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  1. 1521
    “…RNA sequencing (RNA-seq) has revolutionary roles in transcriptome identification and quantification of different types of tissues and cells in many organisms. …”
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    Comparative Transcriptome Analysis Reveals Substantial Tissue Specificity in Human Aortic Valve
  2. 1522
    “…Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step changes in our understanding of malaria parasite (Plasmodium spp.) biology and its interactions with its host and vector. …”
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    Recent advances in malaria genomics and epigenomics
  3. 1523
    “…Chirped pulse amplification in optical lasers is a revolutionary technique, which allows the generation of extremely powerful femtosecond pulses in the infrared and visible spectral ranges. …”
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    Chirped pulse amplification in an extreme-ultraviolet free-electron laser
  4. 1524
    “…Technological innovations in endoscopy have led to revolutionary developments in many areas. Flexible spectral imaging color enhancement (FICE) and narrow-band imaging (NBI) are forms of digital chromoendoscopy and enhance the endoscopic images without the need for a dye. …”
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    FICE vs Narrow Band Imaging for In Vivo Histologic Diagnosis of Polyps
  5. 1525
    “…The use of combined Anti-Retroviral Therapy (cART) has been revolutionary in the history of the fight against HIV-AIDS, with remarkable reductions in HIV associated morbidity and mortality. …”
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    Ethical implications of HIV self-testing: the game is far from being over
  6. 1526
    “…The CRISPR/Cas9 system provides a revolutionary genome editing tool for all areas of molecular biology. …”
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    Challenges of CRISPR/Cas9 applications for long non-coding RNA genes
  7. 1527
    “…BACKGROUND: Neurite orientation dispersion and density imaging (NODDI) is a diffusion magnetic resonance imaging (MRI) technique with the potential to visualize the microstructure of the brain. Revolutionary histological methods to render the mouse brain transparent have recently been developed, but verification of NODDI by these methods has not been reported. …”
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    Understanding microstructure of the brain by comparison of neurite orientation dispersion and density imaging (NODDI) with transparent mouse brain
  8. 1528
    por Serkova, Natalie J.
    Publicado 2017
    “…As such, non-invasive imaging of cancer inflammation and tumor-associated macrophages (TAMs) provides a revolutionary diagnostic tool and monitoring strategy for anti-inflammatory, immuno- and radiotherapies. …”
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    Nanoparticle-Based Magnetic Resonance Imaging on Tumor-Associated Macrophages and Inflammation
  9. 1529
    “…CONCLUSION: The new type of non-mydriatic portable fundus camera was qualified to have professional quality of fundus images. The revolutionary screening camera provides a foundational platform which can potentially improve the accessibility of retinal screening programmes.…”
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    Telemedicine screening of retinal diseases with a handheld portable non-mydriatic fundus camera
  10. 1530
    por Kevin Baird, J.
    Publicado 2017
    “…This practical malariology achieved very significant reductions in burdens of morbidity and mortality, but the revolutionary insecticide eliminated the need for its specialized knowledge and diverse practices. …”
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    Malaria control by commodities without practical malariology
  11. 1531
    “…Identifying targets that benefit from angiogenesis treatment is indispensable for the development of revolutionary therapies. Here, we describe a novel circulatory system wherein new vessels develop from the endocardium of the left ventricle to perfuse the hypoxic area and salvage damaged cardiomyocytes at 3–14 days after MI by activating vascular endothelial growth factor signaling. …”
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    Dynamics of angiogenesis in ischemic areas of the infarcted heart
  12. 1532
    “…The great potential of this revolutionary concept for the attainment of pressure-distribution sensing on a macroscale area could expand its use to not only e-skin applications but to other high-end applications such as touch panels, portable flexible keyboard, sign language interpreting globes, safety diagnosis of social infrastructures, and the diagnosis of motility and peristalsis disorders in the gastrointestinal tract.…”
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    An extremely simple macroscale electronic skin realized by deep machine learning
  13. 1533
    por Saleh, Razwa, Reza, Hasan Mahmud
    Publicado 2017
    “…These cells have high proliferative capacity and their superior harvest and multiplication, using the revolutionary CellOptima(TM) technology, makes them better candidates in comparison to contemporary adult stem cells. …”
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    Short review on human umbilical cord lining epithelial cells and their potential clinical applications
  14. 1534
    por Cutas, Daniela, Smajdor, Anna
    Publicado 2016
    “…Indeed, in some respects it is less revolutionary than in vitro fertilisation as a whole. …”
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    “I am Your Mother and Your Father!” In Vitro Derived Gametes and the Ethics of Solo Reproduction
  15. 1535
    “…The past two decades have witnessed the revolutionary development of optical trapping of nanoparticles, most of which deal with trapping stiffness larger than 10(−8) N/m. …”
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    Nanometer-precision linear sorting with synchronized optofluidic dual barriers
  16. 1536
    por Shirakawa, Toshiro, Kitagawa, Koichi
    Publicado 2017
    “…Despite the revolutionary progress of immune checkpoint inhibitors (CPIs) for cancer immunotherapy, CPIs are effective only in a subset of patients. …”
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    Antitumor effect of oral cancer vaccine with Bifidobacterium delivering WT1 protein to gut immune system is superior to WT1 peptide vaccine
  17. 1537
    “…Our study is also a step toward raising awareness about mitochondrial diseases and advocating for the legalization of mitochondrial donation, a revolutionary in vitro fertilization technique.…”
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    Mitochondrial Donation: A Boon or Curse for the Treatment of Incurable Mitochondrial Diseases
  18. 1538
    por Wang, Rong, Zhou, Tingyang, Liu, Wei, Zuo, Li
    Publicado 2018
    “…A clinical consideration of NTEs could have a revolutionary impact on current radiotherapy via the establishment of more efficient and less toxic radiobiological models for treatment planning compared to conventional models. …”
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    Molecular mechanism of bystander effects and related abscopal/cohort effects in cancer therapy
  19. 1539
    “…The analysis of DNA has led to revolutionary advancements in the fields of medical diagnostics, genomics, prenatal screening, and forensic science, with the global DNA testing market expected to reach revenues of USD 10.04 billion per year by 2020. …”
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    Self-reference and random sampling approach for label-free identification of DNA composition using plasmonic nanomaterials
  20. 1540
    “…Rather than because of any significant advantages in quality, it was the potential for increased quantities of production, inherent in the shift from gathered wild Asclepias bast fibers to cultivated cotton, that inadvertently precipitated revolutionary social change. Thereby refined, the MFAC hypothesis duly emerges more persuasive than ever.…”
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    Refining the Maritime Foundations of Andean Civilization: How Plant Fiber Technology Drove Social Complexity During the Preceramic Period
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