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1221“…Since first sequencing the human genome in 2003, emerging genetic/genomic technologies have ushered in a revolutionary era of medicine that purports to bridge molecular biology and clinical care. …”
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1222por Chae, Heejoon, Jung, Inuk, Lee, Hyungro, Marru, Suresh, Lee, Seong-Whan, Kim, Sun“…The exponential increase of genomic data brought by the advent of the next or the third generation sequencing (NGS) technologies and the dramatic drop in sequencing cost have driven biological and medical sciences to data-driven sciences. This revolutionary paradigm shift comes with challenges in terms of data transfer, storage, computation, and analysis of big bio/medical data. …”
Publicado 2013
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1223por Vellayappan, Muthu Vignesh, Balaji, Arunpandian, Subramanian, Aruna Priyadarshini, John, Agnes Aruna, Jaganathan, Saravana Kumar, Murugesan, Selvakumar, Supriyanto, Eko, Yusof, Mustafa“…Major drawbacks related to the use of biomaterials are their mechanical properties and biocompatibility, and these have to be circumvented before promoting the material to the market or clinical setting. Revolutionary advancements in nanotechnology have introduced a novel class of materials called nanocomposites which have superior properties for biomedical applications. …”
Publicado 2015
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1224“…The advent of nutritional systems biology, a field that aims to elucidate the interactions between dietary nutrients and endogenous molecular entities in disease-related tissues, offers unique opportunities to unravel the complex mechanisms underlying the health-modifying capacities of nutritional molecules. The recent revolutionary advances in omics technologies have particularly empowered this incipient field. …”
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1225por Risse, Judith, Thomson, Marian, Patrick, Sheila, Blakely, Garry, Koutsovoulos, Georgios, Blaxter, Mark, Watson, Mick“…The Oxford Nanopore MinION device is a revolutionary mobile sequencer that can produce thousands of long, single molecule reads. …”
Publicado 2015
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1226por Zhao, Yi, Li, Hui, Fang, Shuangsang, Kang, Yue, wu, Wei, Hao, Yajing, Li, Ziyang, Bu, Dechao, Sun, Ninghui, Zhang, Michael Q., Chen, Runsheng“…The recently reduced cost of RNA sequencing has produced an explosion of newly identified data. Revolutionary third-generation sequencing methods have also contributed to more accurate annotations. …”
Publicado 2016
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1227por Lin, Benchuan, Chen, Bokui, Gao, Yachun, Tse, Chi K., Dong, Chuanfei, Miao, Lixin, Wang, Binghong“…More importantly, in comparison with global routing strategies, the improved local routing strategies can yield better network performance under certain circumstances. This is a revolutionary leap for communication networks, because local routing strategy enjoys great superiority over global routing strategy not only in terms of the reduction of computational expense, but also in terms of the flexibility of implementation, especially for large-scale networks.…”
Publicado 2016
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1228por Thurrowgood, David, Paterson, David, de Jonge, Martin D., Kirkham, Robin, Thurrowgood, Saul, Howard, Daryl L.“…Rapid technological advances are forging connections between scientists and arts communities, enabling revolutionary new techniques for non-invasive technical study of culturally significant, highly prized artworks. …”
Publicado 2016
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1229“…Thus, we obtained high purity silver and nickel layers with a conductivity two times greater than could be obtained with state-of-the-art, commercial materials. This revolutionary concept can be easily applied to other systems using inorganic or even organic conductive particles and represents a fundamental paradigm change to the formulation of pastes for printed electronics.…”
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1230por BYFORD, ANDY“…While Bekhterev's prominence in this field is beyond doubt, analysis shows that “objective psychology” and “reflexology” had much less success in mobilizing support within it than certain other movements in this arena (for example, “experimental pedagogy” in the pre‐revolutionary era); it also found it difficult to compete with the variety of rival programs that arose within Soviet “pedology” during the 1920s. …”
Publicado 2016
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1231por Baeumer, Christoph, Schmitz, Christoph, Marchewka, Astrid, Mueller, David N., Valenta, Richard, Hackl, Johanna, Raab, Nicolas, Rogers, Steven P., Khan, M. Imtiaz, Nemsak, Slavomir, Shim, Moonsub, Menzel, Stephan, Schneider, Claus Michael, Waser, Rainer, Dittmann, Regina“…The continuing revolutionary success of mobile computing and smart devices calls for the development of novel, cost- and energy-efficient memories. …”
Publicado 2016
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1232por Wang, Qiu, Zhang, Xueqian, Xu, Yuehong, Gu, Jianqiang, Li, Yanfeng, Tian, Zhen, Singh, Ranjan, Zhang, Shuang, Han, Jiaguang, Zhang, Weili“…As a revolutionary three-dimensional imaging technique, holography has attracted wide attention for its ability to photographically record a light field. …”
Publicado 2016
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1233“…Mesenchymal stem cells (MSCs) represent a potentially revolutionary therapy for a wide variety of pediatric diseases, but the optimal cell‐based therapeutics for such diversity have not yet been specified. …”
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1234por Scazzocchio, Claudio“…The “next generation” sequencing techniques have produced a further qualitative revolutionary change. The ready access to genomes and transcriptomes of any microbial organism allows old questions to be asked in a radically different way and new questions to be approached. …”
Publicado 2014
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1235“…These methods have been revolutionary for quantitative analysis of the mammalian brain, in which volumetric cell populations are too high to count manually, and stereology is now the technique of choice whenever estimates of three-dimensional quantities need to be extracted from measurements on two-dimensional sections. …”
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1236“…Our article explores this egregious ethical failure by reviewing EFM’s lack of clinical efficacy, discussing the EFM related harm to mothers and babies, and focusing on the reasons that this obstetrical procedure eluded the revolutionary change from the Hippocratic tradition to autonomy through informed consent.…”
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1237por Kelm, M., Seyfried, F., Reimer, S., Krajinovic, K., Miras, A.D., Jurowich, C., Germer, C.T., Brand, M.“…Endoluminal vacuum (EndoVAC™) therapy has been shown to be a revolutionary option but has anatomical and technical limits. …”
Publicado 2017
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1238“…They have wide potential compared to classical genetic engineering and they are attracting the interest of politicians, stakeholders and citizens due to the revolutionary impact they may have on agriculture. Cisgenesis and genome editing potentially allow to obtain pathogen-resistant plants or plants with enhanced qualitative traits by introducing or disrupting specific genes in shorter times compared to traditional breeding programs and by means of minimal modifications in the plant genome. …”
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1239por Del Vecchio, Filippo, Mastroiaco, Valentina, Di Marco, Antinisca, Compagnoni, Chiara, Capece, Daria, Zazzeroni, Francesca, Capalbo, Carlo, Alesse, Edoardo, Tessitore, Alessandra“…The introduction of next-generation sequencing (NGS) represents a revolutionary step and promises to lead to massive improvements in our understanding on the role of nucleic acids functions. …”
Publicado 2017
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1240“…This article will provide a concise opinion on the state‐of‐the‐art, the challenges, and the use of systems biology—another equally revolutionary field of science—to assess the unique health hazards of nanomaterial exposures. …”
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