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  1. 4821
    “…The underlying mechanisms of biological effects of therapeutic ultrasound in PT medicine may be associated with the upregulation of cell proliferation through activation of integrin receptors and Rho/ROCK/Src/ERK signaling pathway, and with promoting multilineage differentiation of mesenchyme stem/progenitor cell lines through ROCK-Cot/Tpl2-MEK-ERK signaling pathway. …”
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    AB142. The characteristics and therapeutic applications of low-intensity pulsed ultrasound
  2. 4822
    “…In particular, we review the role of Rho-kinase (ROCK) in reactive gliosis and show that inhibiting ROCK after stroke results in reduced scar formation and improved functional recovery.…”
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    Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase
  3. 4823
    “…Recent studies showed that biological effects of LIPUS in healing morbid body tissues may be mainly associated with the upregulation of cell proliferation through activation of integrin receptors and Rho/ROCK/Src/ERK signaling pathway, and with promoting multilineage differentiation of mesenchyme stem/progenitor cell lines through ROCK-Cot/Tpl2-MEK-ERK signaling pathway. …”
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    Clinical applications of low-intensity pulsed ultrasound and its potential role in urology
  4. 4824
    “…These data support the hypothesis that keratin antibody reactivity can be used to identify the nature and composition of epidermal structures in the rock record, and to address evolutionary questions by distinguishing between alpha- (widely distributed) and beta- (limited to sauropsids) keratin.…”
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    Keratin Durability Has Implications for the Fossil Record: Results from a 10 Year Feather Degradation Experiment
  5. 4825
    “…Terrestrial core formation occurred in the early molten Earth by gravitational segregation of immiscible metal and silicate melts, stripping iron-loving elements from the silicate mantle to the metallic core1–3, and leaving rock-loving components behind. Here we performed experiments showing that at high enough temperature, Earth’s major rock-loving component, magnesium oxide, can also dissolve in core-forming metallic melts. …”
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    An early geodynamo driven by exsolution of mantle components from Earth’s core
  6. 4826
    “…Beach cleaning and rock pooling were associated with higher marine awareness. …”
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    Can Beach Cleans Do More Than Clean-Up Litter? Comparing Beach Cleans to Other Coastal Activities
  7. 4827
    “…Our data suggest that TAZ is an important mediator of LPA signaling in MSCs in the downstream of MEK and ROCK signaling.…”
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    Role of TAZ in Lysophosphatidic Acid-Induced Migration and Proliferation of Human Adipose-Derived Mesenchymal Stem Cells
  8. 4828
    “…Tensile strength and fracture toughness, important parameters of the rock for engineering applications are difficult to measure. …”
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    Calculation for tensile strength and fracture toughness of granite with three kinds of grain sizes using three-point-bending test
  9. 4829
    “…In this study, based on direct tension tests, full tensile load–displacement curves of rock bolts with different groove shapes were obtained and analyzed. …”
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    Study on the Optimal Groove Shape and Glue Material for Fiber Bragg Grating Measuring Bolts
  10. 4830
    “…MLCK and the Rho kinase ROCK are expressed in distinct subsets of spermathecal cells and act in concert to coordinate the timing of contraction. …”
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    The myosin light-chain kinase MLCK-1 relocalizes during Caenorhabditis elegans ovulation to promote actomyosin bundle assembly and drive contraction
  11. 4831
    “…The structural geology data include: dyke locations, orientations, thickness and marginal lineations, in addition to country rock bedding and kinematic data from nearby faults. …”
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    Structural geology data and 3-D subsurface models of the Budgell Harbour Stock and associated dykes, Newfoundland, Canada
  12. 4832
    “…Measuring multiple cosmogenic nuclides in the same rock sample has a great potential, but data interpretation requires rigorous and often complex mathematical treatments. …”
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    Two MATLAB programs for computing paleo-elevations and burial ages from paired-cosmogenic nuclides
  13. 4833
    “…This work reveals a set of surface topography parameters that are significant for algal attachment to natural rock substrata. Topography analysis of rock surfaces from a stream identifies three descriptive areal parameters (S(mr), S(v), and S(a)) that correlate with the presence of natural periphyton community. …”
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    Engineering of bio-mimetic substratum topographies for enhanced early colonization of filamentous algae
  14. 4834
    por Defant, Andrea, Mancini, Ines
    Publicado 2019
    “…By screening the full National Cancer Institute (NCI) panel, including 60 human cancer cell lines, four molecules displayed good and sometimes better growth inhibition GI(50) than the ROCK inhibitor Y-27632, the Topo II inhibitor podophyllotoxin and the tubulin inhibitor combretastatin A-4. …”
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    Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules
  15. 4835
    “…Early initiation of a ROCK inhibitor was a successful treatment for this patient.…”
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    A Case Report Illustrating the Postoperative Course of Descemetorhexis without Endothelial Keratoplasty with Topical Netarsudil Therapy
  16. 4836
    “…Rho-associated kinases (ROCKs) play a crucial role in hPSC survival. To date, a typical ROCK inhibitor, Y-27632, has been the primary agent used in hPSC research. …”
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    The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research
  17. 4837
    “…This is the first reported case of a successful resolution of cystic-like foveal cavities in eyes with X-linked juvenile retinoschisis (XLRS) treated with topical ripasudil hydrochloride hydrate, a Rho-associated coiled/coil-containing protein kinase (ROCK) inhibitor. A chart review was performed on 1 patient to collect all relevant clinical information and the optical coherence tomographic (OCT) images. …”
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    Effectiveness of Ripasudil, a Rho-Associated Coiled/Coil-Containing Protein Kinase Inhibitor, in Improving Retinoschisis and Cystic-Like Foveal Cavities in Eyes with X-Linked Retinoschisis
  18. 4838
    “…Micromagnetic tomography therefore enables a new approach for detailed rock magnetic studies on large ensembles of individual particles.…”
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    Single Particle Multipole Expansions From Micromagnetic Tomography
  19. 4839
    “…Six zeolite-bearing rocks, often used as building materials, were analyzed by thermodilatometry, together with a rock not bearing zeolites and a plaster covering a containing wall made of zeolite-bearing dimension stones, up to 250 °C. …”
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    Thermodilatometric Study of the Decay of Zeolite-Bearing Building Materials
  20. 4840
    “…On this basis, the energy absorption and release in rocks surrounding a roadway during the evolution thereof in a coal reservoir tend to rock bursting were quantified. …”
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    Energy release induced rockbursts based on butterfly-shaped plastic zones in roadways of coal reservoirs
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