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  1. 2241
    “…The higher ratios are similar to seawater strontium ratios in the Neogene. (87)Sr/(86)Sr ratios lower 0.7084 indicate exchange of Sr with the igneous host rock. The calcite veins hosted by the sedimentary rocks are showing more primitive (87)Sr/(86)Sr ratios <0.706396. …”
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    The Origin of Carbonate Veins Within the Sedimentary Cover and Igneous Rocks of the Cocos Ridge: Results From IODP Hole U1414A
  2. 2242
    “…Owing to an adaptive mesh generation technique and appropriate boundary conditions, rock permeability and mobility are accurately computed. …”
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    The Effect of Heat Transfer and Polymer Concentration on Non-Newtonian Fluid from Pore-Scale Simulation of Rock X-ray Micro-CT
  3. 2243
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    “What’s happening in Syria even affects the rocks”: a qualitative study of the Syrian refugee experience accessing noncommunicable disease services in Jordan
  4. 2244
    “…Oxymatrine (OMT) is an important quinoxaline alkaloid that has a wide range of pharmacological effects and has been shown to alleviate ulcerative colitis due to its profound anti-inflammatory effects. The RhoA/ROCK (Rho kinase) signaling pathway has been shown to be related to the pathogenesis of several autoimmune diseases; however, the specific mechanisms of RhoA/ROCK signaling in inflammatory bowel disease (IBD) remain elusive. …”
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    Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway
  5. 2245
    “…To study the mining-induced failure depth of floor rocks in a fully mechanized mining caving field affected by different coal seam pitches, mining face lengths, burial depths and aquifer water pressures, multifactor-coupled orthogonal numerical tests on the failure depth of floor rocks were conducted. …”
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    A multifactor coupling prediction model for the failure depth of floor rocks in fully mechanized caving mining: a numerical and in situ study
  6. 2246
    “…Importantly, we found that ROCK1 was activated in an MPP(+)-induced PD cell model and that ROCK1 knockdown and the specific ROCK1 activation inhibitor Y-27632 blocked Drp1-mediated aberrant mitochondrial fission and apoptosis of dopaminergic nerve cells by suppressing Drp1 dephosphorylation/activation. …”
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    ROCK1 induces dopaminergic nerve cell apoptosis via the activation of Drp1-mediated aberrant mitochondrial fission in Parkinson’s disease
  7. 2247
    “…PURPOSE: To observe the changes of Nogo/NgR and Rho/ROCK signaling pathway-related gene and protein expression in rats with spinal cord injury (SCI) treated with electroacupuncture (EA) and to further investigate the possible mechanism of EA for treating SCI. …”
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    Electroacupuncture Promoting Axonal Regeneration in Spinal Cord Injury Rats via Suppression of Nogo/NgR and Rho/ROCK Signaling Pathway
  8. 2248
    “…PURPOSE: Our previous studies have indicated that non-muscle myosin heavy chain IIA (NMMHC IIA) is involved in H(2)O(2)-induced neuronal apoptosis, which is associated with the positive feedback loop of caspase-3/ROCK1/MLC pathway. However, the neuroprotective effect of NMMHC IIA inhibition with an adeno-associated virus (AAV) vector after transient middle cerebral artery occlusion (MCAO) and its role in caspases-3/ROCK1/MLC pathway remain blurred. …”
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    NMMHC IIA Inhibition Ameliorates Cerebral Ischemic/Reperfusion-Induced Neuronal Apoptosis Through Caspase-3/ROCK1/MLC Pathway
  9. 2249
    “…Moreover, we found distinct roles of ROCK1, ROCK2 and PAK in regulating Vimentin phosphorylation. …”
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    Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling
  10. 2250
    “…As a common solid waste in geotechnical engineering, rock granular material should be properly treated and recycled. …”
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    The variation of grain size distribution in rock granular material in seepage process considering the mechanical–hydrological–chemical coupling effect: an experimental research
  11. 2251
    “…Moreover, we demonstrated that phagocytosis induced by the inhibition of the RhoA-ROCK1 pathway leads to Nfix expression and, consequently, to acquisition of the anti-inflammatory phenotype. …”
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    The Transcription Factor Nfix Requires RhoA-ROCK1 Dependent Phagocytosis to Mediate Macrophage Skewing during Skeletal Muscle Regeneration
  12. 2252
    por Liu, Jinyang, Zhu, Yaqin, Ge, Chunlin
    Publicado 2020
    “…Dual-luciferase reporter assays were used to confirm the binding of ZFAS1/miR-3924 and miR-3924/ROCK2, and rescue assays were performed to further investigate the underlying mechanism. …”
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    LncRNA ZFAS1 promotes pancreatic adenocarcinoma metastasis via the RHOA/ROCK2 pathway by sponging miR-3924
  13. 2253
    “…Silencing of SNHG7 could attenuate deposition of collagens and improve cardiac function. miR-34-5p could suppress the fibrogenesis of CF by targeting ROCK1 and abolish SNHG7-induced CF proliferation and fibroblast-to-myofibroblast transition.…”
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    LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p
  14. 2254
    por Zhang, Zhi, Yu, Tao, Geng, Wei
    Publicado 2020
    “…ROCK1 overexpression attenuated the role of CCHE1. …”
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    Long non-coding RNA CCHE1 participates in postoperative distant recurrence but not local recurrence of osteosarcoma possibly by interacting with ROCK1
  15. 2255
    por Zhao, Yilei, Xu, Jingfeng
    Publicado 2020
    “…Moreover, the expressions of apoptosis-related and RhoA/ROCK signaling-related proteins were detected through western blotting. …”
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    Sanggenon C Ameliorates Cerebral Ischemia-Reperfusion Injury by Inhibiting Inflammation and Oxidative Stress through Regulating RhoA-ROCK Signaling
  16. 2256
    “…Mechanically, we found that HAGLROS sponged miR-152 to promote ROCK1 expression in U2OS and SW1353 cells. CONCLUSION: In summary, our study indicated that HAGLROS could promote osteosarcoma progression by sponging miR-152 to promote ROCK1 expression. …”
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    Long Noncoding RNA HAGLROS Promotes Cell Invasion and Metastasis by Sponging miR-152 and Upregulating ROCK1 Expression in Osteosarcoma
  17. 2257
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    Between a Rock and a Hard Place – Gender Dysphoria and Comorbid Depression in a Young, Low-Income, Pakistani Transgender Man
  18. 2258
    por Goral, Jan, Deo, Milind
    Publicado 2020
    “…Using this technology, a creation of the first nano-3D-printed digital (shale) rock is reported. In this paper, focused ion beam-scanning electron microscopy (FIB-SEM) nano-tomography image dataset was used to reconstruct a high-resolution digital rock 3D model of a Marcellus Shale rock sample. …”
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    Nanofabrication of synthetic nanoporous geomaterials: from nanoscale-resolution 3D imaging to nano-3D-printed digital (shale) rock
  19. 2259
    “…Thus, the Nrf2/Keap1 pathway may affect cell motility by dysregulating the RhoA–ROCK1 signalling pathway in NSCLC.…”
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    Nrf2 regulates cell motility through RhoA–ROCK1 signalling in non-small-cell lung cancer cells
  20. 2260
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    WITHDRAWN: Special Issue on innovative methods for characterizing evolution and budgets in water – rock systems: A tribute to Tom Bullen and Stepan Shvartsev
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