“…Rho-kinase (ROCK) activation in hepatic stellate cells (HSC) is a key mechanism promoting liver fibrosis and portal hypertension (PTH). …”
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“…A large number (1253) of high-quality streaming potential coefficient ([Formula: see text] measurements have been carried out on Berea, Boise, Fontainebleau, and Lochaline sandstones (the latter two including both detrital and authigenic overgrowth forms), as a function of pore fluid salinity ([Formula: see text] and rock microstructure. All samples were saturated with fully equilibrated aqueous solutions of NaCl (10[Formula: see text] and 4.5 mol/dm[Formula: see text] upon which accurate measurements of their electrical conductivity and pH were taken. …”
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“…[Image: see text] We have previously used surface chemistry analysis techniques to optimize the functionalization of carbonate rocks with a silylated polyacrylamide-based relative permeability modifier (RPM). …”
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“…Moreover, the expression and potential roles of ROCK and MLCK were also evaluated in the cultured macrophages. …”
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“…The expression of COL1-A1, α-SMA and RhoA/ROCK pathway genes was decreased in the activated HSCs treated with a miR-19b-3p mimic, indicating that miR-19b-3p inactivated HSCs by suppressing RhoA/ROCK signalling. …”
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“…HVICs were cultured in osteogenic medium as an in vitro model, and BMAL1 expression and location were detected. TGF-β and RhoA/ROCK inhibitors and RhoA-siRNA were applied to detect the mechanism underlying the source of BMAL1 during HVICs’ osteogenic differentiation. …”
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“…The risk of injury while attending punk rock concerts was 8.6 times higher than for pop concerts (p < .001). …”
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“…The microwave-assisted rock breaking technology has been proven to be feasible, and has received considerable attention in the field of civil and mining engineering. …”
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“…To resolve this concern, we devised a silica-based defluoridation sorbent from pumice rock obtained from the Paka volcano in Baringo County, Kenya. …”
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“…[Image: see text] Bedding has an important influence on the macroscopic and microscopic mechanical properties of coal, and the mechanical properties of coal and rock mass and acoustic emission characteristics are very important for rock burst monitoring and warning. …”
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“…Manatees (Antillean-, Amazonian, and African-) and dugongs belong to the Order Sirenia, and when combined with elephants and rock hyraxes, form the Paenungulata. A bilobed mononuclear cell has previously been identified in elephants and rock hyraxes, but not in manatees and dugongs, with cytochemical staining identifying these cells as bilobed monocytes in elephants. …”
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“…Paeonol decreased IBA‐1, IL1β, RhoA, RhoA‐GTP, COX2, Rock1, and p‐p38MAPK levels in the spinal dorsal horn. …”
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“…Assessing the rock physical and mechanical behavior under different temperatures has become of utmost importance. …”
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“…Moreover, the presence of weapons and rock art depicting scenes of combat supports the notion that these groups engaged in violence. …”
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“…The construction parameters of the step and CD methods are optimized to ensure the surrounding rock stability and tunnel safety. By relying on the Tongzi Tunnel, we simulate the excavation of different step heights in the construction of the top heading and benching method (HB) and CD methods through numerical simulation, the laws of tunnel vault settlement, and changes in the surrounding rock stress, initial support axial force, bending moment and safety factor. …”
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“…In response to the control problems of large-deformation roadways in close-distance coal seams, taking a typical roadway under irregular goafs and residual coal pillar in deep close-distance coal seams as the background, the characteristics of mine pressure and key difficulties in surrounding rock control of roadway are explored and an improvement strategy for controlling surrounding rock is proposed. …”
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“…The actin cytoskeleton drug cytochalasin B and the ROCK inhibitor Y-27632 inhibited FasL induction and caspase-3 activation, indicating that the newly identified Rho/Rock/actin signaling may regulate the downstream pro-apoptotic effectors in DU145 cells. …”
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“…RESULTS: Nineteen phosphate-solubilizing fluorescent Pseudomonas strains of P. fluorescens, P. poae, P. trivialis, and Pseudomonas spp. produced gluconic acid, oxalic acid, 2-ketogluconic acid, lactic acid, succinic acid, formic acid, citric acid and malic acid in the culture filtrates during the solubilization of tricalcium phosphate, Mussoorie rock phosphate, Udaipur rock phosphate and North Carolina rock phosphate. …”
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“…We show that MLCK, ROCK and myosin II are required for Slit and Netrin-1-mediated growth cone collapse of cranial motor axons. …”
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“…The highest median PCB level was found in rock sole (Lepidopsetta bilineata, 285 ppb, wet weight), while the lowest level was found in rock greenling (Hexagrammos lagocephalus, 104 ppb, wet weight). …”
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