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  1. 4321
    “…In contrast to the closely related ROCK1 and ROCK2 kinases that are regulated by the RhoA and RhoC GTPases, there is relatively little information about the CDC42-regulated MRCKα, MRCKβ and MRCKγ members of the AGC (PKA, PKG and PKC) kinase family. …”
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    The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer
  2. 4322
    por Elci, Hakan, Turk, Necdet
    Publicado 2014
    “…The Block Quality Designation (BQD) ratio method proposed by the authors has been found to have given in the same order of the rock block volume to the volumetric joint count (J (v)) method. …”
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    Block Volume Estimation from the Discontinuity Spacing Measurements of Mesozoic Limestone Quarries, Karaburun Peninsula, Turkey
  3. 4323
    “…The proposed model is useful for rock mechanical parameters determination and instability investigation of rock slopes.…”
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    Displacement Back Analysis for a High Slope of the Dagangshan Hydroelectric Power Station Based on BP Neural Network and Particle Swarm Optimization
  4. 4324
    “…However, there are nonlinear relations between equivalent cohesive strength and Geological Strength Index (GSI), the uniaxial compressive strength of intact rock σ (ci), and the parameter of intact rock m (i). …”
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    Slope Stability Analysis Using Limit Equilibrium Method in Nonlinear Criterion
  5. 4325
    “…Our results indicate that Rock is the major downstream effector of Shroom3 in the process of neural tube morphogenesis. …”
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    The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice
  6. 4326
    “…Resistance mechanisms of rho-associated kinase (ROCK) inhibitors are associated with the enhanced expression of cyclooxygenase-2 (COX-2). …”
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    Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
  7. 4327
    “…The Rho-associated coiled-coil containing kinases (ROCK) were first identified as effectors of the small GTPase RhoA, hence their nomenclature. …”
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    Made to measure – keeping Rho kinase at a distance
  8. 4328
    “…Our study shows that even small LGM ice caps can dominate present-day rock uplift in tectonically active regions.…”
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    Glacial isostatic uplift of the European Alps
  9. 4329
    por Cheng, Xinqi, Zhang, Jie, Chen, Zhiwu
    Publicado 2017
    “…TFR treatment attenuated the upregulation of these factors, downregulated UTR expression, and markedly diminished the expression of RhoA and ROCK1/2. These results suggested that TFR could improve cardiac function and ameliorate ventricular remodeling through blocking UTR-mediated activation of RhoA-ROCK pathways in myocardial infarction rats.…”
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    Effects of Total Flavone from Rhododendron simsii Planch. Flower on Postischemic Cardiac Dysfunction and Cardiac Remodeling in Rats
  10. 4330
    por Li, Chengwu, Ai, Dihao
    Publicado 2017
    “…In the coal mining process, the destabilization of loaded coal mass is a prerequisite for coal and rock dynamic disaster, and surface cracks of the coal and rock mass are important indicators, reflecting the current state of the coal body. …”
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    Automatic crack detection method for loaded coal in vibration failure process
  11. 4331
    “…Thus, we conclude that Rho A/ROCK1/LIMK2/Cofilin signaling mediates actin microfilament formation in MG63 cells upon EGFR activation. …”
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    Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell Migration
  12. 4332
    “…Disturbed epithelial polarity and cystogenesis upon DDR1 inhibition was caused by excess ROCK (rho-associated, coiled-coil-containing protein kinase)-driven actomyosin contractility, and pharmacological inhibition of ROCK was sufficient to correct these defects. …”
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    Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility
  13. 4333
    “…The rockburst intensity grade of Engineering Rock Mass is predicted by rock burst intensity level variable and the interval. …”
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    A prediction model on rockburst intensity grade based on variable weight and matter-element extension
  14. 4334
    “…However, few people have researched the automatic detection method for steel arches installed on a complex rock surface. This paper presents a novel algorithm to extract tunnel steel arches. …”
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    Automatic Tunnel Steel Arches Extraction Algorithm Based on 3D LiDAR Point Cloud
  15. 4335
    por Dong, Longjun, Zhang, Yihan, Ma, Ju
    Publicado 2020
    “…To explore the potential precursors of rock instability, it is necessary to clarify the mechanism of micro-crack from fracturing to failure, which involves the evolution of fracture size, orientation, source model, and their relationships to the loading. …”
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    Micro-Crack Mechanism in the Fracture Evolution of Saturated Granite and Enlightenment to the Precursors of Instability
  16. 4336
    “…We showed this HC rearrangement, redefined as two processes named Rock and Roll, is required for positional acquisition of HCs. …”
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    Emx2 regulates hair cell rearrangement but not positional identity within neuromasts
  17. 4337
    “…Bacteria isolated from dryland rocks are typical of xeric environments and are described as being involved in rock weathering processes. …”
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    Living Lithic and Sublithic Bacterial Communities in Namibian Drylands
  18. 4338
    “…During the loading process, the piezoelectric effect and compressive strength are key factors in the gathering of free charges on rock tips. During rupture, the rock tip retains a large number of charges, forming a ″point-surface″ effect, which triggers an electron avalanche accompanied by an orange-yellow spark lasting over 22 ms, far exceeding the ionization energy and ignition induction period of methane–air mixtures. …”
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    Piezoelectric Effect and Ignition Characteristics of Coal Mine Gob Roof Collapse
  19. 4339
    “…In this context, solutions using thermal energy storage through rock start to emerge, due to its natural benefits, when compared to more polluting alternatives. …”
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    Physical and Thermal Properties Analysis of Hematite for Thermal Heat Storage
  20. 4340
    “…Pharmacological inhibition of the Ser/Thr kinase ROCK, an RhoA effector, induces neuritogenesis in unchallenged PC12 cells, and potentiates the effect of androgens and NGF, confirming the role of RhoA/ROCK axis in the neuritogenesis induced by androgen and NGF, through the phosphorylation of Akt. …”
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    Androgens and NGF Mediate the Neurite-Outgrowth through Inactivation of RhoA
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