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  1. 4881
    “…The aim of this study was to evaluate the potential of Aspergillus tubingensis in extracting metals from rocks simulating Martian regolith through biomining. …”
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    Interaction between a Martian Regolith Simulant and Fungal Organic Acids in the Biomining Perspective
  2. 4882
    “…The influences of wettability and rock particle shape on flow characteristics were studied based on the characteristics of saturation and pressure distribution. …”
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    The Micro-Flow Mechanism of Polymer Flooding in Dual Heterogeneous Reservoirs Considering the Wettability
  3. 4883
    “…This study aims to address this gap using SmartRock sensor technology to further understand the compaction mechanisms of different asphalt surface courses from a particle perspective, as well as the relationship between aggregate acceleration and compaction degree. …”
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    Optimizing Asphalt Surface Course Compaction: Insights from Aggregate Triaxial Acceleration Responses
  4. 4884
    “…Of particular interest, a negative association between patterns of variational modularity was observed between the sand and rock-dwelling clades, a patter consistent with character displacement. …”
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    Modularity of the Oral Jaws Is Linked to Repeated Changes in the Craniofacial Shape of African Cichlids
  5. 4885
    “…We established that IGFBP-3 activated Rho, the upstream regulator of ROCK and that beta1 integrin and PKA were upstream of Rho activation, whereas the involvement of ceramide was downstream. …”
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    Intrinsic, Pro-Apoptotic Effects of IGFBP-3 on Breast Cancer Cells are Reversible: Involvement of PKA, Rho, and Ceramide
  6. 4886
    “…Since rock climbing grows in popularity, the number of the respective scientific reports increases. …”
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    Somatic Profile of Competitive Sport Climbers
  7. 4887
    “…Methanol extract of BF (bark) inhibited Rho-kinase 2 (ROCK-II) enzyme activity in vitro with an IC(50) of 20.29 ± 1.83 μg/mL. …”
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    Erectogenic and Aphrodisiac Effects of Butea frondosa Koenig ex Roxb. in Rats: Involvement of Enzyme Inhibition
  8. 4888
    por Elahi, Robin, Sebens, Kenneth P.
    Publicado 2013
    “…In this study, we tested the hypothesis that red urchins and lined chitons (Tonicella spp.) are redundant in the maintenance of available space, defined as encrusting algae and bare rock. In a factorial field experiment replicated at three sites, we reduced the densities of urchins and chitons on subtidal rock walls for nine months. …”
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    Experimental Removal and Recovery of Subtidal Grazers Highlights the Importance of Functional Redundancy and Temporal Context
  9. 4889
    “…Rounded-amoeboid cancer cells use actomyosin contractility driven by Rho-ROCK and JAK-STAT3 to migrate efficiently. It has been suggested that rounded-amoeboid cancer cells do not require matrix metalloproteinases (MMPs) to invade. …”
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    Diverse matrix metalloproteinase functions regulate cancer amoeboid migration
  10. 4890
    “…BACKGROUND: Two isoforms of Rho-associated protein kinase (ROCK), ROCKI and ROCKII, play a pivotal role in regulation of cytoskeleton and are involved in multiple cellular processes in mammalian cells. …”
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    Ser1333 phosphorylation indicates ROCKI activation
  11. 4891
    por Zhao, Lili, Yang, Gongshe, Zhao, Xin
    Publicado 2014
    “…The role of Rho-associated protein kinases (ROCKs) in the differentiation process was then studied by using ROCK-specific inhibitor Y-27632 and ROCK siRNAs. …”
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    Rho-Associated Protein Kinases Play an Important Role in the Differentiation of Rat Adipose-Derived Stromal Cells into Cardiomyocytes In Vitro
  12. 4892
    “…Our results reveal a crucial role of ROCK-controlled directional cell movements during rabbit primitive streak formation and highlight the possibility that temporal and spatial modulation of cell movements were instrumental for the evolution of gastrulation forms.…”
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    Rho kinase activity controls directional cell movements during primitive streak formation in the rabbit embryo
  13. 4893
    “…Increased sexual reproductive effort was associated with rock outcrop type and may be a response to adverse conditions for growth and vegetative reproduction. …”
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    Genetic Structure Is Associated with Phenotypic Divergence in Floral Traits and Reproductive Investment in a High-Altitude Orchid from the Iron Quadrangle, Southeastern Brazil
  14. 4894
    “…In addition, cofilin-1 and α-actinin translocate to actin coats. ROCK1-dependent regulated actin depolymerisation by cofilin-1 in cooperation with actin crosslinking by α-actinin is essential for complete coat contraction. …”
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    Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles
  15. 4895
    “…Inhibition of RLC phosphorylation using inhibitors against ROCK, but not PKC and MRCK, or overexpression of phospho-dead mutant of RLC enhances membrane fusion. …”
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    Phosphorylation of Nonmuscle myosin II-A regulatory light chain resists Sendai virus fusion with host cells
  16. 4896
    “…The migration of BMSCs in the 5A group was abolished by blocking the RhoA/ROCK signaling pathway with Y27632. The in vivo study demonstrated that implantation of 5A significantly improved osseointegration. …”
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    Effects of Artificial Ligaments with Different Porous Structures on the Migration of BMSCs
  17. 4897
    “…Vertical splitting cracks often appear in side walls of large-scale underground caverns during excavations owing to the brittle characteristics of surrounding rock mass, especially under the conditions of high in situ stress and great overburden depth. …”
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    Splitting failure in side walls of a large-scale underground cavern group: a numerical modelling and a field study
  18. 4898
    “…Thirty samples were collected from five mineral ores (rock phosphate, rutile, zircon, coal and hematite) and analyzed for (238)U, (234)U, (226)Ra, (210)Pb, (235)U, (232)Th, (228)Ra, (228)Th and (40)K using delayed neutron activation analysis and low energy gamma spectroscopy. …”
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    Health Effects Due to Radionuclides Content of Solid Minerals within Port of Richards Bay, South Africa
  19. 4899
    “…Since Ophn1-deficient mice display overactivation of Rho-associated protein kinase (ROCK) and protein kinase A (PKA) signaling, we administered a clinically approved ROCK/PKA inhibitor (fasudil) to correct the neurogenesis defects. …”
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    Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability
  20. 4900
    “…Hmga2 translocation to the nucleus could in part be prevented by an inhibitor for ROCK1. Our findings demonstrate that upon program of benign papilloma to malignant cSCC of skin tumorigenesis, Hmga2 translocates in a ROCK-dependent manner from the membrane to the nucleus, where it serves as an autoregulatory transcription factor, causing cell transformation.…”
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    Hmga2 translocation induced in skin tumorigenesis
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