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2501por Fan, Xinhui, Li, Xiaoxing, Liu, Huiruo, Xu, Feng, Ji, Xiaoping, Chen, Yuguo, Li, Chuanbao“…In vitro, ROCK1 was upregulated in HG-induced cardiomyocytes, and ROCK1 inhibition using Fasudil reversed the increased apoptosis, consistent with in vivo results. …”
Publicado 2022
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2502por Ma, Xiaoxiao, Wei, Lin, Hou, Dujie, Xu, Changgui, Man, Yong, Li, Wenlong, Wu, Piao“…They are a mixture generated from the source rocks in the middle and lower hydrocarbon supply combination. …”
Publicado 2022
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2503“…ABSTRACT: Many insect species overwinter in various rock shelters (cavities and crevices), but the microclimates of rock biotopes remain poorly understood. …”
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2504
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2505por Clemm, Thomas, Lunde, Lars-Kristian, Ulvestad, Bente, Færden, Karl, Nordby, Karl-Christian“…RESULTS: There was a significant exposure-response relationship on an individual level between HAV exposure from rock drills and VPT for 16 of 28 test frequencies. …”
Publicado 2022
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2506por Wei, Liufeng, Mo, Weiwei, Lan, Shanshan, Yang, Haiyan, Huang, Zhenxing, Liang, Xinghuan, Li, Li, Xian, Jing, Xie, Xuemei, Qin, Yingfen, Lin, Faquan, Luo, Zuojie“…Previous studies have shown that the RhoA/ROCK pathway plays an important role in the development of DR. …”
Publicado 2022
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2507“…This approach allowed to explore and quantify candidate rock density distributions along the GBT modelled profile in a computationally-efficient manner, and to test whether a reasonable fit can be found without structural modification of the geological model. …”
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2508por Long, Bei, Zhang, Qing, Duan, Tengfei, Song, Ting, Pei, Yong, Wang, Xianyou, Zhi, Chunyi, Wu, Xiongwei, Zhang, Qianyu, Wu, Yuping“…Remarkably, excellent electrochemical performances are maintained even at an ultrahigh mass loading of 15 mg cm(−2). Co‐UTBiOBr//MnO(2) “rocking chair” zinc‐ion battery exhibits a stable capacity of ≈130 mAh g(−1) at 0.2 A g(−1) during cyclic test and its flexible quasi‐solid‐state battery shows outstanding stability under various bending states. …”
Publicado 2022
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2509por Zhang, Yuanyuan, Wang, Shaojun, Guo, Sicong, Zhang, Xinzhong, Yang, Chuan, Su, Guangsheng, Wan, Jiye“…ROCK2 abated the influences of miR-942-5p in ox-LDL-stimulated HUVECs. …”
Publicado 2022
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2510
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2511por Lin, Xixi, Wang, Like, Lu, Xiaojie, Zhang, Yuanyuan, Zheng, Rongying, Chen, Ruijie, Zhang, Weixi“…Mechanistically, the effects that DC260126 alleviated obese asthma was correlated with the down-regulation of GTP-RhoA and Rho-associated coiled-coil-forming protein kinase 1 (ROCK1). Herein, we proved that targeting of GPR40 with its antagonist helped to mitigate multiple parameters of obese asthma effectively. …”
Publicado 2023
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2512“…Background: H(2)S (hydrogen sulfide) protects cerebral vasodilatation and endothelial cells against oxygen-glucose deprivation/reoxygenation injury via the inhibition of the RhoA-ROCK pathway and ROCK(2) expression. However, the inhibitory mechanism of H(2)S on ROCK(2) expression is still unclear. …”
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2513
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2514
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2515por Haas, Maximilian“…Analytical methods and schemes have been developed, tested and forecast the rocks to be encountered by proposed excavation machines and the beneficial uses for the excavated rock material.…”
Publicado 2022
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2516“…The arrival behavior of elastic waves in a naturally fractured rock is studied based on numerical simulations. We use the discrete fracture network method to represent the distribution of a natural fracture system and employ the displacement discontinuity method to compute the propagation of elastic waves across individual fractures. …”
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2517por Zhao, Guiying, Ren, Yali, Yan, Jie, Zhang, Tingrui, Lu, Peng, Lei, Jieting, Rao, Huanan, Kang, Xin, Cao, Zhixing, Peng, Fu, Peng, Cheng, Rao, Chaolong, Li, Yuzhi“…Recent studies indicated that ROCK2 plays a key role in smooth muscle contraction, and that ROCK2 inhibitors effectively control the symptoms of high intraocular pressure (IOP) in glaucoma patients. …”
Publicado 2023
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2518“…Metastable ZnO—Li(n−2)MeO(n−1) (Me = Sc(3+), Ti(4+), Ta(5+)) solid solutions with a rock-salt structure were synthesized through the solid-state reaction of ZnO with Li(n−2)Me(n+)O(n−1) (n = 3, 4, 5) complex oxides at 7.7 GPa and 1300–1500 K. …”
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2519“…To study fracture mechanisms and initiation of stress fields in the rock mass around a roadway subjected to cyclic stress, a series of loading and unloading tests were conducted on the rock mass around the roadway by using high-precision acoustic emission (AE) monitoring. …”
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2520por Liu, Pingping, Xiao, Zhenghui, Lu, Xiulan, Zhang, Xinping, Huang, Jiaotian, Li, Cheng“…SR1001 significantly reduced the expressions of GEF-H1, RhoA and ROCK1 in the model mice. The combination treatment with fasudil and SR1001 significantly inhibited the differentiation of Th17 cells, expressions of IL-17, GEF-H1, RhoA and ROCK1, which were more effective than each mono-treatment. …”
Publicado 2023
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