong, Wu, Feihong, Xiang, Dongqiao, Zhao, Hui, Zhang, Wei, Li, Lin, Li, Zhong, Huang, Jia, Hu, Hongyao, Liu, Chengbo, Wang, Tao, Liu, Wenyu, Ma, Jinqiang, Yang, Fan, Wang, Xinggang, Zheng, Chuansheng“…Our proposed method can help develop a revolutionary 3D-DSA reconstruction method for use in clinic.…”
Publicado 2022
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