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  1. 5281
    “…Subsequently, osteoblasts were pretreated with ROCK specific inhibitor Y27632 to observe the changes of actin skeleton after X-ray irradiation. …”
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    Low-dose X-ray irradiation induces morphological changes and cytoskeleton reorganization in osteoblasts
  2. 5282
    “…Rho-associated protein kinase 2 (ROCK2) is a membrane-anchored, long, flexible, multidomain, multifunctional protein. …”
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    Ligand-induced conformational rearrangements regulate the switch between membrane-proximal and distal functions of Rho kinase 2
  3. 5283
    “…Here we report ancient maize genomes (2,300–1,900 cal. BP) from El Gigante rock shelter, Honduras, that are closely related to ancient and modern maize from South America. …”
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    Archaeological Central American maize genomes suggest ancient gene flow from South America
  4. 5284
    “…We found significant involvement of RhoA/ROCK (Rho-Associated Protein Kinase) signaling in mediating ectopic calcification of muscles in dKO mice. …”
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    Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice
  5. 5285
    “…We carried out a series of experiments to constrain conditions that led to the vitrification of the inner wall rocks in the hillfort at Broborg, Sweden. Potential source rocks were collected locally and heat treated in the laboratory, varying maximum temperature, cooling rate, and starting particle size. …”
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    Reproduction of melting behavior for vitrified hillforts based on amphibolite, granite, and basalt lithologies
  6. 5286
    “…In addition, the expression levels of p‐RhoA/RhoA, ROCK1/2 and p‐MLC/MLC were measured in human NP cells under compression stress and in degenerative IVD tissues. …”
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    The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells
  7. 5287
    “…This review provides a comprehensive update on emerging ROCK inhibitors as an innovative treatment option for lowering intraocular pressure (IOP) in glaucoma and aims to describe the structure, mechanism of action, pharmaceutical characteristics, desirable ocular effects, including side effects for each agent. …”
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    Investigational Rho Kinase Inhibitors for the Treatment of Glaucoma
  8. 5288
    “…Concluding, here we provide preliminary evidence of the involvement of the Hippo pathway in human tumor parathyroid cells and of the existence of a CASR-ROCK-YAP1 axis. We propose a tumor suppressor role for YAP1 and LATS1/2 in parathyroid tumors.…”
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    Yes-Associated Protein 1 Is a Novel Calcium Sensing Receptor Target in Human Parathyroid Tumors
  9. 5289
    “…Targeting DR5‐ROCK1‐PD‐L1 axis markedly increases immune effector T‐cell function, promotes tumor regression, and improves overall survival in animal models. …”
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    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
  10. 5290
    “…Our rabbit intestinal spheroid and monolayer cultures grew most efficiently in L-WRN-conditioned medium that contained Wnt, R-spondin and Noggin, and that had been supplemented with ROCK and TGF-β inhibitors. Organoid and monolayer differentiation was initiated by reducing the concentration of the L-WRN-conditioned medium and by adding ROCK and Notch signalling inhibitors. …”
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    Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers
  11. 5291
    “…Blocking ROCK prevented p38 activation, suggesting that MAGI1 limits p38 activity in part through releasing actin strength. …”
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    MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis
  12. 5292
    “…However, our understanding of the relative contributions of rock-derived, or geogenic, N to the total N supply of mountainous watersheds remains poorly understood. …”
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    Modeling geogenic and atmospheric nitrogen through the East River Watershed, Colorado Rocky Mountains
  13. 5293
    “…To improve the resistance of tomato against Fusarium oxysporum f. sp. lycopersici (FOL), Escherichia coli katE gene was transformed into two tomato cultivars, namely Castle Rock and Super strain B, via Agrobacterium tumefaciens; the transformation efficiency was 5.6% and 3.5%, respectively. …”
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    Overexpression of bacterial katE gene improves the resistance of modified tomato plant against Fusarium oxysporum f. sp. lycopersici
  14. 5294
    “…The thermochemical structure of lithospheric and asthenospheric mantle exert primary controls on surface topography and volcanic activity. Volcanic rock compositions and mantle seismic velocities provide indirect observations of this structure. …”
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    Global influence of mantle temperature and plate thickness on intraplate volcanism
  15. 5295
    “…A new non-dispersive, anti-washout grout consisting of ordinary Portland cement, slag, superplasticizer, and methylbenzyl cellulose is proposed herein for the treatment of open karst, jointed and fractured rock, open-work gravel, and permeable sediments. …”
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    Non-Dispersive Anti-Washout Grout Design Based on Geotechnical Experimentation for Application in Subsidence-Prone Underwater Karstic Formations
  16. 5296
    “…We show a wide range of numerical applications that are relevant for dynamic earthquake rupture in fault zones, including the co-seismic generation of secondary off-fault shear cracks, tensile rock fracture in the Brazilian disc test, as well as a natural convection problem in molten rock-like material. …”
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    A unified first-order hyperbolic model for nonlinear dynamic rupture processes in diffuse fracture zones
  17. 5297
    “…The results indicate that the q values of the 12 influencing factors vary obviously, and the dominant factors are also different for the 3 types of landslides, with annual mean precipitation (AMP) being the dominant factor for rockslide distribution, elevation being the dominant factor for rock fall distribution and lithology being the dominant factor for flow-like distribution. …”
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    Analysis of the spatial association of geographical detector-based landslides and environmental factors in the southeastern Tibetan Plateau, China
  18. 5298
    “…However, one constraint of surfactant flooding is the loss of the surfactant by adsorption onto the reservoir rock surface. Hence, in this study, an attempt has been made to reduce the adsorption of the surfactant on the rock surface using novel colloidal silica nanoparticles (CSNs). …”
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    Application of Novel Colloidal Silica Nanoparticles in the Reduction of Adsorption of Surfactant and Improvement of Oil Recovery Using Surfactant Polymer Flooding
  19. 5299
    “…We compared the genomes of rock- and sand-dwelling species and asked which genetic variants differed among the groups. …”
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    Genome-enabled discovery of evolutionary divergence in brains and behavior
  20. 5300
    por Hu, Bin, Cui, Aneng, Cui, Kai, Liu, Yang, Li, Jing
    Publicado 2021
    “…Mudstone interlayer is a weak layer in rock engineering. When it is subjected to continuous stress higher than its damage threshold, due to the dislocation of particles in mudstone crystals and the expansion of cracks, mudstone strength is gradually damaged and deteriorated and the strain gradually increases, thus accelerating the phenomenon of creep damage. …”
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    A novel nonlinear creep model based on damage characteristics of mudstone strength parameters
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