“…Moreover, we identified that Linc00205 was able to directly bind to miR-154-3p, thus isolating miR-154-3p from its target Rho-associated coiled-coil Kinase 1 (ROCK1). Further cellular behavioral experiments elucidated that the miR-154-3p inhibitor and ROCK1 overexpression were able to reverse the effect of downregulated Linc00205 on proliferation, migration, invasion, and apoptosis of HB cells by rescue assays via mitogen-activated protein kinase (MAPK) signaling. …”
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“…The impact-induced fragmentation of rock is widely and frequently encountered when natural hazards occur in mountainous areas. …”
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“…PURPOSE: To explore the influence of milk fat globule-EGF factor 8 protein (MFGE8) on blunt abdominal injury in Sprague Dawley (SD) rats through the RhoA/ROCK signaling pathway. METHODS: The blunt abdominal injury model was generated in SD rats. …”
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“…RESULTS: Cells from the condylar fibrocartilage of the TMJ were successfully immortalized by ROCK inhibitor, retaining a consistent cuboidal cell morphology and the expression of several cell markers of polymorphic cell fate. …”
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“…[Image: see text] With the extension of mines to deep mining, horizontal stress has become an important factor in the stability of the roadway surrounding rock, and the influence of horizontal stress on the structure of a layered roof is more complex. …”
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“…Acoustic emission (AE) is often accompanied by the propagation of internal microcracks in loaded rock samples, and it essentially reflects microinstability phenomena driven by energy redistribution under stress. …”
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“…Our findings indicated that the increased expression of Runx2 in the cells residing on the bTi nanopillars compared to the flat Ti is highly dependent on the activity of FAK and ROCK. A mechanotransduction pathway is then postulated in which the FAK-dependent adhesion of cells to the extreme topography of the surface is in close relation with ROCK to increase the endogenous forces within the cells, eventually determining the cell shape and area. …”
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“…We present a novel approach to model hydro-chemo-mechanical responses in rock formations subject to fracture propagation within chemically active rock formations. …”
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“…It has been observed that nanoparticles can change rock wettability, increase polymer viscosity, and decrease polymer retention in carbonate rock. …”
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“…Prior to the course modules on rock classification, students self-rated their knowledge, took a prior knowledge test, classified rock exemplars by completing study or retrieval practice trials, and made study order choices. …”
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“…Y-27632 inhibits Rho-associated coiled-coil-containing protein kinase (ROCK) signaling, which is involved in various embryonic developmental processes, including angiogenesis, by controlling actin cytoskeleton assembly and cell contractility. …”
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“…Snow accumulated beyond a thin layer, however, is counterproductive, interfering with rock insolation, snow melting, and photosynthetic access to light. …”
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“…These data are related to the research article entitled “Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2” Jerrell and Parekh, 2016.…”
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“…Q-slope is based on over 500 rock slope case studies from mines, road and rail cuttings hosted in igneous, sedimentary and metamorphic rocks around the world. …”
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“…We report the experimental application of distributed optical fiber sensors, based on stimulated Brillouin scattering (SBS), to the monitoring of a small-scale granular slope reconstituted in an instrumented flume and subjected to artificial rainfall until failure, and to the monitoring of a volcanic rock slope. The experiments demonstrate the sensors’ ability to reveal the sudden increase in soil strain that foreruns the failure in a debris flow phenomenon, as well as to monitor the fractures in the tuff rocks. …”
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“…This brief note presents geochemical data from rock samples from the Cabo Ortegal Complex (NW Spain). …”
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“…To realize continuous real-time monitoring of the large-scale internal strain field of coal and rock mass, a bidirectional strain sensor based on FBGs encapsulated using a hollow cylindrical steel tube was designed. …”
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