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2481por Komissarov, Aleksey, Korchagin, Vitaly, Kliver, Sergei, Dobrynin, Pavel, Semyenova, Serafima, Vergun, Andrey, O’Brien, Stephen, Ryskov, Alexey“…The first complete mitochondrial genome sequence of parthenogenetic Caucasian rock lizard Darevskia unisexualis (Lacertidae family) is determined by hybrid assembly with Illumina HiSeq and PacBio RS II platforms. …”
Publicado 2016
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2482“…Western blot analysis was used to detect ROCK1 and NFATc3 protein levels. In addition, reverse transcription-quantitative (RT-q) PCR was performed to confirm the mRNA levels of miR-153, ROCK1 and NFATc3 in human (H)PASMCs under hypoxic conditions. …”
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2483por Hamdali, Hanane, Lebrihi, Ahmed, Monje, Marie Carmen, Benharref, Ahmed, Hafidi, Mohamed, Ouhdouch, Yedir, Virolle, Marie Joëlle“…Some soil-borne microorganisms are known to have the ability to solubilize insoluble rock phosphate and this process often involves the excretion of organic acids. …”
Publicado 2021
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2484por Sadic, Edin, Morales, Jose Ruiz, Missov, Emil, Percy, Robert, Sattiraju, SrinivasanEnlace del recurso
Publicado 2021
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2485por Chen, Lijuan, Lan, Chengzhong, Xiao, Hong, Zhang, Xiaoli, Qi, Xiangrong, Ouyang, Li, Yang, Yanbin, Wang, Fengying, Jin, Qihua, Sun, Yi“…BACKGROUND: Rho-related coiled helix forming protein kinase (Rho-ROCK) and another important fibrogenic factor-PDGF play a critical role in collagen deposition in rat lung tissue. …”
Publicado 2021
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2486por Lebedev, Evgeny B., Kern, Hartmut, Pavlenkova, Ninely I., Lukanin, Oleg A., Lobanov, Konstantin V., Zharikov, Andrey V., Popp, Till“…It is shown that the most significant decrease of velocities (by ~ 3 km/s) in the temperature range of 400–700 °C, corresponding to the deep waveguides of the lithospheric mantle, occurs under water pressure in ultramafic rocks enriched by olivine (dunites). Such decrease is due to rock structure changes caused by olivine serpentinization reactions. …”
Publicado 2021
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2487
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2488por Abdullah, Fowzia H.“…They were formed at later stages by meteoric water dissolution, acidic gases produced during the thermal maturation of kerogen in the petroleum source rocks, or a combination of both processes. The results of this study may be applicable to analogous subsurface carbonate reservoir rocks.…”
Publicado 2021
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2489por Shea, Kevin, Liotta, Elizabeth, Hergott, Katelyn, Wall, Eric, Myer, Greg, Nissen, Carl, Edmonds, Eric, Lyon, Roger, Chambers, Henry, Murnaghan, Lucas, Milewski, Matthew, Green, Daniel, Weiss, Jennifer, Wright, Rick, Carey, James, Polousky, John, Nepple, Jeffrey, Kocher, Mininder, Ganley, Theodore, Heyworth, BentonEnlace del recurso
Publicado 2021
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2490“…Results show that two-phase flow-based geometrical upscaling is a promising method for representing the effects of two-phase fault rock properties and complex 3D fault zone structure simultaneously.…”
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2491por Zhao, Li, Chen, Huaqian, Wu, Lin, Li, Zhengdong, Zhang, Ren, Zeng, Yan, Yang, Tao, Ruan, Hualing“…Moreover, KCNQ1OT1 regulated ROCK2 expression by binding to miR-93-5p. CONCLUSION: KCNQ1OT1 knockdown inhibited cell proliferation and fibrosis and induced apoptosis in DN by regulating miR-93-5p/ROCK2 axis, providing potential value for the treatment of DN. …”
Publicado 2021
