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  1. 1401
    “…OBJECTIVE(S): Checkpoint blocking is considered a revolutionary method in cancer treatment. This method eliminates cancer cells by maintaining the sensitivity of immune cells. …”
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    Use of dual-transfection for programmed death cell protein 1 disruption mediated by CRISPR-Cas9 in human peripheral blood mononuclear cells
  2. 1402
    “…Chimeric antigen receptor (CAR)-T cell therapy is a revolutionary new pillar in cancer treatment. Although treatment with CAR-T cells has produced remarkable clinical responses with certain subsets of B cell leukemia or lymphoma, many challenges limit the therapeutic efficacy of CAR-T cells in solid tumors and hematological malignancies. …”
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    CAR-T cell therapy: current limitations and potential strategies
  3. 1403
    “…The growth of pulsed electromagnetic field (PEMF) therapy and its progress over the years for use in post-operative bone growth has been revolutionary in its effect on bone tissue proliferation and vascular flow. …”
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    Pulsed Electromagnetic Field Stimulators Efficacy for Noninvasive Bone Growth in Spine Surgery
  4. 1404
    “…In summary, targeting GSCs provides a tremendous opportunity for revolutionary approaches to improve the prognosis and therapy of GBM, despite a variety of challenges.…”
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    Targeting Glioblastoma Stem Cells: A Review on Biomarkers, Signal Pathways and Targeted Therapy
  5. 1405
    “…Herein, we explore the current state of preclinical and clinical evidence supporting the use of stem cells in treating PMS and we discuss prospective hurdles impeding their translation into revolutionary regenerative medicines.…”
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    Stem Cell Therapies for Progressive Multiple Sclerosis
  6. 1406
    “…Our work provides a revolutionary technology for the growth of high-quality semiconductors, thus enabling the hetero-integration of highly mismatched material systems.…”
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    Van der Waals epitaxy of nearly single-crystalline nitride films on amorphous graphene-glass wafer
  7. 1407
    por Roseman, Leor, Karkabi, Nadeem
    Publicado 2021
    “…Badiou’s theory elucidates the egalitarian revolutionary potential, which is part of the sociopsychopharmacology of psychedelics.…”
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    On Revelations and Revolutions: Drinking Ayahuasca Among Palestinians Under Israeli Occupation
  8. 1408
    “…Notably, the transfer of autonomy and power over health decision-making processes is emphasized, which will require revolutionary thinking about how healthcare is delivered for patients.…”
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    Community-engaged healthcare model for currently under-served individuals involved in the healthcare system
  9. 1409
    “…A vascularized fibula graft incorporates this revolutionary approach with a traditional massive allograft to reconstruct large femur and tibia defects during oncological resection. …”
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    Periosteal ostoesarcoma of the femur treated with modified capanna procedure: A case report
  10. 1410
    por Suzuki, Yuta, Ishihara, Hiroshi
    Publicado 2021
    “…Lipid nanoparticles (LNPs) have provided a revolutionary delivery system that can ensure multiple clinical translation of RNA-based candidates. …”
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    Difference in the lipid nanoparticle technology employed in three approved siRNA (Patisiran) and mRNA (COVID-19 vaccine) drugs
  11. 1411
    “…Overall, the application of nanotechnology could bring a revolutionary change to the current treatment of liver cancer.…”
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    Engineering nanotheranostic strategies for liver cancer
  12. 1412
    “…The revolutionary technology of CRISPR/Cas systems and their extraordinary potential to address fundamental questions in every field of biological sciences has led to their developers being awarded the 2020 Nobel Prize for Chemistry. …”
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    An Outlook on Global Regulatory Landscape for Genome-Edited Crops
  13. 1413
    por Li, Yanyan, Guo, Mengmeng
    Publicado 2021
    “…Specifically, two decades before and after the year 2000 was taken into account as it comprised the most noticeable revolutionary developments in terms of economics, technology, culture, and society. …”
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    Scientific Literacy in Communicating Science and Socio-Scientific Issues: Prospects and Challenges
  14. 1414
    “…The discovery validated that Mtb PknH 273–280 (N′-HEALSDPD-C′) has reliable EmbR binding affinity. This approach is revolutionary in the computer-aided drug discovery field, because it is the first trial to discover the protein-protein interaction site, and find binding partner in nature from this site.…”
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    Computational prediction and validation of specific EmbR binding site on PknH
  15. 1415
    “…"Prevention", a component of primary health care since Alma Atas declaration (1978), has been a strategic axis of health policy in Tunisia for four decades. If the Tunisian Revolutionary Constitution (2014) declared in its Article 38 that "the State guarantees prevention", the regulatory texts, organizing preventive structures and its operational programs, have today become ill-suited with the global burden of disease and current scientific evidence. …”
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    Vers des nouvelles perspectives d'appui à la Prévention au Système National de la Santé, en Tunisie
  16. 1416
    “…The epigenetic landscape is remodeled with age, bringing about widespread consequences for cell function. With the revolutionary discoveries by Yamanaka and Takahashi, as well as those that built on this work, the transcription factors Oct4, Sox2, KLF4, and C-Myc (OSKM) can be expressed in a variety of cells, including fibroblasts, to make iPSCs. …”
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    Epigenetic Trajectories of Aging and Reprogramming
  17. 1417
    “…Anterior cervical surgery (ACS) owes its development to various pioneering individuals whose revolutionary works form key advances and guide current medical decisions. …”
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    Bibliometric and visualized analysis of the top 100 most-cited articles on anterior cervical surgery
  18. 1418
    “…That enables the use of AgNPs decorated C(60) endo fullerene molecules to design an effective anti-cancerous drug delivery and antimicrobial agent in the future, bringing a revolutionary change in the perspective of a treatment regime.…”
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    Exploring the Bioactive Potentials of C(60)-AgNPs Nano-Composites against Malignancies and Microbial Infections
  19. 1419
    “…With the creation of a low-cost, cyber–physical system that interrogates and classifies the mechanical health of given surfaces, we lower the cost of SHM, decrease the challenges faced when conducting such tests, and enable communities with a revolutionary solution that is adaptable to their needs. …”
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    Use of Remote Structural Tap Testing Devices Deployed via Ground Vehicle for Health Monitoring of Transportation Infrastructure
  20. 1420
    “…To overcome DR, manual diagnosis of the disease is feasible but overwhelming and cumbersome at the same time and hence requires a revolutionary method. Thus, such a health condition necessitates primary recognition and diagnosis to prevent DR from developing into severe stages and prevent blindness. …”
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    A critical review on diagnosis of diabetic retinopathy using machine learning and deep learning
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