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  1. 4361
    “…Moreover, long-term inhibition of protein prenylation results in basal hyper activation of RhoA/Rock signaling that is antagonized by a specific Rock inhibitor or an activation of cAMP signaling. …”
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    Inhibition of Protein Prenylation of GTPases Alters Endothelial Barrier Function
  2. 4362
    “…The subject of rock–fluid interaction is important in cases where flow through porous media is occurring. …”
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    Investigating the Fluid–Solid Interaction of Acid Nonionic Nanoemulsion with Carbonate Porous Media
  3. 4363
    “…[Image: see text] Asphaltene adsorption and deposition onto rock surfaces are predominantly the cause of wettability and permeability alterations which result in well productivity losses. …”
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    Impact of Iron Minerals in Promoting Wettability Alterations in Reservoir Formations
  4. 4364
    “…Secondly, we investigated the role of RhoA-ROCK pathway in ARVC pathogenesis, and thirdly we analyzed the interplay between Wnt and RhoA-ROCK pathways in the context of the ARVC phenotype. …”
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    Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling
  5. 4365
    “…The present study was conducted in two jhum fallows (FL-10 and FL-15) to understand the response of fallow length and applications of indigenous soil microbes and rock phosphate on the levels of soil fertility and crop productivity. …”
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    Soil fertility and rice productivity in shifting cultivation: impact of fallow lengths and soil amendments in Lengpui, Mizoram northeast India
  6. 4366
    por Zhang, Jianzhong, Gao, Tianrun
    Publicado 2021
    “…The theory of stress and strain of rock mechanics also shows that the rock compressibility is determined by Young’s modulus, Poisson’s ratio, and porosity and has no connection with the formation pressure. …”
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    Compressibility of Abnormal Pressure Gas Reservoirs and Its Effect on Reserves
  7. 4367
    “…The dataset includes geographical coordinates, lithological logs of drill holes, rock and mineral chemistry data, and pseudosections. …”
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    Dataset to evaluate the geology, metamorphic conditions and pseudosection modeling of the Luswishi Dome, Copperbelt, Zambia
  8. 4368
    “…The retarding performance and acid–rock reaction rates of AR-1 and AR-2 were evaluated, and the experimental results indicated that AR-2 had a better retarding performance than AR-1, and the acid–rock reaction rate of AR-1 was higher than AR-2. …”
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    The effect of hydrophobic chains on retarding performance of retarding acids
  9. 4369
    “…The high shale recovery rate demonstrated its strong shale inhibition performance. The rock treated by catechol-chitosan biopolymer had higher tension shear strength and uniaxial compression strength than others, which indicates that it can effectively strengthen the rock and bind loose minerals in micro-pore and micro-fracture of rock samples. …”
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    Wellbore Stability through Novel Catechol-Chitosan Biopolymer Encapsulator-Based Drilling Mud
  10. 4370
    “…Due to the long-term coupling effect of a train load and groundwater, the surrounding rock at the tunnel bottom will soften in a certain range and the mechanical parameters of the surrounding rock will decrease, causing the uneven distribution of the confining pressure at the tunnel bottom and affecting the base concrete structure service life. …”
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    Dynamic Response and Service Life of Tunnel Bottom Structure Considering Hydro-Mechanical Coupling Effect under the Condition of Bedrock Softening
  11. 4371
    “…To understand the influence of slurry mass concentration, waste rock content, and cement-sand ratio on the cemented backfill strength and fluidity, influential factors were determined by range analysis of orthogonal proportion experiments. …”
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    Multi-Response Robust Parameter Optimization of Cemented Backfill Proportion with Ultra-Fine Tailings
  12. 4372
    “…The pit is located under an unstable rock mass and landslide body; its base lithology is mudstone. …”
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    Numerical and Field Measurement Investigation on Foundation Pit Excavation Blasting of Anchor in Suspension Bridge
  13. 4373
    “…LPA induces phosphorylation of MYPT1 through ROCK (T853) and PKC/ERK (S507), which is majorly driven by LPAR1. …”
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    The lysophosphatidic acid-regulated signal transduction network in ovarian cancer cells and its role in actomyosin dynamics, cell migration and entosis
  14. 4374
    “…These effects involve the activation of the small GTPase RhoA/ROCK signaling pathways, which negatively modulate growth cone cytoskeleton, similarly to well stablished inhibitors of axon regeneration described so far. …”
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    Blockade of Rho-associated kinase prevents inhibition of axon regeneration of peripheral nerves induced by anti-ganglioside antibodies
  15. 4375
    “…However, complete restoration of cortical F-actin required incubation with the ROCK inhibitor Y27632 in combination with ZEB1/2 knockdown. …”
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    Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
  16. 4376
    “…CONCLUSIONS: This study demonstrated that arecoline induces anoikis of HA22T/VGH cells involving inhibition of STAT3 and increased RhoA/Rock activation and that the STAT3 and RhoA/Rock signaling pathways are connected.…”
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    Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation
  17. 4377
    “…The Rho-associated protein kinase (ROCK) inhibitor, Y-27632, significantly increased cell survival rate, adhesion, and migration in numerous types of cells, including stem cells, suggesting a common feature of the ROCK-mediated apoptotic pathway that may also exist in human CSCs. …”
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    Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells
  18. 4378
    “…Renal fibrosis is the major cause of chronic kidney disease, and the Rho/Rho-associated coiled-coil kinase (ROCK) signaling cascade is involved in the renal fibrotic processes. …”
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    Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction
  19. 4379
    “…The geochemical compositions of subsurface fluids in the ophiolite are highly variable, reflecting differences in host rock composition and the extent of fluid-rock interaction. …”
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    Geological and Geochemical Controls on Subsurface Microbial Life in the Samail Ophiolite, Oman
  20. 4380
    “…Among these inhibitors, the ROCK inhibitor was the most disruptive to the actin stress fibers, whereas ERK inhibition showed the least disruption. …”
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    TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways
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