“…CONCLUSION: This study is the first to demonstrate that IGF-1 treatment in NCMs and NCFs activates the ROCK, ASK-1 and p38MAPK pathways. Future research may be guided by consideration of the PI3K/Akt and ERK1/2 pathways potentially increasing collagen synthesis, and the utilisation of a biased agonist to reduce activation of the ROCK, ASK-1 and p38MAPK pathways to maximise cardioprotective benefit whilst mitigating risks.…”
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“…The results show that under high pressure, CO(2) effectively changes the pore structure through the extraction of hydrocarbons, dissolution of the rock matrix, and migration of minerals. CO(2) dissolution of the rock matrix can significantly increase the number and complexity of fractures. …”
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“…This experiment used a reservoir-on-a-chip that preserved the real rock properties and morphological features. Crude oil–water–rock contact angle experiments by altering water salinity were conducted to investigate the mechanism of the improvement of sweep efficiency by low-salinity water flooding. …”
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“…Non-additive stimulatory effect on neurite generation was also detected by the inhibition of Rho-associated, coiled-coil-containing protein kinase 1 (ROCK1), the upstream regulator of NMII. In contrast, inhibition of c-Jun N-terminal kinases (JNKs) had only a negligible effect, suggesting that the ROCK1 signal is dominantly manifested by actomyosin activity. …”
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“…Herein, we have successfully stabilized the high-pressure cubic rock-salt phase of SnSe by alloying with AgBiSe(2) (0.30 ≤ x ≤ 0.80) at ambient temperature and pressure. …”
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“…The deformation control technology of the roadway surrounding rock was proposed, verified by numerical simulation and applied to engineering practice. …”
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“…Estimating rock-mechanical, petrophysical properties and pre-production stress state is essential for effective reservoir planning, development, and optimal exploitation. …”
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“…Results: (1) Curling control consists of an acceleration phase and a stabilizing delivery phase; (2) the control of trunk, shoulder, and wrist are responsible for accelerating the rock; (3) elbow control is accountable for the accurate delivery of the rock; and (4) during the slow curling, a synchronized effort of trunk, shoulder, and wrist is used for accelerating the rock, while a sequential control among the segment/joints is applied in fast curling. …”
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“…We analyzed genetic markers of Grey and Rock Partridges from collections, wild populations and farms, mostly in Italy. …”
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“…During coal mining activities, dynamic disasters may be induced, such as coal and gas outbursts, or rock burst, resulting in serious accidents or disasters. …”
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“…Source fingerprinting done using petrographic, geochemical and isotopic data, suggests that contrary to the general perception, the anchor rock did not come from any local rock formations. …”
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“…For underground water-sealed oil storage, the spatial variability of the surrounding rock has a significant impact on the water-sealed effect of a water curtain system. …”
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“…Among these genes, we selected BRCC3, ROCK2 and ATG2B for validation. We showed that ROCK2 expression, basal autophagy and homologous recombination (HR) efficiency were increased in all OR cell lines. …”
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“…High ROCK1, TAGLN2, and FCHO2 expressions were indicative of low overall PC survival as found using the Kaplan–Meier plotter. …”
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“…In the oil and gas reservoirs, the interaction between the injected fluids and the reservoir fluids and rocks plays a major role in the productivity of any oil and gas field. …”
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“…Geological formations are often highly heterogeneous and entail complex nonlinear inelastic rock deformation physics when utilized for cyclic energy storage. …”
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“…The convergence-confinement method (CCM) is a simplified widely utilised tool for assessing the interplay between the rock mass behaviour and the support effect, so it is quite helpful for tunnel support design purposes. …”
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“…Crystals exist in nature (like rock crystal) but can also be synthesized. Some crystals can emit light when hit by a high-energy particle.…”
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