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  1. 3921
    por Sun, Jichao
    Publicado 2019
    “…The fissure patency of a rock mass is an important factor contributing towards the fluid production efficiency. …”
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    Hard particle force in a soft fracture
  2. 3922
    “…The Gunu Site Complex, in the remote Mitchell River region of the northwest Kimberley, is one of many local expressions of the Kimberley rock art sequence. Here we report excavations at two sites in this complex: Gunu Rock, a sand sheet adjacent to rock art panels; and Gunu Cave, a floor deposit within an extensive rockshelter. …”
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    Archaeology and art in context: Excavations at the Gunu Site Complex, Northwest Kimberley, Western Australia
  3. 3923
    “…Fasudil, a clinically approved ROCK inhibitor, improved retinal perfusion and reduced edema in this model, indicating that ROCK inhibition could be a promising new therapeutic approach for the treatment of diabetic retinopathy. …”
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    Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy
  4. 3924
    “…Our data identify ROCK1 as a key regulator of leptin action on energy homeostasis.…”
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    Rho-kinase Regulates Energy Balance by Targeting Hypothalamic Leptin Receptor Signaling
  5. 3925
    “…PURPOSE: Does perioperative use of Rho-Kinase (ROCK) inhibitors have beneficial effect on corneal endothelial cells after phacoemulsification? …”
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    Perioperative Use of Rho-Kinase Inhibitors has Beneficial Effect on Corneal Endothelium after Phacoemulsification
  6. 3926
    por Fan, Ling, Wang, Chengbo, Hu, Di
    Publicado 2023
    “…Rock masses are inherently heterogeneous, with numerous fractures that significantly affect their mechanical properties, fracture characteristics, and acoustic emission features due to the interactions between fractures or between fractures and the rock mass. …”
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    Experimental Study on Acoustic Emission Characteristics of Uniaxial Compression of MICP-Filled Sandstone
  7. 3927
    “…Rho‐associated coiled‐coil kinase 1 (ROCK1) is proposed to be implicated in Aβ suppression; however, the role for ROCK1 in amyloidogenic metabolism of amyloid precursor protein (APP) to produce Aβ was unknown. …”
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    Rho‐associated coiled‐coil kinase 1 activation mediates amyloid precursor protein site‐specific Ser655 phosphorylation and triggers amyloid pathology
  8. 3928
    “…To characterize the role of apoptotic cell contraction, ROCK1 was rendered caspase non-cleavable (ROCK1nc) by mutating aspartate 1113, which revealed that ROCK1 cleavage was necessary for forceful contraction and membrane blebbing. …”
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    Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression
  9. 3929
    “…The issue of monitoring and early warning of rock instability has received increasing critical attention in the study of rock engineering. …”
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    Application of Two Novel Acoustic Emission Parameters on Identifying the Instability of Granite
  10. 3930
    “…BACKGROUND: Rho kinases (ROCKs) mediate cell contraction, local adhesion, and cell motility, which are considered to be important in cell differentiation. …”
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    Rho Kinases Regulate the Renewal and Neural Differentiation of Embryonic Stem Cells in a Cell Plating Density–Dependent Manner
  11. 3931
    “…However, there is currently no unified regulation on the selection of rock sample size in tight oil reservoir imbibition evaluation experiments, resulting in great differences in reservoir imbibition oil production capacity obtained from rock samples of different sizes, which brings great challenges to the efficient development of tight oil reservoirs. …”
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    The Law and Mechanism of the Sample Size Effect of Imbibition Oil Recovery of Tight Sedimentary Tuff
  12. 3932
    “…We also demonstrated that serum stimulation induced phosphorylation (activation) of ZIPK, which was inhibited by ROCK and ZIPK down-regulation and inhibition. Finally, basal phosphorylation of LC(20) in the absence of serum stimulation was unaffected by MLCK, ROCK or ZIPK knockdown or inhibition. …”
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    Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells
  13. 3933
    “…Also, ROCK activity was determined in T. cruzi-infected, BALB/c mice hearts. …”
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    Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition
  14. 3934
    “…Expression of ROCK/Rho-kinase mRNA was significantly increased and up-regulated in the spastic coronary artery in a porcine model, and a specific inhibitor of ROCK/Rho-kinase inhibited coronary artery spasm in humans. …”
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    Rho-Associated Kinase 2 Polymorphism in Patients With Vasospastic Angina
  15. 3935
    “…But the function and mechanism it works on in osteosarcoma proliferation and metastasis mediated by Rho associated coiled-coil containing protein kinase 1 (ROCK1) and Rho associated coiled-coil containing protein kinase 2 (ROCK2) remain unclear. …”
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    Long non-coding RNA MALAT1 for promoting metastasis and proliferation by acting as a ceRNA of miR-144-3p in osteosarcoma cells
  16. 3936
    “…Litter size had no influence. Lep, LepR, RhoA, ROCK1, ROCK2 protein and/or mRNA were localized in the myometrium and endometrium. …”
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    Implications of the RhoA/Rho associated kinase pathway and leptin in primary uterine inertia in the dog
  17. 3937
    “…Firstly, the triaxial pre-peak loading and unloading tests on the prepared samples are conducted on the intact rock samples using the TAW-200 rock mechanics test system. …”
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    Experimental study on uniaxial creep characteristics of sandstone with pre-peak unloading damage
  18. 3938
    “…Manipulation of AJs using a calcium-switch assay and cadherin-blocking antibodies indicates direct recruitment of ROCK1 to newly forming junctions. Importantly, we find that p120 links ROCK1 to the cadherin complex, as ROCK1 coimmunoprecipitates with wild-type but not p120-uncoupled E-cadherin. …”
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    Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin
  19. 3939
    “…The lowest virus copy numbers were observed in rock dove. The virus infectivity was significantly reduced in the BALB/3T3 cells expressing rock dove and jungle crow Mx. …”
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    Characterization of Myxovirus resistance protein in birds showing different susceptibilities to highly pathogenic influenza virus
  20. 3940
    “…Here, the expression level of ROCK1 is higher in LSCC tissues than non-tumor tissues, and the expression level of ROCK1 is positively correlated with advanced stage and poor survival prognosis. …”
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    Rho-associated kinase1 promotes laryngeal squamous cell carcinoma tumorigenesis and progression via the FAK signaling pathway
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