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  1. 3881
    “…Rho-kinase 1 (ROCK1) has been implicated in diverse metabolic functions throughout the body, with promising evidence identifying ROCK1 as a therapeutic target in diabetes and obesity. …”
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    Tissue-Specific Approaches Reveal Diverse Metabolic Functions of Rho-Kinase 1
  2. 3882
    “…CONCLUSION: This is the first study to show that ROCK1 gene and ROCK protein expressions may contribute to the development of MCL.…”
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    Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients
  3. 3883
    “…In order to investigate the support effect of the combination of FRP bolts and rebar bolts in the roadway, taking a coal mine as the background of the project, research and analysis of the engineering geological conditions of the mine and the layout of the mining roadway, stress analysis of the roadway peripheral rock, and put forward the combination of rebar and FRP bolts in the roadway peripheral rock support program. …”
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    Analysis of the impact of the combined use of rebar bolts and FRP bolts in the roadway enclosure
  4. 3884
    “…BACKGROUND: Rho-associated coiled-coil containing protein kinases 2 (ROCK2) is one of the best characterized targets for the small GTPase Rho. …”
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    Overexpression of Rho-Associated Coiled-Coil Containing Protein Kinase 2 Is Correlated with Clinical Progression and Poor Prognosis in Breast Cancer
  5. 3885
    por Liu, Kang, Li, Zhen, Wu, Tao, Ding, Suju
    Publicado 2011
    “…Rho kinase (ROCK) is a well-known downstream effector of Rho and plays an important role in various physiopathological processes. …”
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    Role of Rho Kinase in Microvascular Damage Following Cerebral Ischemia Reperfusion in Rats
  6. 3886
    “…Massive waste rock wool was generated globally and it caused substantial environmental issues such as landfill and leaching. …”
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    Waste Mineral Wool and Its Opportunities—A Review
  7. 3887
    “…Rho-associated coiled-coil kinase (ROCK) is a major downstream effector of the small GTPase RhoA. …”
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    Novel Insights into the Roles of Rho Kinase in Cancer
  8. 3888
    “…BACKGROUND: Rho-associated coiled-coil containing protein kinase (Rho-kinase/ROCK) is involved in various cellular functions including cell proliferation, and is generally considered to be oncogenic, while some studies show that ROCK functions as a negative regulator of cancer progression. …”
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    Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells
  9. 3889
    “…BACKGROUND: The serine/threonine protein kinases ROCK1 and 2 are key RhoA-mediated regulators of cell shape and cytoskeletal dynamics. …”
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    Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth
  10. 3890
    “…We and others have previously demonstrated that inhibition of ROCK blocks endoderm differentiation in embryonal carcinoma stem cells, however, the effect of ROCK inhibition on mesoderm and ectoderm specification has not been fully examined. …”
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    Inhibition of Rho Kinase Regulates Specification of Early Differentiation Events in P19 Embryonal Carcinoma Stem Cells
  11. 3891
    “…Live-imaging of keratinocytes cultured with ROCK inhibitors show that the effect of ROCK inhibition on cellular proliferation is immediate and ROCK inhibited cells proliferate rapidly without differentiation or stratification. …”
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    The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional
  12. 3892
    “…Rho-associated coiled-coil-forming protein kinase (ROCK) consists as two isoforms, ROCK1 and ROCK2, and both are playing critical roles in many cellular responses to injury. …”
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    Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair
  13. 3893
    por Si, Xuefeng, Peng, Kang, Luo, Song
    Publicado 2022
    “…The test results show that the failure process at different depths can be divided into four periods: the calm period, the particle ejection period, the rock fragment exfoliation period, and the rock bursting period. …”
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    Experimental Investigation on the Influence of Depth on Rockburst Characteristics in Circular Tunnels
  14. 3894
    “…Using mice with hematopoietic-specific ROCK1 deficiency, we investigated the effects of ROCK1 deficiency on NETosis, and its involvement in UVB-induced skin inflammation. …”
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    Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation
  15. 3895
    “…It has been reported that leukocyte ROCK activity is elevated in patients after ischemic stroke, but it is unclear whether leukocyte ROCK activity is associated with clinical outcomes following acute stroke events. …”
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    The Prognostic Values of Leukocyte Rho Kinase Activity in Acute Ischemic Stroke
  16. 3896
    “…BACKGROUND: Activation of Rho, one of the small GTPases, and its major downstream target Rho-kinase (ROCK) promotes the development and metastasis of cancer. …”
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    The Rho-kinase inhibitor HA-1077 suppresses proliferation/migration and induces apoptosis of urothelial cancer cells
  17. 3897
    “…Here, we have explored different approaches to genetically engineering cambial activity in poplar plants by the ectopic expression of a cytokinin biosynthesis gene with enhanced activity (named ROCK4) or of a gene encoding a constitutively active cytokinin receptor variant (ROCK3). …”
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    A Constitutively Active Cytokinin Receptor Variant Increases Cambial Activity and Stem Growth in Poplar
  18. 3898
    “…Modulation of IL-17 and ROCK proteins may represent a promising approach for the treatment of this disease. …”
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    Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma
  19. 3899
    por Singh, Kirti, Singh, Arshi
    Publicado 2023
    “…AIM: This review summarizes current data on Rho-kinase (ROCK) inhibitors use in ocular diseases, primarily glaucoma. …”
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    Rho-kinase Inhibitors in Ocular Diseases: A Translational Research Journey
  20. 3900
    “…However, whether ROCK1 plays a role in liver inflammation and fibrosis during NASH is unclear. …”
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    Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis
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