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4381por Nguyen Dinh Cat, Aurelie, Callera, Glaucia E., Friederich-Persson, Malou, Sanchez, Ana, Dulak-Lis, Maria Gabriela, Tsiropoulou, Sofia, Montezano, Augusto C., He, Ying, Briones, Ana M., Jaisser, Frederic, Touyz, Rhian M.“…Therefore, we investigated the role of Rho kinase (ROCK) in aldosterone/MR signaling and vascular dysfunction in a model of diabetes. …”
Publicado 2018
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4382por Yan, Lu-Lu, Zhang, Wei-Yang, Wei, Xiao-Hong, Yan, Li, Pan, Chun-Shui, Yu, Yang, Fan, Jing-Yu, Liu, Yu-Ying, Zhou, Hua, Han, Jing-Yan, Yao, Xin-Sheng“…Conclusions: Treatment with GLXB effectively protects myocardial structure and function from I/R challenge, possibly via regulating energy metabolism involving inactivation of RhoA/ROCK signaling pathway.…”
Publicado 2018
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4383“…In diabetic antrum muscles, MYLK and MYL9 expression was unchanged, but ROCK2, CPI-17, and PP1δ expression was decreased. …”
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4384por Yuan, Jie, Zhang, Fan, Hallahan, Dennis, Zhang, Zhen, He, Liming, Wu, Ling-Gang, You, Meng, Yang, Qin“…Moreover, reprogramming treatment with ROCK-mTOR inhibitors prevented GBM local recurrence in mice. …”
Publicado 2018
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4385por Ibrahim, Diah Gemala, Ko, Ji‐Ae, Iwata, Wakana, Okumichi, Hideaki, Kiuchi, Yoshiaki“…We have now examined the effect of Y‐27632, a Rho‐associated protein kinase (ROCK) inhibitor, on postsurgical scarring formation in human Tenon fibroblasts (HTFs). …”
Publicado 2019
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4386por Clemm, Thomas, Færden, Karl, Ulvestad, Bente, Lunde, Lars-Kristian, Nordby, Karl-Christian“…RESULTS: The participants were either exposed to rock drills (n=33), impact wrenches (n=52) or none of these tools (n=19). …”
Publicado 2020
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4387por Tukur, Hammed A., Aljumaah, Riyadh S., Swelum, Ayman Abdel-Aziz, Alowaimer, Abdullah N., Abdelrahman, Mutassim, Saadeldin, Islam M.“…This positive result suggests ROCK inhibitor as a potential candidate molecule to exploit in the control of oocyte meiotic maturation. …”
Publicado 2020
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4388por Guerin, Antoine, Jaboyedoff, Michel, Collins, Brian D., Stock, Greg M., Derron, Marc-Henri, Abellán, Antonio, Matasci, Battista“…A growing body of research indicates that rock slope failures, particularly from exfoliating cliffs, are promoted by rock deformations induced by daily temperature cycles. …”
Publicado 2020
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4389“…In addition, the expression levels of phosphorylated (p)-myosin light chain (MLC), MLC kinase (MLCK) and Rho-associated kinase (ROCK) were significantly increased in the D-GalN/LPS-induced mice compared with those in the control mice, whereas the subsequent inhibition of MLCK or ROCK significantly reduced p-MLC expression levels. …”
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4390por Tanaka, Takeshi, Mori, Masahiko, Sekino, Motohiro, Higashijima, Ushio, Takaki, Masahiro, Yamashita, Yoshiro, Kakiuchi, Satoshi, Tashiro, Masato, Morimoto, Konosuke, Tasaki, Osamu, Izumikawa, Koichi“…In the experiment, serotonin increased the permeability of ECs, which was inhibited by the ROCK inhibitor (p < 0.001). Serotonin increases vascular permeability of ECs via ROCK signaling. …”
Publicado 2021
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4391por Zhang, Zhenzhen, Zeng, Jing, Li, Yang, Liao, Qing, Huang, Dongdong, Zou, Yucong, Liu, Gang“…A dual-luciferase assay verified that miR-103 binds to the 3'-untranslated region end of Rock1 mRNA, thus negatively regulating the activity of Rock1 and affecting pathological ossification during AS. …”
Publicado 2021
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4392“…According to the actual field test parameters of coal seam #3 in the Sanyuan coal mine, D(lim) = 0.81 ~ 1.0 was the coal rock crushing area, D(lim) = 0.19 ~ 0.81 was the coal rock crack area, and D(lim) = 0 ~ 0.19 was the coal rock disturbance area. …”
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4393por Fujii, Taichi, Ueno, Kaoru, Shirako, Tomoyasu, Nakamura, Masatoshi, Minami, Motoyasu“…DNA metabarcoding was employed to identify plant-derived food resources for the Japanese rock ptarmigan (Lagopus muta japonica), which is registered as a natural living monument in Japan, in the Northern Japanese Alps in Toyama Prefecture, Japan, in July to October, 2015–2018. …”
Publicado 2022
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4394por Song, Shuang, Zhang, Tianjun, Pan, Hongyu, Pang, Mingkun, Zhang, Xiufeng, Zhang, Lei, Bao, Ruoyu“…In order to study the relationship between the lost particles of different graded rock samples and the pore structure of the subsidence column filling, experiments were designed and the changes of the seepage parameters of graded rock samples during the particle migration process under different permeable water pressures P and axial loads F were determined. …”
Publicado 2022
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4395“…In this study, the principles of rock pyrolysis and gas chromatographic analyses in geochemical logging are studied. …”
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4396por Ambrosio, M“….) +/- 11 (syst.) GeV in the rock depth range 3000-6500 hg/cm^2. The results are in agreement with calculations of the energy loss of muons in the rock above the detector.…”
Publicado 1998
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4397“…The growth of microbial biofilms and various biomineralization phenomena can lead to the formation of stable layers and veneers on rocks known as ‘rock varnishes’ that can stabilize surfaces and protect from further weathering. …”
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4398“…The whole rock geochemistry is made publicity available to enable significant analyzes.…”
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4399“…The symposium is organized by Tsinghua University, the International Association for Computer Methods and Advances in Geomechanics (IACMAG), the Committee of Numerical and Physical Modeling of Rock Mass, Chinese Society for Rock Mechanics and Engineering, and the Committee of Constitutive Relations and Strength Theory, China Institution of Soil Mechanics and Geotechnical Engineering, China Civil Engineering Society. …”
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4400“…In particular, when the tensile strength of rock is lower, the fracture initiation may occur within the rock mass rather than on the wellbore wall. …”
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