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  1. 4461
    “…However, even at this higher concentration a Rho-dependent axon elongating activity could be recovered upon removal of ROCK activity using Y-27632. SDF-1α–induced axon elongating activity under ROCK inhibition was replicated by the dominant-active form of the mammalian homologue of the Drosophila gene Diaphanous (mDia)1 and counteracted by its dominant-negative form. …”
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    Control of axon elongation via an SDF-1α/Rho/mDia pathway in cultured cerebellar granule neurons
  2. 4462
    “…Through interactions with Src homology 3 domain containing proteins involved in CME, OPHN1 is concentrated to endocytic sites where it down-regulates the RhoA/ROCK signaling pathway and represses the inhibitory function of ROCK on endocytosis. …”
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    Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation
  3. 4463
    “…Finally, in vivo ROCK inhibition significantly increased phosphorylated p53 levels and neurofilaments in axons, and axonal bundle size in npc1−/− mice. …”
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    Cholesterol Perturbation in Mice Results in p53 Degradation and Axonal Pathology through p38 MAPK and Mdm2 Activation
  4. 4464
    “…Both the Wood pigeon (Columba palumbus) and the Rock pigeon (Columba livia) have long breeding seasons and lay two-egg clutches. …”
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    An adaptive annual rhythm in the sex of first pigeon eggs
  5. 4465
    “…The gas flow was ~250 ml min(-1). Rock powders were melted and homogenized for microchemcial analyses. …”
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    Description of an aerodynamic levitation apparatus with applications in Earth sciences
  6. 4466
    “…The cell-permeable Rho inhibitor C3 transferase inhibited SP-induced PAK phosphorylation, but the ROCK inhibitor Y27632 had no effect on PAK phosphorylation, suggesting that Rho activates PAK in a ROCK-independent manner. …”
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    Substance P Induces Rapid and Transient Membrane Blebbing in U373MG Cells in a p21-Activated Kinase-Dependent Manner
  7. 4467
    “…However, p53 abnormality impaired centrosome clustering and lead to multipolar mitosis in tetraploid cells by modulating the RhoA/ROCK signaling pathway.…”
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    p53 Dependent Centrosome Clustering Prevents Multipolar Mitosis in Tetraploid Cells
  8. 4468
    “…For many years, small-scale Trentepohlia coverage had been found on the rocks of some glacier valleys on the northern slopes of Mt. …”
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    Massive Trentepohlia-Bloom in a Glacier Valley of Mt. Gongga, China, and a New Variety of Trentepohlia (Chlorophyta)
  9. 4469
    “…Our results suggest that Mcf2l-RhoA-ROCK signaling pathway mediates IL1RAPL1-dependent formation and stabilization of glutamatergic synapses of cortical neurons.…”
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    IL1RAPL1 Associated with Mental Retardation and Autism Regulates the Formation and Stabilization of Glutamatergic Synapses of Cortical Neurons through RhoA Signaling Pathway
  10. 4470
    “…No statistically significant difference in mean BFS scores was found between the EQUIA system and ChemFil Rock at 30 s and 60 s. The mean BFS value was statistically significantly higher for the EQUIA system and ChemFil Rock than for Fuji 9 Gold Label and Ketac Molar Easymix at all exposure times.…”
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    Biaxial Flexural Strength of High-Viscosity Glass-Ionomer Cements Heat-Cured with an LED Lamp during Setting
  11. 4471
    “…Several signalling inhibitors interfered with progesterone-induced FAK activation, including progesterone receptor (PR) antagonist ORG 31710, specific c-Src kinase inhibitor PP2, phosphatidylinosital-3 kinase (PI3K) inhibitor wortmannin as well as ρ-associated kinase (ROCK-2) inhibitor Y27632. It suggested that PR, c-Src, PI3K and ROCK-2 are implicated in this action. …”
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    Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase
  12. 4472
    “…[Image: see text] The myosin light chain phosphatase (MLCP) is a cytoskeleton-associated protein phosphatase-1 (PP1) holoenzyme and a RhoA/ROCK effector, regulating cytoskeletal reorganization. …”
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    Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1
  13. 4473
    “…The wild ancestor of the Feral Pigeon, the Rock Dove, is a species of rocky habitats, nesting typically on cliff ledges and at the entrance to large caves. …”
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    The earliest pigeon fanciers
  14. 4474
    “…Large-pressure gradients cause influx and heating of water within the pipe with horizontal convergent flow in the host rock and along pipe margins, and upward flow within the pipe centre. …”
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    Hydrothermal alteration of kimberlite by convective flows of external water
  15. 4475
    “…Barometric pumping of gas through explosion-fractured rock is investigated using a new sequentially-coupled hydrodynamic rock damage/gas transport model. …”
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    Radionuclide Gas Transport through Nuclear Explosion-Generated Fracture Networks
  16. 4476
    “…MSCs differentiate into myofibroblasts when RhoA/ROCK is turned on, endothelial cells when turned off. …”
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    RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF–VEGF complex in extracellular matrix
  17. 4477
    “…We also showed that CEC engraftment is impaired by limited substrate adhesion, which is due to actomyosin contraction induced by dissociation-induced activation of ROCK/MLC signaling. Inclusion of a ROCK inhibitor improves efficiency of engraftment of CECs and enables cell-based therapy for treating corneal endothelial dysfunction as a clinically relevant therapy.…”
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    Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction
  18. 4478
    “…Of the 1289 collected larvae from the rock pools, seven belonged to the Anopheles Claviger Complex. …”
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    Anopheles (Anopheles) petragnani Del Vecchio 1939—a new mosquito species for Germany
  19. 4479
    “…Four conditions including and excluding HA + ROCK and its effect on early attachment rates and proliferation was studied on forty-eight corneas. …”
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    Human Corneal Endothelial Cell Cultivation From Old Donor Corneas With Forced Attachment
  20. 4480
    “…LPA stimulated the activation of ROCK2 and p38 MAPK; and inhibition of ROCK2 or p38 MAPK suppressed LPA-induced IL-17 expression. …”
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    Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice
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