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2492por Muralidharan, Priya, Hayes, Don, Fineman, Jeffrey R., Black, Stephen M., Mansour, Heidi M.“…Fasudil is a novel RhoA/Rho kinase (ROCK) inhibitor that has shown great potential in effectively treating pulmonary hypertension. …”
Publicado 2021
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2494por Wang, Jin, Zhou, Lei, Chen, Bingxin, Yu, Zhuwen, Zhang, Jianglei, Zhang, Zhe, Hu, Chenrui, Bai, Yanjin, Ruan, Xiaokang, Wang, Shengjia, Ouyang, Jun, Wu, Airong, Zhao, Xin“…Rescue experiments further confirmed the interaction between circCSPP1, miR-431, ROCK1 and ZEB1. Moreover, circCSPP1 promoted the expression level of ROCK1, cyclin D1, cyclin-dependent kinase 4, ZEB1 and Snail, and lowered the E-cadherin expression level. …”
Publicado 2022
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2495por Ying, Xinwang, Yu, Xiaolan, Zhu, Jintao, Li, Xuqing, Zheng, Yujun, Xie, Qingfeng, Wu, Qiaoyun, Li, Shengcun, Yue, Jingjing, Zhou, Ye, Zhou, Kecheng, Tu, Wenzhan, Jiang, Songhe“…Finally, TT effectively reduced the level of chondroitin sulfate proteoglycan (CSPG) surrounding the lesion and inhibited the NGR/RhoA/ROCK signaling pathway in neurons after SCI. Overall, we found that TT played a novel role in recovery from SCI by promoting axonal outgrowth associated with NGR/RhoA/ROCK signaling by inhibiting astrocyte activation after SCI.…”
Publicado 2022
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2496por Tonon, Federica, Cemazar, Maja, Kamensek, Urska, Zennaro, Cristina, Pozzato, Gabriele, Caserta, Sergio, Ascione, Flora, Grassi, Mario, Guido, Stefano, Ferrari, Cinzia, Cansolino, Laura, Trotta, Francesco, Kuzmanov, Biljana Grcar, Forte, Giancarlo, Martino, Fabiana, Perrone, Francesca, Bomben, Riccardo, Gattei, Valter, Elvassore, Nicola, Murano, Erminio, Truong, Nhung Hai, Olson, Michael, Farra, Rossella, Grassi, Gabriele, Dapas, Barbara“…Using multiple in vitro and in vivo models of HCC, we show for the first time that 5-Aza can impair HCC development via upregulation of miR-139-5p, which in turn downregulates the ROCK2/cyclin D1/E2F1/cyclin B1 pro-proliferative pathway and the ROCK2/MMP-2 pro-migratory pathway. …”
Publicado 2022
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2497por Wang, Ya, Lu, Yichen, Wan, Rongjun, Wang, Yang, Zhang, Chunfang, Li, Min, Deng, Pengbo, Cao, Liming, Hu, Chengping“…Inhibition of ROCK1 decreased MV secretion and partially reversed the PFN1-induced promotion of NSCLC metastasis. …”
Publicado 2022
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2498“…The expression levels of E-cadherin, N-cadherin, Vimentin and α-smooth muscle actin (α-SMA), proteins associated with epithelial-mesenchymal transition (EMT), in addition to RhoA, Rho-associated kinases (ROCK)1 and ROCK2, proteins related to RhoA/ROCK signaling, were also measured in SRA01/04 cells treated with HG and simvastatin, with or without U46619, using western blot analysis. …”
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2499por Giddings, Lesley-Ann, Kunstman, Kevin, Moumen, Bouziane, Asiama, Laurent, Green, Stefan, Delafont, Vincent, Brockley, Matthew, Samba-Louaka, Ascel“…While amoebae have been identified in acid rock drainage (ARD) systems, our understanding of their symbioses in these extreme environments is limited. …”
Publicado 2022
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2500por Gao, Feng, Wang, Xiao‐Chen, Luo, Zhi‐Dan, Hu, Guang‐Quan, Ma, Meng‐Qing, Liang, Yi, Xu, Bang‐Long, Lin, Xian‐He“…Luciferase reporter and RNA immunoprecipitation (RIP) assays verified the potential relationships between HOXA11‐AS or ROCK1 and miR‐515‐5p. The interactive roles between HOXA11‐AS and miR‐515‐5p and between miR‐515‐5p and ROCK1 were further characterized in ox‐LDL‐treated HUVECs. …”
Publicado 2022
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