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2341AB250. Annexin V-induced rat Leydig cell proliferation involves Ect2 via RhoA/ROCK signaling pathwaypor Yao, Bin“…Moreover, inhibition of the RhoA/ROCK pathway by a ROCK inhibitor, Y27632, also attenuated annexin V-induced proliferation and cell cycle progression. …”
Publicado 2016
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2342“…These data suggest that the Rho/ROCK signaling pathway is involved in HIV-1 Tat-mediated changes in occludin, RAGE, and LRP1 in hCMEC/D3 cells. …”
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2343por Zhang, Yanhao, Fu, Ruoqiu, Liu, Yanxia, Li, Jing, Zhang, Hongwei, Hu, Xiaoye, Chen, Yibiao, Liu, Xin, Li, Yunong, Li, Ping, Liu, Ehu, Gao, Ning“…These data are consistent with a hierarchical model in which induction of apoptosis by cerulenin primarily results from activation of ROCK1, inactivation of Akt, and activation of JNK. …”
Publicado 2016
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2344por Lee, Jaejin, Cho, Ahnna, Yang, Jae Young, Woo, Jusun, Lee, Hong Kum, Hong, Soon Gyu, Kim, Ok-Sun“…Cryobacterium arcticum PAMC 27867, a psychrotolerant, Gram-positive bacterium, was isolated from a sedimentary rock sample collected at Eureka Spurs in northern Victoria Land, Antarctica. …”
Publicado 2016
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2345por Iskit, Sedef, Lieftink, Cor, Halonen, Pasi, Shahrabi, Aida, Possik, Patricia A., Beijersbergen, Roderick L., Peeper, Daniel S.“…These results illustrate the power of in vivo genetic screens and warrant further validation of EGFR and ROCK as combined pharmacologic targets for breast cancer.…”
Publicado 2016
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2346por Zhang, X, Zhang, L, Du, Y, Zheng, H, Zhang, P, Sun, Y, Wang, Y, Chen, J, Ding, P, Wang, N, Yang, C, Huang, T, Yao, X, Qiao, Q, Gu, H, Cai, G, Cai, S, Zhou, X, Hu, W“…However, the underlying mechanisms for ROCKs activation are not fully understood. Here, we identified FOXM1D, a novel isoform of Forkhead box M1 (FOXM1) that has a pivotal role in ROCKs activation by directly interacting with coiled-coil region of ROCK2. …”
Publicado 2017
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2347“…Rock bolts, as a type of reinforcing element, are widely adopted in underground excavations and civil engineering structures. …”
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2348por Bell, Michael, Sopko, Nikolai A., Matsui, Hotaka, Hannan, Johanna L., Bivalacqua, Trinity J.Enlace del recurso
Publicado 2017
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2349“…These results suggest that EA provides a less inhibitory environment for axonal regeneration following cerebral ischemia through inhibition of Nogo-A/NgR/RhoA/ROCK signaling.…”
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2351“…This study examined associations between rock climbing and acute emotion regulating effects in patients with major depression. …”
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2352por Quarta, Serena, Camprubí-Robles, Maria, Schweigreiter, Rüdiger, Matusica, Dusan, Haberberger, Rainer V., Proia, Richard L., Bandtlow, Christine E., Ferrer-Montiel, Antonio, Kress, Michaela“…Adult sensory neurons and motor neuron-like cells were exposed to S1P in an in vitro assay, and virtually all neurons responded with a rapid retraction of neurites and growth cone collapse which were associated with RhoA and ROCK activation. The S1P(1) receptor agonist SEW2871 neither activated RhoA or neurite retraction, nor was S1P-induced neurite retraction mitigated in S1P(1)-deficient neurons. …”
Publicado 2017
