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5181por Riou, Philippe, Kjær, Svend, Garg, Ritu, Purkiss, Andrew, George, Roger, Cain, Robert J., Bineva, Ganka, Reymond, Nicolas, McColl, Brad, Thompson, Andrew J., O’Reilly, Nicola, McDonald, Neil Q., Parker, Peter J., Ridley, Anne J.“…Here, we report a high-affinity 14-3-3-binding site at the C terminus of Rnd3 consisting of both the Cys241-farnesyl moiety and a Rho-associated coiled coil containing protein kinase (ROCK)-dependent Ser240 phosphorylation site. 14-3-3 binding to Rnd3 also involves phosphorylation of Ser218 by ROCK and/or Ser210 by protein kinase C (PKC). …”
Publicado 2013
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5182“…Our data indicate that ROCK and the related trafficking pathway genes regulate neuronal necrosis. …”
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5183“…These "players" played rock-paper-scissors against the pre-recorded opponents in a variety of conditions. …”
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5184“…A 0.6 hectare artificial reef of local rock and recycled concrete sleepers was constructed in December 2006 at Parker Point in the industrial port of Dampier, western Australia, with the aim of providing an environmental offset for a nearshore coral community lost to land reclamation. …”
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5185“…Selective knock-down of components of the Rho pathway (RhoA, RhoC, Rho-associated protein kinase 1 (ROCK1) and ROCK2) showed that Rho signalling is crucial to TEM. …”
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5186“…The OmB and OmL cell lines were generated without or with Rho-associated kinase (ROCK) inhibitor/3T3 feeder layer supplementation. …”
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5187por Vogel, Ineke, van de Looij-Jansen, Petra M., Mieloo, Cathelijne L., Burdorf, Alex, de Waart, Frouwkje“…Temporary hearing symptoms that occurred after using an MP3 player or going to a discotheque or pop/rock concert were associated with exposure to high-volume music. …”
Publicado 2014
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5188“…The Rho/ROCK pathway is a promising therapeutic target in neurodegenerative and neurotraumatic diseases. …”
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5189“…BACKGROUND: Rho-kinases (ROCKs), a family of small GTP-dependent enzymes, are involved in a range of pain models, and their inhibition typically leads to antinociceptive effects. …”
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5190por Ouyang, Qiu-Fang, Han, Ying, Lin, Zhi-Hong, Xie, Hong, Xu, Chang-Sheng, Xie, Liang-Di“…Fluvastatin upregulated LTCCα (1C) expression, at least in part, by inhibiting ROCK, ERK1/2, and p38 MAPK activation. Fluvastatin may be a potential candidate for preventing or treating vascular diseases.…”
Publicado 2014
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5191por Phillips, C. B., Iline, I. I., Novoselov, M., McNeill, M. R., Richards, N. K., van Koten, C., Stephenson, B. P.“…Our experimental conditions simulated shipping of rock melons from Australia to New Zealand by sea and air. …”
Publicado 2014
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5192por Wu, Yucheng, Tan, Liangcheng, Liu, Wuxing, Wang, Baozhan, Wang, Jianjun, Cai, Yanjun, Lin, Xiangui“…The deposits on the cave walls were dominated by putative cave-specific bacterial lineages within the γ-Proteobacteria or Actinobacteria that are routinely found on cave rocks around the world. In addition, sequence identity with known functional groups suggests enrichments of chemolithotrophic bacteria potentially involved in autotrophic C fixation and inorganic N transformation on rock surfaces. …”
Publicado 2015
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5193“…Constitutive ATP release was decreased, while hypoxia-induced release was abolished by brefeldin or monensin A, inhibitors of vesicular transport, and LY294002 or Y27632, inhibitors of phosphoinositide 3-kinases (PI(3)K) and Rho-associated protein kinase (ROCK). ATP release was unaffected by NO donor, but increased by calcium ionophore, by >60-fold from apical, but <25% from basolateral surface. …”
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5194“…These individual minerals and whole-rock field samples were reacted in the laboratory with 1 molal sulfuric acid at varying temperatures (65, 150, and 200°C), fluid:rock weight ratios (1:1, 4:1, and 10:1), and durations (1–60 days). …”
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5195“…The expression levels of ROCK2, cyclin D1 and Bcl-2 were reduced by the downregulation of AMFR and enhanced by overexpression of AMFR-C. …”
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5196por Bao, Zhiyao, Han, Xuelin, Chen, Fangyan, Jia, Xiaodong, Zhao, Jingya, Zhang, Changjian, Yong, Chen, Tian, Shuguang, Zhou, Xin, Han, Li“…CONCLUSION: These results indicated that cofilin might be involved in the modulation of A. fumigatus internalization into type II alveolar epithelial cells through the RhoA-ROCK-LIM kinase pathway.…”
Publicado 2015
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5197por Terres, Maria A., Lawrence, Emma, Hosack, Geoffrey R., Haywood, Michael D. E., Babcock, Russell C.“…Strong positive relationships between the presence of snapper and rock habitat, particularly rocky substrate composed of indurated freshwater sediments known as coffee rock, and kelp habitat reinforce the consideration of habitat availability in marine reserve design and the design of any associated monitoring programs.…”
Publicado 2015
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5198por Mahmood, Irfan, Qureshi, Shahid Nadeem, Tariq, Shahina, Atique, Luqman, Iqbal, Muhammad Farooq“…These landslides were mainly rock and debris falls. Hattian Bala rock avalanche was largest landslide associated with the earthquake which completely destroyed a village and blocked the valley creating a lake. …”
Publicado 2015
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5199por Nyakatura, John A., Allen, Vivian R., Lauströer, Jonas, Andikfar, Amir, Danczak, Marek, Ullrich, Hans-Jürgen, Hufenbach, Werner, Martens, Thomas, Fischer, Martin S.“…Quantitative analysis of anatomical information suffers from fragmentation of fossil bones, plastic deformation due to diagenetic processes and fragile preservation within surrounding rock matrix, preventing further biomechanical investigation. …”
Publicado 2015
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5200por Griggio, Matteo“…For 3 years, I investigated the brood desertion modality of the rock sparrow. Then, for 2 years, I removed a group of experimental nest boxes during the autumn. …”
Publicado 2015
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