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2353por Guerra, Fabiana Sélos, Oliveira, Ramon Guerra de, Fraga, Carlos Alberto Manssour, Mermelstein, Claudia dos Santos, Fernandes, Patricia Dias“…MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility involving cytoskeleton regulation through stabilization of actin filaments and stress fiber formation. …”
Publicado 2017
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2354“…Joints and fissures in natural rocks have a significant influence on the stability of the rock mass, and it is often necessary to evaluate strength failure and crack evolution behavior. …”
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2355por Campbell, Hamish, Fleming, Nicholas, Roth, Imogen, Mehta, Sunali, Wiles, Anna, Williams, Gail, Vennin, Claire, Arsic, Nikola, Parkin, Ashleigh, Pajic, Marina, Munro, Fran, McNoe, Les, Black, Michael, McCall, John, Slatter, Tania L., Timpson, Paul, Reddel, Roger, Roux, Pierre, Print, Cristin, Baird, Margaret A., Braithwaite, Antony W.“…We also show that ∆122p53 activates RhoA-ROCK signalling leading to tumour cell invasion, which is IL-6-dependent and can be reduced by inhibition of JAK-STAT and RhoA-ROCK pathways. …”
Publicado 2018
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2356por Kim, Kue-Young, Oh, Junho, Han, Weon Shik, Park, Kwon Gyu, Shinn, Young Jae, Park, Eungyu“…This study presents, for the first time, a two-phase (CO(2) and brine) flow visualization under reservoir conditions (10 MPa, 50 °C) for a highly heterogeneous conglomerate core obtained from a real CO(2) storage site. Rock heterogeneity and the porosity variation characteristics were evaluated using X-ray computed tomography (CT). …”
Publicado 2018
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2357por Li, Yuan, Li, Quan, Pan, Chun-Shui, Yan, Li, Hu, Bai-He, Liu, Yu-Ying, Yang, Lei, Huang, Ping, Zhao, Shao-Yang, Wang, Chuan-She, Fan, Jing-Yu, Wang, Xue-Mei, Han, Jing-Yan“…These results indicate that the protective effect of BSHX on T2DM-induced cognitive impairment involves regulation of RhoA/ROCK1/moesin signaling pathway and phosphorylation of Src kinase.…”
Publicado 2018
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2358por Chen, Xueran, Zhang, Shangrong, Wang, Zhen, Wang, Fengsong, Cao, Xinwang, Wu, Quan, Zhao, Chenggang, Ma, Huihui, Ye, Fang, Wang, Hongzhi, Fang, Zhiyou“…RESULTS: Hypoxia-induced upregulation of supervillin promoted cancer cell migration and invasion via the activation of the ERK/p38 pathway downstream of RhoA/ROCK signaling. Furthermore, supervillin regulated the expression of EMT genes during hypoxia and accelerated the metastasis of HCC in vivo. …”
Publicado 2018
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2359por Matsubayashi, Makoto, Tsuchida, Sayaka, Kobayashi, Atsushi, Shibahara, Tomoyuki, Nakamura, Hiroshi, Murata, Koichi, Ushida, Kazunari“…Thus far, two types of Eimeria parasites (E. uekii and type B) have been morphologically identified in wild Japanese rock ptarmigans, Lagopus muta japonica. Although high prevalences were reported for these parasites, genetic analyses have not been conducted. …”
Publicado 2018
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2360por Brumm, Adam, Hakim, Budianto, Ramli, Muhammad, Aubert, Maxime, van den Bergh, Gerrit D., Li, Bo, Burhan, Basran, Saiful, Andi Muhammad, Siagian, Linda, Sardi, Ratno, Jusdi, Andi, Abdullah, Mubarak, Andi Pampang, Moore, Mark W., Roberts, Richard G., Zhao, Jian-xin, McGahan, David, Jones, Brian G., Perston, Yinika, Szabó, Katherine, Mahmud, M. Irfan, Westaway, Kira, Jatmiko, Saptomo, E. Wahyu, van der Kaars, Sander, Grün, Rainer, Wood, Rachel, Dodson, John, Morwood, Michael J.Enlace del recurso
Publicado 2018
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